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Thromb Haemost 1977; 38(04): 1054-1072
DOI: 10.1055/s-0038-1651923
DOI: 10.1055/s-0038-1651923
Original Article
Factor VIII-Associated Platelet Aggregation
Further Information
Publication History
Publication Date:
04 July 2018 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00035024/197702/lookinside/thumbnails/10-1055-s-0038-1651923-1.jpg)
* Recipient of a Research Career Development Award #HL 00275. This work was supported by the National Institutes of Health, grants #HL 15474 and HL14217.
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References
- 1 Allain J. P, Cooper H. A, Wagner R. H, Brinkhous K. M. 1975; Platelets fixed with paraformaldehyde: A new reagent for assay of von Willebrand factor and platelet aggregating factor. Journal of Laboratory and Clinical Medicine 85: 318.
- 2 Andersen J. C, McKee P. A. 1974; The effect of plasmin on the structure and function of human factor VIII. Circulation 50 (Suppl. 03) 281 (abstract).
- 3 Anderson J, Gralnick H, Corash L. 1976; Partial characterization of platelet-associated Factor VIII. Circulation 53 (Suppl. 02) 115 (abstract).
- 4 Atichartakarn V, Kirby E. P, Marder V. J, Budzynski A. Z. 1976; Proteolytic and thermal degradation studies of human factor VIII preparations. Blood 48: 1004 (abstract).
- 5 Austen D. E. G, Carey M, Howard M. A. 1975; Dissociation of Factor VIII-related antigen into subunits. Nature 253: 55.
- 6 Barrow E. S, Reisner H. M, Graham J. B. 1977; The separation of Willebrand factor from factor VIII-related antigen. Thrombosis and Haemostasis 38: 38 (abstract).
- 7 Baugh R. F, Brown J. E, Hougie C. 1975; Plasma components which interfere with ristocetin – induced platelet aggregation. Thrombosis et Diathesis Haemorrhagica 33: 540.
- 8 Baugh R. F, Brown J. E, Hougie C. 1977; Preparation and platelet aggregation activity of 125I-labelled ristocetin. Analytical Biochemistry 78: 39.
- 9 Baugh R. F, Burnand C, Hougie C. 1977; Isolation of an apparently abnormal von Willebrand factor: Comparison with plasma and serum von Willebrand factor. Thrombosis and Haemostasis 38: 2 (abstract).
- 10 Baugh R. F, Burnand C, Hougie C, Wolf P. 1977; The effect of vancomycin on ristocetin and bovine PAF aggregation of human platelets. Federation Proceedings 36: 1083 (abstract).
- 11 Bottecchia D, Vermylen J. 1976; Factor VIII and human platelet aggregation. II. Characteristics of aggregation of human platelets by bovine Factor VIII. British Journal of Haematology 34: 313.
- 12 Bouma B. N, Degraaf S, Zimmerman T. S. 1977; Human blood platelet factor VIII-related antigen: a glycocalidn-like protein. Thrombosis and Haemostasis 38: 126 (abstract).
- 13 Bouma B. N, Hordjik-Hos J. M, Degraaf S, Sixma J. J. 1975; Presence of Factor VIII-related antigen in blood platelets of patients with von Willebrand’s disease. Nature 257: 510.
- 14 Brass L. F, Faile D, Bensusan H. B. 1976; Direct measurement of the platelet: collagen interaction by affinity chromatography on collagen/Sepharose. Journal of Laboratory and Clinical Medicine 87: 525.
- 15 Brown J. E, Baugh R, Hougie C. 1976; Selective destruction of the platelet aggregation component in bovine Factor VIII preparations by reduction. Thrombosis Research 8: 777.
- 16 Brown R. S, Niewiarowski S, Stewart G. J, Millman M. 1977; A double-isotope study on incorporation of platelets and red cells into fibrin. Journal of Laboratory and Clinical Medicine 90: 130.
- 17 Caen J. P, Michel H, Tobelem G, Bodevin E, Levy-Toledano S. 1977; Adhesion and aggregation of human platelets to rabbit subendothelium. A new approach for investigation: Specific antibodies. Experientia 33: 91.
- 18 Caen J. P, Castaldi P. A, Leclerc J. C, Inceman S, Larrieu M. J, Probst M, Bernard J. 1966; Congenital bleeding disorders with long bleeding time and normal platelet count. I. Glanzmann’s thrombasthenia (Report of fifteen patients). American Journal of Medicine 41: 4.
- 19 Caen J. P, Nurden A. T, Jeanneau C, Michel H, Tobelem G, Levy-Toledano S, Sultan Y, Valensi F, Bernard J. 1976; Bernard-Soulier syndrome: A new platelet glycoprotein abnormality. Its relationship with platelet adhesion to subendothelium and with the Factor VIII von Willebrand protein. Journal of Laboratory and Clinical Medicine 87: 586.
- 20 Chao F. C, Tullís J. L, Connelly G. S, Lawler J. W. 1976; Aggregation of platelets and inert particles induced by thrombin. Thrombosis and Haemostasis 35: 717.
- 21 Chediak J. R, Telfer M. C, Green D. 1977; Platelet function and immunologic parameters in von Willebrand’s disease following cryoprecipitate and Factor VIII concentrate infusion. American Journal of Medicine 62: 369.
- 22 Cohen I, Glaser T, Seligsohn U. 1975; Effects of ADP and ATP on bovine fibrinogen- and ristocetin-induced platelet aggregation in Glanzmann’s thrombasthenia. British Journal of Haematology 31: 343.
- 23 Coller B. S, Franza Jr B. R, Gralnick H. R. 1976; The pH dependence of quantitative ristocetin-induced platelet aggregation: Theoretical and practical implications – A new device for maintenance of platelet-rich plasma pH. Blood 47: 841.
- 24 Coller B. S, Gralnick H. R. 1976; Biochemical mechanism of ristocetin (R) induced agglutination (A) of platelets (P). Clinical Research 24: 305 A (abstract).
- 25 Coller B. S, Hirschman R. J, Gralnick H. R. 1975; Studies on the factor VIII/von Willebrand factor antigen on human platelets. Thrombosis Research 6: 469.
- 26 Cooper H. A, Barnes D. S, Wagner R. H. 1975; Dithiothreitol reduction of bovine platelet aggregating factor (PAF). Blood 46: 1048 (abstract).
- 27 Cooper H. A, Lee D, Lamb M. A, Wagner R. H. 1977; The apparent separation of factor VIII-related antigen and coagulant activity from von Willebrand factor. Thrombosis and Haemostasis 38: 71 (abstract).
- 28 Fass D. N, Bowie E. J. W. 1977; Reduced polymerization of Willebrand factor in a family of pigs with a variant of von Willebrand’s disease. Thrombosis and Haemostasis 38: 86 (abstract).
- 29 Firkin B. G, Goh A, Stott L, Farmer S, Brodie G, Koutts J. 1975. The platelet in von Willebrand’s disease. In: Platelets. (ed.) Ulutin O. N. Excerpta Medica; Amsterdam: 406.
- 30 Floyd M, Burns W, Green D. 1977; On the interaction between ristocetin and the ristocetin cofactor (RCOF). Thrombosis Research 10: 841.
- 31 Forbes C. D, Prentice C. R. M. 1973; Aggregation of human platelets by purified porcine and bovine antihemophilic factor. Nature, New Biology 241: 149.
- 32 George J. N, Potterf R. D, Lewis P. C, Sears D. A. 1976; Studies on platelet plasma membranes. I. Characterization of surface proteins of human platelets labelled with diazotized [125I]-diiodosulfanilic acid. Journal of Laboratory and Clinical Medicine 88: 232.
- 33 Goh A. T. W, Firkin B. C. 1976; Further studies of the interaction between ristocetin and fibrinogen. Haemostasis 5: 57.
- 34 Gralnick H. R, Coller B. S. 1976; Molecular defects in Haemophilia A and von Willebrand’s disease. Lancet I: 837.
- 35 Grant R. A, Zucker M. B, McPherson J. 1976; ADP-induced inhibition of von Willebrand factor-mediated platelet agglutination. American Journal of Physiology 230: 1406.
- 36 Green D, Muller H. 1976; Platelet binding of ristocetin cofactor. Circulation 53 (Suppl. 02) 116 (abstract).
- 37 Green D, Potter E. V. 1976; Platelet-bound ristocetin aggregation factor in normal subjects and patients with von Willebrand’s disease. Journal of Laboratory and Clinical Medicine 87: 976.
- 38 Greenberg J, Packham M. A, Cazenave J. P, Reimers H. J, Mustard J. F. 1975; Effects on platelet function of removal of platelet sialic acid by neuraminidase. Laboratory Investigation 32: 476.
- 39 Greenberg J. H, Jamieson G. A. 1974; The effects of various lectins on platelet aggregation and release. Biochemica et biophysica acta 345: 231.
- 40 Griggs T. R, Cooper H. A, Webster W. P, Wagner R. H, Brinkhous K. M. 1973; Plasma aggregating factor (bovine) for human platelets: A marker for study of antihemophilic and von Willebrand factors. Proceedings of the National Academy of Sciences (U.S.) 70: 2814.
- 41 Grottum K. A. 1969; Platelet surface charge and aggregation. Effects of polyelectrolytes. Thrombosis et Diathesis Haemorrhagica 21: 450.
- 42 Grottum K. A, Solum N. O. 1969; Congenital thrombocytopenia with giant platelets: A defect in the platelet membrane. British Journal of Haematology 16: 277.
- 43 Guisasola J. A, Cockburn C, Hardisty R. M. 1977; Von Willebrand factor activity in plasmin digests of factor VIII. Thrombosis and Haemostasis 38: 72 (abstract).
- 44 Handin R. I, Martin V, Maloney W. C. 1976; Antibody-induced von Willebrand’s disease: A newly defined inhibitor syndrome. Blood 48: 393.
- 45 Hasitz M, Okamura T, Jamieson G. A. 1977; Purification of membrane-bound glycoprotein I. Thrombosis and Haemostasis 38: 305 (abstract).
- 46 Hovig T. 1965; The effect of various enzymes on the ultrastructure, aggregation, and clot retraction ability of rabbit blood platelets. Thrombosis et Diathesis Haemorrhagica 13: 84.
- 47 Howard M. A. 1975; Inhibition and reversal of ristocetin-induced platelet aggregation. Thrombosis Research 6: 489.
- 48 Howard M. A, Firkin B. G. 1971; Ristocetin – a new tool in the investigation of platelet aggregation. Thrombosis et Diathesis Haemorrhagica 26: 362.
- 49 Howard M. A, Hutton R. A, Hardisty R. M. 1973; Hereditary giant platelet syndrome: A disorder of a new aspect of platelet function. British Medical Journal 4: 586.
- 50 Howard M. A, Montgomery D. C, Hardisty R. M. 1974; Factor-VIII-related antigen in platelets. Thrombosis Research 4: 617.
- 51 Howard M. A, Sawers R. J, Firkin B. G. 1973; Ristocetin: A means of differentiating von Willebrand’s disease into two groups. Blood 41: 687.
- 52 Jaffe E. A, Nachman R. L. 1975; Factor VIII binding protein in human platelets. Clinical Research 23: 276 (abstract).
- 53 Jeanneau C, Sultan Y, Savariau E, Caen J. 1977; Localization of Factor VIII antigen in platelets and megakaryocytes of normal and von Willebrand patients. (Electron microscopy studies with peroxidase labelled antibodies). Thrombosis and Haemostasis 38: 2 (abstract).
- 54 Jenkins C. S. P, Meyer D, Dreyfus M. D, Larrieu M. J. 1974; Willebrand Factor and ristocetin. I. Mechanism of ristocetin-induced platelet aggregation. British Journal of Haematology 28: 561.
- 55 Jenkins C. S. P, Meyer D, Larrieu M. J. 1976; Interaction of ristocetin and von Willebrand Factor. Thrombosis and Haemostasis 35: 752.
- 56 Jenkins C. S. P, Packham M. A, Kinlough-Rathbone R. L, Mustard J. F. 1971; Interactions of polylysine with platelets. Blood 37: 395.
- 57 Kattlove H. E, Gomez M. H. 1975; Studies on the mechanism of ristocetin-induced platelet aggregation. Blood 45: 91.
- 58 Kernoff P. B. A, Gruson R, Rizza C. R. 1974; A variant of Factor VIII related antigen. British Journal of Haematology 26: 435.
- 59 Kirby E. P. 1975; Evans blue: A specific inhibitor of Factor VIII-induced platelet agglutination. Thrombosis et Diathesis Haemorrhagica 34: 770.
- 60 Kirby E. P. 1976; Purification of the procoagulant portion of bo vine factor VIII. Circulation 53 (Suppl. 02) 119 (abstract).
- 61 Kirby E. P, Mills D. C. B. 1975; The interaction of bovine Factor VIII with human platelets. Journal of Clinical Investigation 56: 491.
- 62 Kirby E. P, Tang S. M. 1977; The binding of bovine Factor VIII to human platelets. Thrombosis and Haemostasis 38: 126 (abstract).
- 63 Koutts J, Lavergne J. M, Meyer D. 1977; Immunological evidence that human factor VIII is composed of two linked moitiés. Thrombosis and Haemostasis 38: 40 (abstract).
- 64 Koutts J, Meyer D, Rickard K, Stott L, Firkin B. G. 1975; Heterogeneity in biological activity of human factor VIII antibodies. British Journal of Haematology 29: 99.
- 65 Larcan A, Streiff F, Stoltz J. F, Alexandro P, Nicolas A. 1973; Action de deux polybases sur la charge et l’aggregation des plaquettes. Experientia 28: 1096.
- 66 Legaz M. E, Schmer G, Counts R. B, Davie E. W. 1973; Isolation and characterization of human Factor VIII (Antihemophilic Factor). Journal of Biological Chemistry 248: 3946.
- 67 Levy-Toledano S, Caen J. P, Halmos T, Mester L. 1973; Dissociation between human platelet agglomerating activity and Factor VIII procoagulant activity of bovine plasma preparations by chemical treatment. I. Effect of neuraminidase. Pathologie et Biologie 21 Suppl. 60.
- 68 Macfarlane D. E. 1976; Inhibition of bovine factor VIII and ristocetin plus human factor VIII induced platelet agglutination by small peptides. Thrombosis et Diathesis Haemorrhagica 34: 582 (abstract).
- 69 Macfarlane D. E, Mills D. C. B. 1975; The effects of ATP on platelets: Evidence against the centrol role of released ADP in primary aggregation. Blood 46: 309.
- 70 Macfarlane D. E, Stibbe J, Kirby E. P, Zucker M. B, Grant R. A, McPherson J. 1975; A method for assaying von Willebrand factor (ristocetin cofactor). Thrombosis et Diathesis Haemorrhagica 34: 306.
- 71 Macfarlane R. G, Biggs R, Bidwell E. 1954; Bovine antihaemophilic globulin in the treatment of haemophilia. Lancet I: 1316.
- 72 Mannucci P. M, Meyer D, Ruggeri Z. M, Koutts J, Ciavarella N, Lavergne J. M. 1976; Precipitating antibodies in von Willebrand’s disease. Nature 262: 141.
- 73 Massini P, Metcalf L. C, Naf U, Luscher E. F. 1974; Induction of aggregation and of the release reaction in human platelets by polylysine. Haemostasis 3: 8.
- 74 McKee P. A, Andersen J. C, Switzer M. E. 1975; Molecular structural studies of human factor VIII. Annals of the New York Academy of Sciences 240: 8.
- 75 Mester L, Szabados L, Halmos T, Mester M, Guinebault P. R, Platel A. 1973 The role sialic add in the mechanism of platelet aggregation. In: Erythrocytes, Thrombocytes, Leukocytes. (eds.) Gerlach E. et al. 257.
- 76 Meyer C, Jenkins C. S. P, Larrieu M. J. 1975. Willebrand factor and ristocetin-induced platelet aggregation. In: Platelets. (ed.) Ulutin O. N. Excerpta Medica; Amsterdam: 139.
- 77 Meyer D, Jenkins C. S. P, Dreyfus M, Larrieu M. J. 1973; Experimental model for von Willebrand’s disease. Nature 243: 293.
- 78 Muraki H, Watanabe K, Ando Y, Toyama K, Hasegawa M. 1977; Reduction of surface negative charge in human platelets by ristocetin. Thrombosis and Haemostasis 38: 69 (abstract).
- 79 Nachman R. L, Hubbard A, Ferris B. 1973; Iodination of the human platelet membrane. Studies of the major surface glycoprotein. Journal of Biological Chemistry 248: 2928.
- 80 Nachman R. L, Jaffe E. A. 1975; Subcellular platelet factor VIII antigen and von Willebrand factor. Journal of Experimental Medicine 141: 1101.
- 81 Nachman R. L, Jaffe E. A, Weksler B. B. 1977; Immunoinhibition of ristocetin-induced platelet aggregation. Journal of Clinical Investigation 59: 143.
- 82 Newman J, Harris R. B, Johnson A. J. 1976; Molecular weights of antihaemophilic factor and von Willebrand factor proteins in human plasma. Nature 263: 612.
- 83 Nilsson I. M, Blomback M, Blomback B. 1960; The use of human antihaemophilic globulins (Fraction I–0) in haemophilia A and in von Willebrand’s disease. Acta Haematologica 24: 116.
- 84 Nurden A. T. 1977; A peripheral high molecular weight glycoprotein located at the surface of human platelets. Experientia 35: 331.
- 85 Nurden A. T, Caen J. P. 1975; Specific roles for platelet surface glycoproteins in platelet function. Nature 225: 720.
- 86 Nurden A. T, Caen J. P. 1976; Role of surface glycoproteins in human platelet function. Thrombosis and Haemostasis 35: 139.
- 87 Okamura T, Jamieson G. 1976; Platelet glycocalicin. I. Orientation of glycoproteins of the human platelet surface. Journal of Biological Chemistry 251: 5944.
- 88 Okamura T, Jamieson G. A. 1976; Platelet glycocalicin: A single receptor for platelet aggregation induced by thrombin or ristocetin. Thrombosis Research 8: 701.
- 89 Okamura T, Lombart C, Jamieson G. A. 1976; Platelet glycocalicin. II. Purification and characterization. Journal of Biological Chemistry 251: 5950.
- 90 Olson J. C, Brockway W. J, Fass D. N, Magnuson M. A, Bowie E. J. W. 1975; Evaluation of ristocetin-Willebrand Factor assay and ristocetin-induced platelet aggregation. American Journal of Clinical Pathology 63: 210.
- 91 Olson J. D, Fass D. N, Bowie E. J. W, Mann K. G. 1973; Ristocetin-induced aggregation of gel filtered platelets. A study of von Willebrand’s disease and the effects of aspirin. Thrombosis Research 3: 501.
- 92 Østvold A. C, Lindberg M. E, Solum N. O, Holmsen H. 1975; Adenine nucleotide metabolism during the aggregation of human platelets by bovine factor VIII. Haemostasis 4: 3.
- 93 Peake I. R, Bloom A. L. 1977; Abnormal Factor VIII related antigen (FVIIIRAG) in von Willebrand’s disease (VWD): Decreased precipitation by concanavalin A. Thrombosis and Haemostasis 37: 361.
- 94 Peake I. R, Bloom A. L, Giddings J. C. 1974; Inherited variants of Factor VIII-related protein in von Willebrand’s disease. New England Journal of Medicine 291: 113.
- 95 Pekcelen Y, Inceman S. 1976; Heparin and ristocetin-induced platelet aggregation. Thrombosis and Haemostasis 35: 485.
- 96 Perkins H. R, Nieto M. 1974; The chemical basis for the action of the vancomycin group of antibiotics. Annals of New York Academy of Sciences 135: 348.
- 97 Philip J. E, Schenck J. R, Hargie M. P, Holper J. C, Grundy W. E. 1960 61 The increased activity of ristocetin A and B following acid hydrolysis. Antimicrobial Agents Annual. 10.
- 98 Phillips D. R. 1974; Effect of trypsin on the exposed polypeptides and glycoproteins in the human platelet membrane. Biochemistry 11: 4582.
- 99 Phillips D. R, Agin P. P. 1977; Platelet plasma membrane glycoproteins. Evidence for the presence of nonequivalent disulfide bonds using nonreduced-reduced two-dimensional gel electrophoresis. Journal of Biological Chemistry 252: 2121.
- 100 Piovella F, Ascari E, Sitar G. M, Malamini G. D, Cattaneo G, Magiulo E, Storti E. 1974; Immunofluorescent detection of factor VIII-related antigen in human platelets and megakaryocytes. Haemostasis 3: 288.
- 101 Roper P, Peterson D. M, Moake J. L. 1975. Vancomycin inhibition of platelet aggregation induced by ristocetin, collagen and ADP. Proceedings of the 18th Annual Meeting. American Society of Hematology; 201.
- 102 Salzman E. W. 1963; Measurement of platelet adhesiveness. Journal of Laboratory and Clinical Medicine 62: 724.
- 103 Sarji K. E, Stratton R. D, Wagner R. H, Brinkhous K. M. 1974; Nature of von Willebrand factor: A new assay and a specific inhibitor. Proceedings of the National Academy of Sciences (U.S.) 71: 2937.
- 104 Schneider-Trip M, Wanders R, TenCate I. W, Jenkins C. 1975; Interaction of fibrinogen and Factor VIII with human platelets. Thrombosis et Diathesis Haemorrhagica 34: 581 (abstract).
- 105 Shearn S. A. M, Giddings J. C, Peake I. R, Bloom A. L. 1974; A comparison of five different rabbit antisera to Factor VIII and the demonstration of a Factor VIII related antigen in normal and von Willebrand’s disease platelets. Thrombosis Research 5: 585.
- 106 Sodetz J. M, Pizzo S. V, McKee P. A. 1977; The relationship of sialic acid to the function and in vivo survival time of human F-VIII. Federation Proceedings 36: 675 (abstract).
- 107 Solum N. O. 1968; Aggregation of human platelets by bovine platelet fibrinogen. Scandinavian Journal of Haematology 5: 474.
- 108 Solum N. O, Hagen I, Peterka M. 1977; Human platelet glycoproteins. Further evidence that the “GPI band” from whole platelets contains three different polypeptides, one of which may be involved in the interaction between platelets and Factor VIII. Thrombosis Research 10: 71.
- 109 Solum N. O, Hagen L, Peterka M, Gjemdal T. 1977; Absence of the 145,000 molecular weight, soluble platelet glycoprotein— lack of platelet agglutination. Thrombosis and Haemostasis 38: 233 (abstract).
- 110 Stibbe J, Kirby E. P. 1976; The influence of Haemaccel, fibrinogen and albumin on ristocetin-induced platelet aggregation. Relevance to the quantitative measurement of the ristocetin cofactor. Thrombosis Research 8: 151.
- 111 Sultan Y, Jeanneau C, Lamaziere J. 1976; Absence of Factor VIII-related antigen penetration and binding to von Willebrand platelets after transfusion. Circulation 53 (Suppl. 02) 115 (abstract).
- 112 Sultan Y, Simeon J, Caen J. P. 1975; Electrophoretic heterogeneity of normal Factor VIII/von Willebrand protein and abnormal electrophoretic mobility in patients with von Willebrand’s disease. Journal of Laboratory and Clinical Medicine 87: 185.
- 113 Switzer M. E, McKee P. A. 1976; Studies on human antihemophilic factor. Evidence for a covalently linked subunit structure. Journal of Clinical Investigation 57: 925.
- 114 Tangen D, Karlstam B, Bygdeman S. 1977; Effects of lectins on blood platelets from various species. Thrombosis and Haemostasis 38: 155 (abstract).
- 115 Tobelem G, Levy-Toledano S, Bredoux R, Michel H, Nurden A, Caen J, Degos L. 1976; New approach to determination of specific functions of platelet membrane sites. Nature 263: 427.
- 116 Tollefsen D. M, Feagler J. R, Majerus P. W. 1974; Induction of the platelet release reaction by phytohemagglutinin. Journal of Clinical Investigation 53: 211.
- 117 Ts’ao C. H, Green D, Rossi E. C. 1973; Ultrastructure of ristocetin aggregated normal human platelets: Tortuous boundaries and swollen granules. Scandinavian Journal of Haematology 11: 287.
- 118 Ts’ao C. H, Green D, Rossi E. C. 1975; Some factors affecting fibrinogen precipitation by ristocetin: Ultrastructure of precipitates. Blood 45: 621.
- 119 Tschopp T, Weiss H. J, Baumgartner H. R. 1974; Decreased adhesion of platelets to subendothelium in von Willebrand’s disease. Journal of Laboratory and Clinical Medicine 83: 296.
- 120 Vermylen J, Bottecchia D, Szpilman H. 1976; Factor VIII and human platelet aggregation. III. Further studies on aggregation of human platelets by neuraminidase-treated human Factor VIII. British Journal of Haematology 34: 321.
- 121 Vermylen J, de Gaetano G, Donati M. B, Verstraete M. 1974; Platelet aggregating activity in neuraminidase-treated human cryoprecipitates: Its correlation with Factor VIII-related antigen. British Journal of Haematology 26: 645.
- 122 Vermylen J, Donati M. B, de Gaetano G, Verstraete M. 1973; Aggregation of human platelets by bovine or human Factor VIII: Role of carbohydrate side chains. Nature 244: 167.
- 123 von Willebrand E. A, Jürgens R. 1933; Über eine neue Bluterkrankheit, die konstitutionelle Thrombopathie. Klinische Wochenschrift 12: 414.
- 124 Walsh P. N, Mills D. C. B, Pareti F. L, Stewart G. J, Macfarlane D. E, Johnson M. M, Egan J. J. 1975; Hereditary giant platelet syndrome. Absence of collagen-induced coagulant activity and deficiency of Factor XI binding to platelets. British Journal of Haematology 29: 639.
- 125 Weiss H. J. 1974; Relation of von Willebrand factor to bleeding time. New England Journal of Medicine 291: 420.
- 126 Weiss H. J, Baumgartner H. B, Tschopp T. B, Tuitto V. T, Cohen D. 1976; Impaired adhesion of platelets to subendothelium in von Willebrand’s disease is corrected by Factor VIII. Blood 48: 1009 (abstract).
- 127 Weiss H. J, Hoyer L. W, Rickles F. R, Varma A, Rogers J. 1973; Quantitative assay of a plasma factor deficient in von Willebrand’s disease that is necessary for platelet aggregation. Relationship to Factor VIII procoagulant activity and antigen content. Journal of Clinical Investigation 52: 2708.
- 128 Weiss H. J, Rogers J, Brand H. 1973; Defective ristocetin induced platelet aggregation in von Willebrand’s disease and its correction by Factor VIII. Journal of Clinical Investigation 52: 2697.
- 129 Weiss H. J, Rogers J, Brand H. 1973; Properties of platelet retention (von Willebrand) factor and its similarity to the antihemophilic factor (AHF). Blood 41: 809.
- 130 Weiss H. J, Tschopp T. B, Baumgartner H. R, Sussman J.J, Johnson M. M, Egan J. J. 1974; Decreased adhesion of giant (Bemard-Soulier) platelets to subendothelium. Further implications of the role of the von Willebrand factor in hemostasis. American Journal of Medicine 57: 920.
- 131 Zimmerman T. S, Abildgaard C. F, Edgington T. S. 1976; Multiple molecular forms of factor VIII-related antigen in normal plasma: Relationship to molecular abnormalities in von Willebrand’s disease. Clinical Research 24: 444 A (abstract).
- 132 Zimmerman T. S, Edgington T. S. 1973; Factor VIII coagulant activity and Factor VIII-like antigen: Independent molecular entities. Journal of Experimental Medicine 138: 1015.
- 133 Zimmerman T. S, Kimball J. R, Edgington T. S, Abildgaard C. F. 1977; Multiple molecular forms of Factor VIII antigen in normal individuals and von Willebrand’s disease patients. Thrombosis and Haemostasis 38: 54 (abstract).
- 134 Zimmerman T. S, Ratnoff O. D, Powell A. E. 1971; Immunologic differentiation of classic hemophilia (Factor VIII deficiency) and von Willebrand’s disease. Journal of Clinical Investigation 50: 244.
- 135 Zimmermann T. S, Roberts J, Edgington T. S. 1975; Factor VIII-related antigen: Multiple molecular forms in human plasma. Proceedings of the National Academy of Sciences (U.S.) 72: 5121.
- 136 Zucker M. B, Kim S. J, McPherson J, Grant R. A. 1977; Binding of factor VIII to platelets in the presence of ristocetin. British Journal of Haematology 35: 535.
- 137 Zucker M. B, McPherson J, Kim S. J, McDonald V. E, Taylor D, Johnson A. J, Barlow G. H. 1975; Interaction of ristocetin (R), von Willebrand Factor (vWF), Factor VIII clotting activity (VIIIc) and platelets. Thrombosis et Diathesis Haemorrhagica 34: 582 (abstract).