Originalarbeiten – Original Articles – Travaux Originaux
Schattauer GmbH
Comparison between a Direct and an Indirect Method for Determining Plasminogen
Ulla Hedner
1
Coagulation Laboratory, University of Lund, Allmänna Sjukhuset, Malmö, Sweden
,
Inga Marie Nilsson
1
Coagulation Laboratory, University of Lund, Allmänna Sjukhuset, Malmö, Sweden
› InstitutsangabenThis investigation was supported by grants from the Swedish Medical Research Council (B70-19X-87-06C) and the Faculty of Medicine, University of Lund.
A caseinolytic method for plasminogen determination using 30% ammonium sulphate to remove the inhibitors was compared with an immunochemical method in 44 apparently healthy individuals, 25 pregnant women in the third trimester, 24 patients with different liver diseases, 20 patients receiving thrombolytic therapy, 7 patients with septicemia and 9 foetuses obtained by induced legal abortion. The correlation found was strong and the regression line was found to pass near origo, indicating that the two methods measured, the same substance.
Both methods gave high plasminogen values in pregnant women and low values in patients receiving thrombolytic therapy and in foetuses.
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