Summary
Methods are described for measuring fibrinolytic activity in the rat. These include
dilute blood clot lysis, euglobulin clot lysis, a fibrin plate assay with euglobulin
solutions, and an accelerated whole blood clot lysis technique in which limited fibrinolysis
is induced with urokinase. In addition, methods have been worked out for the estimation
of four plasma components closely involved in fibrinolysis: fibrinogen, factor XIII,
plasma inhibitors and fibrin degradation products. The sensitivity and validity of
the assays were tested by studying their capacity to detect changes resulting from
the administration of eledoisin, Neohydrin and turpentine.
