Thromb Haemost 1971; 26(02): 407-410
DOI: 10.1055/s-0038-1653690
Originalarbeiten – Original Articles – Travaux Originaux
Schattauer GmbH

Experimental Arterial Thrombosis in Rats with Continuous Registration

J Hladovec
1   Institute for Cardiovascular Research, Praha, ČSSR
› Author Affiliations
Further Information

Publication History

Publication Date:
28 June 2018 (online)

Summary

The author describes a method of experimental arterial thrombosis in rats suitable for testing drugs with suggested antithrombotic effects. The thrombosis was provoked by electric current in the carotid artery and continuously registered by a contact thermometer.

 
  • References

  • 1 Cowan C. R, Monhliouse F. C. Studies on electrically induced thrombosis and related phenomena. Canad. J. Physiol. Pharmacol 44: 881 1966;
  • 2 Duval D. L, Didisheim P. et al. Experimental thrombosis: description of a method. Mayo Clin. Proc 45: 388 1970;
  • 3 Henry R. L. Methods for inducing experimental thrombosis. Angiology 13: 554 1962;
  • 4 Hladovec J, Mansfeld V. Konduktometrische Registrierung der Blutgerinnung in vivo. Blut 05: 282 1959;
  • 5 Lamb J. C, Isaacs J. P. et al. Electrical thrombosis of blood vessels. A voltage-dependent phenomenon. Amer. J. Physiol 208: 1006 1965;
  • 6 Reber K. A device for the production of well-defined lesions of mesenteric blood vessels with resulting platelet thrombi. Thrombos. Diathes. haemorrh. (Stuttg) 15: 471 1966;
  • 7 Weisse A. B. The fate of experimentally induced coronary artery thrombosis. Clin. Res 14: 475 1966;