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Thromb Haemost 1970; 23(03): 417-422
DOI: 10.1055/s-0038-1654067
Originalarbeiten – Original Articles – Travaux Originaux
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Activation of Hageman Factor by α-Adrenergic Stimulation

D. G McKay M. D.,
1   Department of Pathology University of California School of Medicine San Francisco General Hospital 1001 Potrero Avenue San Francisco, California 94110
,
J.-G Latour Ph. D.
1   Department of Pathology University of California School of Medicine San Francisco General Hospital 1001 Potrero Avenue San Francisco, California 94110
,
Mary H. Parrish B. S.
1   Department of Pathology University of California School of Medicine San Francisco General Hospital 1001 Potrero Avenue San Francisco, California 94110
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Publikationsdatum:
27. Juni 2018 (online)

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Summary

The infusion of epinephrine in high doses produces disseminated intravascular coagulation by activation of Hageman factor. The effect is blocked by phenoxybenz-amine and is therefore due to stimulation of α-adrenergic receptor sites.

 

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