Thrombosis and Haemostasis, Table of Contents Thromb Haemost 1970; 24(01/02): 304-307DOI: 10.1055/s-0038-1654237 Vorläufige Mitteilungen - Preliminary Reports - Communications Préliminaires Schattauer GmbH Platelet Adhesiveness, Aggregation and Fibrinolysis after the Oral Administration of the Contraceptive “Lyndiol” R Farbiszewski 1 Division of Biochemistry and Department of Obstetrics and Gynecology, District Hospital, Bialystok, Poland , T Kurowska 1 Division of Biochemistry and Department of Obstetrics and Gynecology, District Hospital, Bialystok, Poland › Author Affiliations Recommend Article Abstract Buy Article Summary The adhesiveness and aggregation of platelets in plasma of women treated with “Lyndiol”, an anticonceptive agent, were investigated. An increase of adhesiveness and enhancement of platelet aggregation induced by ADP and thrombin was observed. The pathophysiological significance of the described changes is briefly discussed. Full Text References References 1 Adlersberg D. Hormonal influences on the serum lipids. Amer. J. Med 195: 769 1957; 2 Arcangelli A. Sindromi emmorragiche e endocrinopatie: ricerce sperimentali. 3. Azione degli estrogeni e del progesterone si alcuni fattori emocoagulativi, piastrinici e vasculo tescutali. Rass. Neurol, veg 18: 840 1964; 3 Bielecki M, Wisniewski L, Jablonski J, Jezuita J, Stojak T. O korelacji pomiedzy zjawiskami hormonalnymi i ukladem krzepniecia i fibrynolizy u dojrzewajacych chlopcow. Endokr. pol 03: 315 1967; 4 Bolton C. H, Hampton J. R, Mitchell J. R. A. Nature of the transferable factor which causes abnormal platelet behaviour in vascular disease. Lancet II: 1101 1967; 5 Bolton C. H, Hampton J. R, Mitchell J. R. A. Effect of oral contraceptive agents on platelets and plasmaphospholipids. Lancet I: 1336 1968; 6 Brakman P, Astrup T. Effects of female hormones, used as contraceptives on the fibrinolytic system in blood. Lancet II: 10 1964; 7 Gaspary E. A, Peberdy M. Oral conception and blood platelet adhesiveness. Lancet I: 1142 1965; 8 Croizat P, Planchu M, Favre-Gilly J, Morel P. Troubles endocriniens et syndromes hémorragiques. Sang 23: 251 1952; 9 Elkeles R. S, Hampton J. R, Mitchell J. R. A. Effect of estrogens on human platelet behaviour. Lancet II: 315 1968; 10 Farbiszewski R, Worowski K. The effect of modified beta-lipoproteins on adhesiveness and on aggregation of blood platelets. J. atheroscler. Res 09: 339 1969; 11 Gaertner H, Lisiewicz J. Inaktywacja thrombiny w surowicy zdrowych doroslych osöb. Postepy Hig. Med. dosw 14: 691 1960; 12 Kowalski E, Kopec M, Niewiarowski S. An evaluation of the euglobulin method for the determination of fibrinolysis. J. clin. Path 12: 215 1959; 13 Musiatowicz J, Bielecki M, Jaszkowska J, Wisniewski L, Wielkopolan J. Aktywnosc fibrynolityczna osocza w czasie stosowania stilbestrolu. Pol. Tyg. lek 21: 127 1966; 14 Niewiarowski S, Thomas D. Platelet aggregation by ADP and thrombin. Nature (Lond) 212: 1544 1966; 15 Oliver M. F, Boyd O. S. The effect of estrogen on the plasma lipids in coronary disease. Amer. Heart J 47: 348 1954; 16 Stormoken H, Riise ALuna, Rorvik T. O. Platelet adhesiveness to glass beads; methodological investigation using automatic platelet caunting. Scand. J. clin. Lab. Invest. 17, Suppl 84: 183 1965; 17 Wisniewski L. Zachowanie sie ukladu krzepniecia i fibrynolizy u pokwitajacych dziewczat. Ginek. pol 36: 1179 1965;
