The Investigation of a Patient with an Unusual Coagulation Defect

Emiliano L. Gomes; Therezinha R. Calicchio; Rosemary Biggs

doi:10.1055/s-0038-1654563

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1961; 6(02): 308-316
DOI: 10.1055/s-0038-1654563

Originalarbeiten — Original Articles — Travaux Originaux

Schattauer GmbH

The Investigation of a Patient with an Unusual Coagulation Defect

Emiliano L. Gomes

¹“Socorro Doenças do Sangue”, 5a Cad. Clin. Med., Fac. Nac. Med., Rio de Janeiro, Brazil Blood Coagulation Research Unit, Churchill Hospital, Oxford

,

Therezinha R. Calicchio

¹“Socorro Doenças do Sangue”, 5a Cad. Clin. Med., Fac. Nac. Med., Rio de Janeiro, Brazil Blood Coagulation Research Unit, Churchill Hospital, Oxford

,

Rosemary Biggs

¹“Socorro Doenças do Sangue”, 5a Cad. Clin. Med., Fac. Nac. Med., Rio de Janeiro, Brazil Blood Coagulation Research Unit, Churchill Hospital, Oxford

› Author Affiliations

Abstract

Summary

1. The coagulation defect of a patient whose blood contains an inhibitor is described.

2. The inhibitor lengthens the clotting time of plasma in the presence of weak thromboplastin and also interferes with the mechanism of glass contact activation.

3. It is suggested that the inhibitor is similar to those which occur in the blood of patients with disseminated lupus erythematosus.

Full Text

References

References
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