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Thromb Haemost 1961; 6(02): 381-385
DOI: 10.1055/s-0038-1654569
DOI: 10.1055/s-0038-1654569
Vorläufige Mitteilungen — Preliminary Reports — Communications Préliminaires
The Influence of Some Anticoagulants and Fibrinolytic Substances on Mice Fibroblasts (Strain L) in Tissue Culture
Further Information
Publication History
Publication Date:
12 July 2018 (online)
Summary
The action of some anticoagulants and fibrinolytic substances on the culture of mice fibroblasts is described. Actase and streptokinase show a relatively high toxicity. Beta-heparins are more toxic than alpha-heparins. For pentosans the cytotoxic action is inversely proportional to the molecular weight. Marcoumar is more toxic than coumarin without anticoagulant activity. Variations of the concentration of factors VII, IX and X are of no importance for the cells. Cells 4 hours after explantation are not basically more sensitive than cells 24 hours after explantation.
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References
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