Thromb Haemost 1965; 14(03/04): 500-507
DOI: 10.1055/s-0038-1654886
Originalarbeiten — Original Articles — Travaux Originaux
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Activation of Fibrinolysis and of Plasma-Kinin System during Venostasis*

K Buluk
1   Department of General and Experimental Pathology Medical School, Bialystok, Poland (Head of Department: Prof. Dr. Karol Buluk)
,
M Malofiejew
1   Department of General and Experimental Pathology Medical School, Bialystok, Poland (Head of Department: Prof. Dr. Karol Buluk)
,
Maria Czokalo
1   Department of General and Experimental Pathology Medical School, Bialystok, Poland (Head of Department: Prof. Dr. Karol Buluk)
› Institutsangaben

This investigation was supported by a grant from the Theme Panel “Pathogenesis of Shock” Section of Medical Sciences, Polish Academy of Sciences.
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Publikationsdatum:
24. Juli 2018 (online)

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Summary

In the plasma of stasis blood, fibrinolytic activity increases as a result of the enrichment of this blood by fibrinolysis activators of tissue origin. With the increase in fibrinolytic activity an increase in kallikrein and a temporary release of plasma kinin occurs. Plasma kallikrein, activated in the stasis blood through fibrinolysis activation on application of a manometric cuff retains its activity and may play some role in the lowering of blood pressure when the cuff is removed.