Thrombosis and Haemostasis, Table of Contents Thromb Haemost 1961; 05(01): 074-086DOI: 10.1055/s-0038-1654904 Originalarbeiten – Original Article – Travaux Originaux Schattauer GmbH Observations on Thromboplastin Generations Using Platelet Suspensions Prepared by a Simplified Method E Davidson 1 Department of Medicine, University of Cambridge , S Tomlin 1 Department of Medicine, University of Cambridge › Author Affiliations Recommend Article Abstract Buy Article Summary A simplified method of preparing platelet suspensions is described. The efficiency and reproducibility of results using these suspensions compares favourably with those of standard platelet suspensions and brain extract. In comparing the thromboplastin generation and the thromboplastin screening tests no important practical differences are noted. The use of simplified platelet suspensions is recommended for routine use in the thromboplastin screening test. Full Text References References Barkhan P. Thromboplastin formation in human blood with special reference to platelet and lipid factors. Ph. D. Thesis. University of Cambridge; 1957 Biggs R, Douglas A. S. The thromboplastin generation test. J. clin. Path. 06: 23 1953; Biggs R, Veling J. E, Richards G. The assay of antihaemophilic globulin activity. Brit. J. Haemat. 01: 20 1955; Biggs R, Macfarlane R. G. Human Blood Coagulation and its Disorders. Blackwell Scientific Publications; Oxford: 1957 Hicks N. D, Pitney W. R. A rapid screening test for disorders of thromboplastin formation. Brit. J. Haemat. 02: 227 1957; Hjort P, Rapaport S. J, Owren P. A. Evidence that platelet accelerator (platelet factor 1) is adsorbed plasma proaccelerin. Blood 10: 1139 1955; Mann F. D. The reactivity of haemophiliac plasma to platelet thromboplastin. J. Lab. clin. Med. 48: 51 1956; Quick A. J. The thromboplastinogen activity time (TAT) test. Thromb. Diath. haem. 01: 9 1957; Raccuglia G, Duff I. F, Bethell F. H. The detection of defects in the first stage of coagulation. J. Lab. clin. Med. 53: 789 1959; Seaman A. J, Karlsen K. M. Influence of serum incubation conditions on asolectin thromboplastin generation results. Thromb. Diath. haem. 04: 83 1960; Sharp A. A. The assessment of platelet function. Postgrad. Med. J. 35: 506 1959; Verstraete M, Vandenbroucke J. The thromboplastin generation test. Acta med. Scand. 155: 37 1956; Wolf P. Lipid extracts of platelets and brain as substitutes for platelets in coagulation tests. Brit. J. Haemat. 02: 375 1956;
