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Hamostaseologie 1985; 05(04): 134-138
DOI: 10.1055/s-0038-1655115
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Protein-C-Mangel

I. Pabinger-Fasching
1   I. Medizinische Universitätsklinik (Vorstand: Prof. Dr. Dr. h. c. E. Deutsch), Abteilung für Hämatologie und Blutgerinnung, Wien
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Publikationsdatum:
22. Juni 2018 (online)

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  • LITERATUR

  • 1 Stenflo J. A new vitamin K dependent protein. J. Biol. Chem 251: 355-363 1976;
    PubMedSuche in Google Scholar
  • 2 Kisiel W. Human protein C: Isolation, characterization and mechanism of activation. J. Clin. Invest 64: 761-769 1979;
    CrossrefPubMedSuche in Google Scholar
  • 3 Esmon C. T, Stenflo J, Suttie J. W. A new vitamin K dependent protein. J. Biol. Chem 251: 3052-3056 1975;
    PubMedSuche in Google Scholar
  • 4 Mammen J. F, Thomas W. R, Seegers W. H. Activation of purified prothrombin to autoprothrombin II-A. Thromb. Diath. Haemorrh 05: 218-250 1960;
    PubMedSuche in Google Scholar
  • 5 Seegers W. H, McCoy E. L, Groben H. D, Sakuragawa N, Agrawal B. B. L. Purification and some properties of autoprothrombin II-A: An anticoagulant perhaps also related to fibrinolysis. Thromb. Res 01: 443-460 1972;
    CrossrefPubMedSuche in Google Scholar
  • 6 Dahlbäck B, Stenflo J. Inhibitory effect of activated protein C on activation of prothrombin by platelet-bound cofactor Xa. Eur. J. Biochem 107: 331-335 1980;
    PubMedSuche in Google Scholar
  • 7 Dahlbäck B, Stenflo J. Inhibitory effect of activated protein C on activation of prothrombin by platelet-bound cofactor Xa. Eur. J. Biochem 107: 331-335 1980;
    PubMedSuche in Google Scholar
  • 8 Esmon C. T, Owen W. G. Identification of an endothelial cell cofactor for thrombin catalized activation of protein C. Proc. Natl. Acad. SCi. USA 78: 2245-2252 1981;
    PubMedSuche in Google Scholar
  • 9 Esmon C. T, Esmon N. L, Harris K. W. Complex formation between thrombomodulin inhibits both thrombin-catalyzed fibrin formation and F V activation. J. Biol. Chem 257: 7944-7947 1982;
    PubMedSuche in Google Scholar
  • 10 Esmon N. L, Roger C. C, Esmon C. T. Thrombomodulin blocks the ability of thrombin to activate platelets. J. Biol. Chem 258: 1238-1242 1983;
    PubMedSuche in Google Scholar
  • 11 Marlar R. A, Kleiss A. J, Griffin J. H. Mechanism of action of activated protein C, a thrombin dependent anticoagulant enzyme. Blood 59: 1062-1072 1982;
    PubMedSuche in Google Scholar
  • 12 Suzuki K, Stenflo J, Dahlbäck B, Teodorsson B. Inactivation of human coagulation factor V by activated protein C.J. Biol. Chem 258: 1914-1920 1983;
    PubMedSuche in Google Scholar
  • 13 Fulcher C. A, Gardiner E. J, Griffin J. H, Zimmermann T. S. Proteolytic inactivation of human F VIII procoagulant protein by activated protein C and its analogy with F.V. Blood 63: 486-489 1984;
    PubMedSuche in Google Scholar
  • 14 Comp P. C, Esmon C. T. Activated protein C inhibits platelet prothrombin converting activity. Blood 54: 1272-1281 1979;
    PubMedSuche in Google Scholar
  • 15 Dahlbäck B, Stenflo J. Inhibitory effect of activated protein C on activation of prothrombin by platelet-bound cofactor Xa. Eur. J. Biochem 107: 331-335 1980;
    PubMedSuche in Google Scholar
  • 16 Fletcher B. T, Lockhart M. S. A new function for activated protein C: Activated protein C prevents inhibition of plasminogen activators by release from mononuclear leukocytes - platelet suspensions stimulated by phorbol diester. Thromb. Res 37: 155-164 1985;
    CrossrefPubMedSuche in Google Scholar
  • 17 Fletcher B. T, Lockhart M. S. Whole blood clot lysis: In vitro modulation by activated protein C. Thromb. Res 37: 639-649 1985;
    CrossrefPubMedSuche in Google Scholar
  • 18 Comp P. C, Esmon C. T. Initiation of clot lysis in plasma by activated protein C. Circulation 57/58 (Suppl. II): 210 1978;
    PubMedSuche in Google Scholar
  • 19 Comp P. C, Esmon C. T. Generation of in vivo fibrinolytic activity by infusion of activated protein C into dogs. Circulation 62 (Suppl. Ill): 334 1980;
    PubMedSuche in Google Scholar
  • 20 Walker F. J. Regulation of activated protein C by a new protein. A possible function for bovine protein S.J. Biol. Chem 255: 5521-5524 1980;
    PubMedSuche in Google Scholar
  • 21 Schwarz H. P, Fischer M, Hoppmeier P, Batard M. A, Griffin J. H. Plasma protein S deficiency in familial thrombotic disease. Blood 64: 1297-1300 1984;
    PubMedSuche in Google Scholar
  • 22 Comp P. C, Esmon C. T. Recurrent venous thromboembolism in patients with a partial deficiency of protein S.N. Engl. J. Med 311: 1525-1528 1984;
    CrossrefPubMedSuche in Google Scholar
  • 23 Broekmans A. W, Bertina R. M, Reinalda-Poot J, Engesser L, Muller H. P, Leeuw J. A, Michiels J. J, Brommer E. J. P, Briet E. Hereditary protein S deficiency and venous thrombo-embolism. Thromb. Haemost. (in press
    PubMed
  • 24 Marlar R. A, Griffin J. H. Deficiency of protein C inhibitor in combined factor V/VIII deficiency disease. J. Clin. Invest 66: 1186-1189 1980;
    CrossrefPubMedSuche in Google Scholar
  • 25 Griffin J. H, Evatt B, Zimmermann T. S, Kleiss A. J, Wideman C. Deficiency of protein C in congenital thrombotic disease. J. Clin. Invest 68: 1370-1373 1981;
    CrossrefPubMedSuche in Google Scholar
  • 26 Vikydal R, Korninger C, Kyrie P. A, Niessner H, Pabinger I, Thaler E, Lechner K. The prevalence of hereditary antithrombin Ill-deficiency in patients with a history of venous thromboembolism. Thromb. Haemostas.. 1985 in press
    PubMedSuche in Google Scholar
  • 27 Broekmanns A. W, Yeltkamp J. J, Bertina R. M. Congenital protein C deficiency and venous thromboembolism. A study in three Dutch families. N. Engl. J. Med 309: 340-344 1983;
    PubMedSuche in Google Scholar
  • 28 Pabinger-Fasching I, Bertina R. M, Lechner K, Niessner H, Korninger C. Protein C deficiency in two Austrian families. Thromb. Haemost 50: 810-813 1983;
    Thieme ConnectPubMedSuche in Google Scholar
  • 29 Horellou M. H, Conard J, Bertina R. M, Samama M. Congenital protein C deficiency and thrombotic disease in nine French families. Brit. Med. J 289: 1285-1287 1984;
    CrossrefPubMedSuche in Google Scholar
  • 30 Boyer C, Rothschild C, Wolf M, Amiral J, Meyer D, Larrieu M. J. A new method for the estimation of protein C by ELISA. Thromb. Res 36: 579-589 1984;
    CrossrefPubMedSuche in Google Scholar
  • 31 Bertina R. M. A, Broekmanns W, van Es-Krommenhoek C, van Wijngaarden A. The use of functional and immunological assay for plasma protein C in the study of the heterogeneity of congenital protein C deficiency. Thromb. Haemost 51: 1-5 1984;
    PubMedSuche in Google Scholar
  • 32 Sala N, Owen W. G, Collen D. A functional assay of protein C in human plasma. Blood 63: 671-675 1984;
    PubMedSuche in Google Scholar
  • 33 Francis R. B, Patch M. J. A functional assay for protein C in human plasma. Thromb. Res 32: 605-613 1983;
    CrossrefPubMedSuche in Google Scholar
  • 34 Comp P. C, Nixon R. R, Esmon C. T. Determination of functional levels of protein C, an antithrombotic protein, using thrombin-thrombomodulin complex. Blood 63: 15-21 1984;
    PubMedSuche in Google Scholar
  • 35 Mannucci P. M, Vigano S. Deficiencies of protein C, an inhibitor of blood coagulation. Lancet II: 463-466 1982;
    PubMedSuche in Google Scholar
  • 36 Polack B, Pouzol P, Amiral J, Kolo-die L. Protein C level at birth. Thromb. Haemost 52: 188-190 1984;
    Thieme ConnectPubMedSuche in Google Scholar
  • 37 Mannucci P. M, Vigano S, Bottasso B, Candotti G, Bozzetti P, Rossi E, Pardi G. Protein C. Antigen during pregnancy, delivery and puerperium. Throm. Haemost 52: 217 1984;
    PubMedSuche in Google Scholar
  • 38 Vikydal R, Korninger C, Kyrie P. A, Niessner H, Pabinger I, Thaler E, Lechner K. The prevalence of hereditary antithrombin Ill-deficiency in patients with a history of venous thromboembolism. Thromb. Haemostas.. 1985 in press
    PubMedSuche in Google Scholar
  • 39 Estelles S, Garcia-Plaza I, Dasi A, Aznar J, Duart M, Sanz G, Perez-Requejo J. L, Espana F, Jimenez C, Abele-do G. Severe inherited »homozygous« protein C deficiency in a newborn infant. Thromb. Haemost 52: 53-56 1984;
    PubMedSuche in Google Scholar
  • 40 Marciniak E, Wilson H. D, Marlar R. A. Neonatal purpura fulminans: A genetic disorder related to the absence of protein C in blood. Blood 65: 15-20 1985;
    PubMedSuche in Google Scholar
  • 41 Vikydal R, Korninger C, Kyrie P. A, Niessner H, Pabinger I, Thaler E, Lechner K. The prevalence of hereditary antithrombin Ill-deficiency in patients with a history of venous thromboembolism. Thromb. Haemostas.. 1985 in press
    PubMedSuche in Google Scholar
  • 42 Thaler E, Lechner K. Antithrombin III deficiency and thromboembolism. Clin. Haemat 10: 369-390 1981;
    PubMedSuche in Google Scholar
  • 43 Vikydal R, Korninger C, Kyrie P. A, Niessner H, Pabinger I, Thaler E, Lechner K. The prevalence of hereditary antithrombin Ill-deficiency in patients with a history of venous thromboembolism. Thromb. Haemostas.. 1985 in press
    PubMedSuche in Google Scholar
  • 44 Griffin J. H, Mosher D. F, Zimmermann T. S, Kleiss A. J. Protein C, an antithrombotic protein, is reduced in hospitalized patients with intravascular coagulation. Blood 60: 261-264 1982;
    PubMedSuche in Google Scholar
  • 45 Vigano S, Manucci P. M, Solinas S, Bottasso B, Mariani G. Decrease in protein C antigen and formation of an abnormal protein soon after starting oral anticoagulant treatment. Brit. J. Haemat 57: 213-220 1984;
    CrossrefPubMedSuche in Google Scholar
  • 46 Pabinger-Fasching I, Lechner K. Protein- C-Mangel und Thromboseneigung. Fol. Haematol. Ill 04: 416-420 1984;
    PubMedSuche in Google Scholar
  • 47 Loeliger E. A, Broekmanns A. W. Drugs affecting blood clotting, fibrinolysis, and hemostasis. In: Meyler’s side effect of drugs, 659 1984
    PubMedSuche in Google Scholar
  • 48 Loeliger E. A, Broekmanns A. W. Drugs affecting blood clotting, fibrinolysis, and hemostasis. In: Meyler’s side effect of drugs 659 1984;
    PubMedSuche in Google Scholar
  • 49 Mannucci P. M, Viagno S. Protein C concentrates for therapeutic use. Lancet / 875 1983;
    PubMedSuche in Google Scholar
  • 50 McGehee W. G, Klotz T. A, Epstein D. J, Rapaport S. I. Coumarin necrosis associated with hereditary protein C deficiency. Ann. Int. Med 100: 59-60 1984;
    CrossrefPubMedSuche in Google Scholar
  • 51 Mannucci P. M, Viagno S. Protein C concentrates for therapeutic use. Lancet / 875 1983;
    PubMedSuche in Google Scholar
  • 52 Katz H. E. JBranson, Marble R, Griffin J. H. Inherited protein C deficiency and coumarin-rèsponsive chronic relapsing purpura fulminans in a newborn infant. Lancet II: 1165-1168 1983;
    PubMedSuche in Google Scholar
  • 53 Mannucci P. M, Viagno S. Protein C concentrates for therapeutic use. Lancet / 875 1983;
    PubMedSuche in Google Scholar
  • 54 Bertina R. M, Broekmanns A. W. Protein C concentrates for therapeutic use. Lancet II: 1384 1982;
    PubMedSuche in Google Scholar
  • 55 Mannucci P. M, Viagno S. Protein C concentrates for therapeutic use. Lancet / 875 1983;
    PubMedSuche in Google Scholar
  • 56 Barbui T, Finazzi G, Vigano S, Mannucci P. M. L-Asparaginase lowers protein C antigen. Thromb. Haemost 52: 216 1984;
    Thieme ConnectPubMedSuche in Google Scholar
  • 57 Barbui T, Rodeghiero F, Meli S, Dini E. Fatal pulmonary embolism and antithrombin III deficiency in adult lymphoblastic leukemia during L-Asparaginase therapy. Acta Haematol 69: 188-191 1983;
    CrossrefPubMedSuche in Google Scholar
  • 58 Thaler E, Baizar E, Kopsa H, Pinggera W. E. Acquired antithrombin III deficiency in patients with glomerular proteinuria. Hemostasis 07: 257-272 1978;
    PubMedSuche in Google Scholar
  • 59 Pabinger-Fasching I, Lechner K, Niessner H, Schmidt P, Balzar E, Mannhalter C. High levels of plasma protein C in nephrotic syndrome. Thromb. Haemostas 53: 5-7 1985;
    PubMedSuche in Google Scholar