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Hamostaseologie 1985; 05(04): 139-143
DOI: 10.1055/s-0038-1655116
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Schattauer GmbH

Protein S und venöse Thrombophilie

H. P. Schwarz
1   Scripps Clinic and Research Foundation, Department of Immunology, La Jolla, California, USA
,
B. Lämmle
1   Scripps Clinic and Research Foundation, Department of Immunology, La Jolla, California, USA
,
J. H. Griffin
1   Scripps Clinic and Research Foundation, Department of Immunology, La Jolla, California, USA
› Author Affiliations
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Publication History

Publication Date:
22 June 2018 (online)

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  • LITERATUR

  • 1 Lämmle B, Griffin J. H. Formation of the fibrin clot: The balance of procoagulant and inhibitory factors. Clinics in Haematology 14: 281-342 1985;
    PubMedSearch in Google Scholar
  • 2 Gardiner J. E, Griffin J. H. Human protein C and thromboembolic disease. Progress in Hematology 23: 265-278 1983;
    PubMedSearch in Google Scholar
  • 3 Esmon C. T. Protein C. Progress in He- mostasis and Thrombosis 07: 25-54 1984;
    PubMedSearch in Google Scholar
  • 4 DiScipio R. G, Hermodson M. A, Yates S. G, Davie E. W. A comparison of human prothrombin, Factor IX (Christmas Factor), Factor X (Stuart Factor) and protein S. Biochemistry 16: 698-706 1977;
    CrossrefPubMedSearch in Google Scholar
  • 5 Nelsestuen G. I, Kisiel W, DiScipio R. G. Interaction of vitamin K-dependent proteins with membranes. Biochemistry 17: 2134-2138 1978;
    CrossrefPubMedSearch in Google Scholar
  • 6 Walker F. J. The regulation of activated protein C by a new protein: A possible function for bovine protein S.J. Biol. Chem. 255: 5521-5524 1980;
    PubMedSearch in Google Scholar
  • 7 Walker F. J. Regulation of activated protein C by protein S: The role of phospholipid in Factor Va inactivation. J. Biol. Chem. 256: 11128-11131 1981;
    PubMedSearch in Google Scholar
  • 8 Gardiner J. E, McGann M. A, Berridge C. W, Fulcher C, Zimmerman T, Griffin J. H. Protein S as a cofactor for activated protein C in plasma and in the inactivation of purified Factor VIII :C. Circulation. 70: 820 (Abstr.) 1984;
    PubMedSearch in Google Scholar
  • 9 Griffin J. H, Evatt B, Zimmerman T. S, Kleiss A. J, Wideman C. Deficiency of protein C in congenital thrombotic disease. J. Clin. Invest 68: 1370-1373 1981;
    CrossrefPubMedSearch in Google Scholar
  • 10 Bertina R. M, Broekmans A. W, van der Linden I. K, Mertens K. Protein C deficiency in a Dutch family with thrombotic disease. Thromb. Haemost 48: 1-5 1982;
    PubMedSearch in Google Scholar
  • 11 Broekmans A. W, Veitkamp J. J, Bertina R. Congenital protein C deficiency and venous thromboembolism. N. Engl. J. Med. 309: 340-344 1983;
    CrossrefPubMedSearch in Google Scholar
  • 12 Pabinger-Fasching I, Bertina R. M, Lechner K, Niessner H, Korninger C. H. Protein C deficiency in two Austrian families. Thromb. Haemost. 50: 810-813 1983;
    Thieme ConnectPubMedSearch in Google Scholar
  • 13 Schwarz H. P, Fischer M, Hopmeier P, Batard M. A, Griffin J. H. Plasma protein S deficiency in familial thrombotic disease. Blood 64: 1297-1300 1984;
    PubMedSearch in Google Scholar
  • 14 Comp P. C, Nixon R. R, Cooper M. R, Esmon C. T. Familial protein S deficiency is associated with recurrent thrombosis. J. Clin. Invest 74: 2082-2088 1984;
    CrossrefPubMedSearch in Google Scholar
  • 15 Comp P. C, Esmon C. T. Recurrent venous thromboembolism in patients with partial deficiency of protein S.N. Engl. J. Med. 311: 1525-1528 1984;
    CrossrefPubMedSearch in Google Scholar
  • 16 Broekmans A. W, Bertina R. M, Reinalda-Poot J, Engesser L, Muller H. P, Leeuw J. A, Michiels J. J, Brommer E. J. P, Briët E. Hereditary protein S deficiency and venous thrombo-embolism. A study in three Dutch families. Thromb. Haemost 53: 273-277 1985;
    PubMedSearch in Google Scholar
  • 17 Dahlbäck B. Purification of human vitamin K-dependent protein S and its limited proteolysis by thrombin. Biochem. J. 209: 837-846 1983;
    CrossrefPubMedSearch in Google Scholar
  • 18 DiScipio R. G, Davie E. W. Characterization of protein S, a y-carboxy-glutamic acid containing protein from bovine and human plasma. Biochemistry 18: 899-904 1979;
    CrossrefPubMedSearch in Google Scholar
  • 19 Esmon C. T, Sadowski J. A, Suttie J. W. A new carboxylation reaction. The vitamin K-dependent incorporation of H14CO3 into prothrombin. J. Biol. Chem. 250: 4744-4748 1975;
    PubMedSearch in Google Scholar
  • 20 Lindhout M. J, Kop-Klaassen B. H. M, Hemker H. C. The effect of gammacarbo- xyglutamate residues on the enzymatic properties of the activated blood clotting Factor Xa. Biochim. Biophys. Acta. 533: 342-354 1978;
    CrossrefPubMedSearch in Google Scholar
  • 21 Fernlund P, Stenflo J. ß-hydroxyaspartic acid in vitamin K-dependent proteins. J. Biol. Chem. 258: 12509-12512 1983;
    PubMedSearch in Google Scholar
  • 22 Stenflo J, Jönsson M. Protein S, a new vitamin K-dependent protein from bovine plasma. FEBS-Letter 101: 377-381 1979;
    PubMedSearch in Google Scholar
  • 23 Walker F. J. Protein S and the regulation of activated protein C. Semin. Thromb. Hemost. 10: 131-138 1984;
    Thieme ConnectPubMedSearch in Google Scholar
  • 24 Stenflo J. Structure and function of protein C. Semin. Thromb. Hemost. 10: 109-121 1984;
    Thieme ConnectPubMedSearch in Google Scholar
  • 25 Suzuki K, Nishioka J, Hashimoto S. Regulation of activated protein C by thrombin modified protein S.J. Biochem. 94: 699-705 1983;
    CrossrefPubMedSearch in Google Scholar
  • 26 Walker F. J. Regulation of vitamin K-dependent protein S. Inactivation by thrombin. J. Biol. Chem. 259: 10335-10339 1984;
    PubMedSearch in Google Scholar
  • 27 Dahlbäck B. Interaction between vitamin K-dependent protein S and the complement protein, C4b-binding protein. Semin. Thromb. Hemost. 10: 139-148 1984;
    Thieme ConnectPubMedSearch in Google Scholar
  • 28 Miletich J. P, Jackson C. M, Majerus P. W. Interaction of coagulation Factor Xa with human platelets. Proc. Natl. Acad. Sci. USA. 74: 4033-4036 1977;
    CrossrefPubMedSearch in Google Scholar
  • 29 Tracy P. B, Nesheim M. E, Mann K. G. Coordinate binding of Factor Va and Factor Xa to the unstimulated platelet. J. Biol. Chem. 256: 743-751 1981;
    PubMedSearch in Google Scholar
  • 30 Guinto E. R, Esmon C. T. Loss of prothrombin and of Factor Xa-Factor Va interactions upon inactivating of Factor Va by activated protein C.J. Biol. Chem. 259: 13986-13992 1984;
    PubMedSearch in Google Scholar
  • 31 Comp P. C, Esmon C. T. Activated protein C inhibits prothrombin converting activity. Blood 54: 1272-1281 1979;
    PubMedSearch in Google Scholar
  • 32 Dahlbäck B, Stenflo J. Inhibitory effect of activated protein C on activation of prothrombin by platelet bound Factor Xa. Eur. J. Biochem. 107: 331-335 1980;
    PubMedSearch in Google Scholar
  • 33 Harris K. W, Esmon C. T. Protein S is required for bovine platelets to support activated protein C binding and activity. J. Biol. Chem. 260: 2007-2010 1985;
    PubMedSearch in Google Scholar
  • 34 Schwarz H. P, Heeb M. J, Wencel-Drake J, Griffin J. H. Identification and quantitation of protein S in human platelets. Blood. 1985 (in press).
    PubMedSearch in Google Scholar
  • 35 Fair D. S, Revak D. J. Quantitation of human protein S in the plasma of normal and warfarin treated individuals by radioimmunoassay. Thromb. Res. 36: 527-535 1984;
    CrossrefPubMedSearch in Google Scholar
  • 36 Bertina R. M, van Wijngaarden A, Reinalda-Poot J, Poort S. R, Bom V. J. J. Determination of plasma protein S - The protein cofactor of activated protein C. Thromb. Haemost 53: 268-272 1985;
    Thieme ConnectPubMedSearch in Google Scholar
  • 37 Szatkowski N. S, Miller C. M, Endres-Brooks J. L, Madden M, Marlar R. A. Clinical studies of human protein S and identification of a patient with protein S deficiency and thrombotic complications. Circulation 70: 813 (Abstr.) 1984;
    PubMedSearch in Google Scholar
  • 38 Aoki N, Moroi M, Sakata Y, Yoshi-da N, Matsuda M. Abnormal plasminogen. A hereditary molecular abnormality found in a patient with recurrent thrombosis. J. Clin. Invest 61: 1186-1195 1978;
    PubMedSearch in Google Scholar
  • 39 Thaler E, Lechner K. Antithrombin III deficiency and thromboembolism. Clinics in Hematology 10: 369-390 1981;
    PubMedSearch in Google Scholar
  • 40 Beck E. A, Charache P, Jackson D. P. A new inherited coagulation disorder caused by an abnormal fibrinogen (»Fibrinogen Baltimore«). Nature 208: 143-145 1965;
    CrossrefPubMedSearch in Google Scholar
  • 41 Schwarz H. P, Griffin J. H. Mechanism of action of Protein C. In: Witt I. CProtein. (Ed.). de Gruyter. Berlin: 1985 (in press).
    PubMedSearch in Google Scholar