Acquired Factor X Deficiency in a Patient with Amyloidosis

Kristoffer Korsan-Bengtsen; Peter F Hjort; Johan Ygge

doi:10.1055/s-0038-1655405

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1962; 07(03): 558-566
DOI: 10.1055/s-0038-1655405

Originalarbeiten — Original Articles — Travaux Originaux

Schattauer GmbH

Acquired Factor X Deficiency in a Patient with Amyloidosis

Kristoffer Korsan-Bengtsen

¹Medical Department II, Sahlgrenska Hospital, University of Göteborg, Sweden, and Institute for Thrombosis Research, University Hospital, Rikshospitalet, Oslo, Norway

,

Peter F Hjort

¹Medical Department II, Sahlgrenska Hospital, University of Göteborg, Sweden, and Institute for Thrombosis Research, University Hospital, Rikshospitalet, Oslo, Norway

,

Johan Ygge

¹Medical Department II, Sahlgrenska Hospital, University of Göteborg, Sweden, and Institute for Thrombosis Research, University Hospital, Rikshospitalet, Oslo, Norway

› Author Affiliations

Abstract

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Summary

A patient with extensive amyloidosis and a selective factor X deficiency is described. The following observations indicate that the factor X deficiency in this case is not inherited.

1. The first symptoms of a bleeding tendency appeared at an age of 50 years.

2. The patient’s four children had no clotting defect.

3. After infusion of 1 liter of fresh plasma no increased factor X activity was observed. No anticoagulants could be demonstrated in vitro.

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References

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