Thromb Haemost 1962; 08(02): 311-314
DOI: 10.1055/s-0038-1655430
Originalarbeiten – Original Articles – Travaux Originaux
Schattauer GmbH

Effect of Lecithin on the Fibrinolytic System in Guinea-Pig Serum

E. S Olesen
1   Biological Institute of the Carlsberg Foundation, Copenhagen, Denmark
› Author Affiliations
Further Information

Publication History

Publication Date:
14 May 2019 (online)

Summary

Lecithin preparations from egg yolk or from soya beans added to guinea-pig serum which is subjected to isoelectric precipitation produce fibrinolytic activity in the precipitates in a manner similar to that previously reported for anionic polyelectrolytes. The possible physiological significance of this observation is discussed.

 
  • References

  • 1 Astrup T, Müllertz S. The fibrin plate method for estimating fibrinolytic activity.. Arch. Biochem. 40: 346-351. 1952;
  • 2 Bungenberg de Jong. in Colloidal Science II.. Kruyt H. R. (Ed.) Elsevier; Amsterdam: 1949: 295
  • 3 Bungenberg de Jong, Westerkamp R. F. Zur Kenntnis der Komplexkoazervation. VI. Mitteilung: Lecithin als Komplexteilnehmer.. Biochem. Z. 234: 367-400. 1931;
  • 4 Halse Th. Fibrinolyse. Eine experimentelle und klinische Studie über die 4. Phase der Blutgerinnung.. Cantor; Freiburg: 1948
  • 5 v. Kaulla K. N. Gibt es Wege zur therapeutischen Verwertung der Fibrinolyse? Wien.. Z. inn. Med. 33: 329-344. 1952;
  • 6 Lassen M. Heat denaturation of plasminogen in the fibrin plate method.. Acta physiol. scand. 27: 371-376. 1952;
  • 7 Olesen E. S. Effect of acid polysaccharides on the fibrinolytic system in guinea-pig serum.. Acta pharmacol. 1959; a 15: 307-318.
  • 8 Olesen E. S. Effect of anionic polyelectrolytes on the fibrinolytic system of guinea-pig serum.. Acta pharmacol. 1959; b 16: 38-45.
  • 9 Olesen E. S. Activation of fibrinolysis in guinea-pig serum by bile acids.. Thrombos. Diathes. haemorrh. 1960; a 4: 473-481.
  • 10 Olesen E. S. Fibrinolytic activity induced in guinea-pig serum by protamine and quarter-nary ammonium bases.. Acta pharmacol. 1960; b 17: 191-199.
  • 11 Olesen E. S. A fibrinolytic system in human plasma activated by peptone or acid polysaccharides.. Scand. J. clin. Lab. Invest. 1961; 13: 410-415.