Fibrinolytic Activity in Man During Surgery

Lennart Andersson; Inga Marie Nilsson; Bertil Olow

doi:10.1055/s-0038-1655482

Thrombosis and Haemostasis, Inhaltsverzeichnis

Thromb Haemost 1962; 07(03): 391-403
DOI: 10.1055/s-0038-1655482

Originalarbeiten — Original Articles — Travaux Originaux

Schattauer GmbH

Fibrinolytic Activity in Man During Surgery^[*]

Lennart Andersson

¹Urologic Unit of the Department of Surgery, University of Lund, Lunds Lasarett, Lund; Department of Medicine, University of Lund, Allmänna Sjukhuset, Malmö; Department of Surgery, University of Lund, Allmänna Sjukhuset, Malmö, Sweden

,

Inga Marie Nilsson

¹Urologic Unit of the Department of Surgery, University of Lund, Lunds Lasarett, Lund; Department of Medicine, University of Lund, Allmänna Sjukhuset, Malmö; Department of Surgery, University of Lund, Allmänna Sjukhuset, Malmö, Sweden

,

Bertil Olow

¹Urologic Unit of the Department of Surgery, University of Lund, Lunds Lasarett, Lund; Department of Medicine, University of Lund, Allmänna Sjukhuset, Malmö; Department of Surgery, University of Lund, Allmänna Sjukhuset, Malmö, Sweden

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Abstract

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Summary

165 patients undergoing various operations were studied for any variation in the fibrinolytic activity of the blood, as measured by a modified fibrin plate method.

The fibrinolytic activity was found to increase somewhat already after induction of anaesthesia, and almost always slightly to moderately during the actual operation.

This activity is believed to be due to an increase of the plasminogen activator in the blood, since it can be inhibited by administration of ε-aminocaproic acid. It is presumably a normal reaction and, unless extreme or combined with some coagulation disorder, it probably has but little influence on blood loss at operation.

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Referenzen

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Fibrinolytic Activity in Man During Surgery[*]

Fibrinolytic Activity in Man During Surgery^[*]