Metastasis from Intracranial Mesenchymal Chondrosarcoma: Report of a Rare Case

Abstract

Chondrosarcoma is a rare malignant tumor originating from cartilaginous tissue with a tendency to localize in the epiphysis of long and pelvic bones. Only 7% of all chondrosarcomas originate in the craniocervical region. Metastasis from intracranial chondrosarcoma is extremely rare with only two previously reported cases. We report on a young patient with intracranial chondrosarcoma who presented with extracranial metastasis 2 years after surgical excision of the primary lesion. Gross total excision combined with radiotherapy so far has led to a favorable outcome.

Keywords

chondrosarcoma - intracranial - metastasis - extracranial

• References

• 1 Oruckaptan HH, Berker M, Soylemezoglu F, Ozcan OE. Parafalcine chondrosarcoma: an unusual localization for a classical variant. Case report and review of the literature. Surg Neurol 2001; 55 (03) 174-179
• 2 Waga S, Matsushima M, Ando K, Morii S. Intracranial chondrosarcoma with extracranial metastases. Case report. J Neurosurg 1972; 36 (06) 790-794
• 3 el-Gindi S, Abd-el-Hafeez M, Salama M. Extracranial skeletal metastases from an intracranial meningeal chondrosarcoma. Case report. J Neurosurg 1974; 40 (05) 651-653
• 4 Berkmen YM, Blatt ES. Cranial and intracranial cartilaginous tumours. Clin Radiol 1968; 19 (03) 327-333
• 5 Chandler JP, Yashar P, Laskin WB, Russell EJ. Intracranial chondrosarcoma: a case report and review of the literature. J Neurooncol 2004; 68 (01) 33-39
• 6 Salcman M, Scholtz H, Kristt D, Numaguchi Y. Extraskeletal myxoid chondrosarcoma of the falx. Neurosurgery 1992; 31 (02) 344-348
• 7 Parker JR, Zarabi MC, Parker Jr JC. Intracerebral mesenchymal chondrosarcoma. Ann Clin Lab Sci 1989; 19 (06) 401-407
• 8 Alvira MM, McLaurin RL. Asymptomatic subdural chondrosarcoma. Case report. J Neurosurg 1978; 48 (05) 825-828
• 9 Steiner GC, Mirra JM, Bullough PG. Mesenchymal chondrosarcoma. A study of the ultrastructure. Cancer 1973; 32 (04) 926-939
• 10 Glasauer FE, Yuan RH. Intracranial tumors with extracranial metastases. Case report and review of the literature. J Neurosurg 1963; 20: 474-493
• 11 Dowling EA. Mesenchymal chondrosarcoma. J Bone Joint Surg Am 1964; 46: 747-754
• 12 La Spina M, Dollo C, Giangaspero F, Bertolini P, Russo G. Intracranial mesenchymal chondrosarcoma with osteoid formation: report of a pediatric case. Childs Nerv Syst 2003; 19 (09) 680-682