Normal Prevalence of Factor V Leiden Gene Mutation in Patients with Severe Unstable Angina

P W H M Verheggen; B T Heymans; P E Slagboom; F Haverkate; V Manger Cats

doi:10.1055/s-0038-1656142

Thrombosis and Haemostasis, Inhaltsverzeichnis

Thromb Haemost 1997; 77(06): 1218
DOI: 10.1055/s-0038-1656142

Letters to the Editor

Schattauer GmbH Stuttgart

Normal Prevalence of Factor V Leiden Gene Mutation in Patients with Severe Unstable Angina

P W H M Verheggen

¹The Department of Cardiology, Leiden University Hospital, Leiden, The Netherlands

,

B T Heymans

²Gaubius Laboratory, TNO-PG, Leiden, The Netherlands

,

P E Slagboom

²Gaubius Laboratory, TNO-PG, Leiden, The Netherlands

,

F Haverkate

²Gaubius Laboratory, TNO-PG, Leiden, The Netherlands

,

V Manger Cats

¹The Department of Cardiology, Leiden University Hospital, Leiden, The Netherlands

› Institutsangaben

Abstract

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Referenzen

References
1 Bertina RM, Koeleman PBC, Koster T, Rosendaal FR, Dirven RJ, de Ronde H, van der Velden PA, Reitsma PH. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 1994; 369: 64-67
2 Dahlbäck B. Inherited thrombophilia: resistance to activated protein C as a pathogenic factor of venous thromboembolism. Blood 1995; 85: 607-614
3 Fuster V, Badimon L, Badimon JJ, Chesebro JH. The pathogenesis of coronary artery disease and the acute coronary syndromes: Part 1 and 2. N Engl J Med 1992; 326 242-250 301-308
4 Chesebro JH, Fuster V. Thrombosis in unstable angina. N Engl J Med 1992; 327: 192-194
5 Braunwald E, Jones RH, Marks DB. et al Diagnosing and managing unstable angina. Circulation 1994; 90: 613-622
6 Ardissino D, Gamba MG, Merlini PA, Rolla A, Barberis P, Demicheli G, Testa S, Bruno N, Specchia G. Fibrinopeptide A excretion in urine: a marker of the cumulative thrombin activity in stable versus unstable angina patients. Am J Cardiol 1991; 68: 58-63B
7 Merlini PA, Bauer KA, Oltrona L, Ardissino D, Cattaneo M, Belli C, Mannucci PM, Rosenberg R. Persistent activation of coagulation mechanism in unstable angina and myocardial infarction. Circulation 1994; 90: 61-68
8 Becker RC, Cannon CP, Bovill EG, Tracy RP, Thompson B, Knatterud GL, Randall A, Braunwald E. for the TIMI III Investigators. Prognostic value of plasma fibrinogen concentration in patients with unstable angina and non-Q-wave myocardial infarction. Am J Cardiol 1996; 78: 142-147
9 Ardissino D, Merlini PA, Gamba G, Barberis P, Demicheli G, Tests A, Colombi E, Poli A, Fetiveau R, Montemartini C. Thrombin activity an early outcome in unstable angina pectoris. Circulation 1996; 93: 1634-1639
10 Rosendaal FR, Koster T, Vandenbroucke JP, Reitsma PH. High risk of thrombosis in patients homozygous for factor V Leiden (activated protein C resistance). Blood 1995; 85: 1504-1508
11 Ridker PM, Hennekens CH, Lindpaintner K, Stampfer M, Eisenberg P, Miletich J. Mutation in the gene coding for coagulation factor V and the risk of myocardial infarction, stroke and venous thrombosis in apparently healthy men. N Engl J Med 1995; 332: 912-917
12 Prohaska W, Mannebach H, Schmidt M, Gleichmann U, Kleesiek K. Evidence against heterozygous coagulation factor V 1691 G-A mutation with resistance to activated protein C being a risk factor for coronary artery disese and myocardial infarction. J Mol Med 1995; 73 (10) 521-524
13 Ardissino D, Peyvandi F, Merlini PA, Colombi E, Mannucci PM. Factor V (Arg506-Gln) mutation in young survivors of myocardial infarction. Thromb Haemost 1996; 75: 701-702