The Biological Half-Time of Hageman Factor

J. J Veltkamp; E. A Loeliger; H. C Hemker

doi:10.1055/s-0038-1656281

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1965; 13(01): 001-007
DOI: 10.1055/s-0038-1656281

Originalarbeiten — Original Articles — Travaux Originaux

Schattauer GmbH

The Biological Half-Time of Hageman Factor

J. J Veltkamp

¹Haematology Section of the Department of Internal Medicine, (Head: Prof. J. Mulder, M. D.), University Hospital, Leyden, The Netherlands

,

E. A Loeliger

¹Haematology Section of the Department of Internal Medicine, (Head: Prof. J. Mulder, M. D.), University Hospital, Leyden, The Netherlands

,

H. C Hemker

¹Haematology Section of the Department of Internal Medicine, (Head: Prof. J. Mulder, M. D.), University Hospital, Leyden, The Netherlands

› Author Affiliations

Abstract

Summary

The biological half-time of factor XII was assessed (a) after transfusion of freshly-drawn, normal intact ACD-plasma into a patient having Hageman trait and suffering from polycythaemia vera, and (b) with blocked synthesis in a patient suffering from acute liver dystrophy due to phosphoric intoxication. The results obtained suggest that the biological half-time under normal conditions has a value between 50 and 70 hrs.

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References

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