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J Pediatr Intensive Care 2018; 07(04): 188-195
DOI: 10.1055/s-0038-1656535
Original Article
Georg Thieme Verlag KG Stuttgart · New York

Presence of Invasive Devices and Risks of Healthcare-Associated Infections and Sepsis

Erin E. Bennett
1   Division of Critical Care, Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States
,
John VanBuren
1   Division of Critical Care, Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States
,
Richard Holubkov
1   Division of Critical Care, Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States
,
Susan L. Bratton
1   Division of Critical Care, Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States
› Institutsangaben Funding The University of Utah supported the project with salary support for employee effort for statistical analysis.
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Publikationsverlauf

06. März 2018

24. April 2018

Publikationsdatum:
23. Mai 2018 (online)

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Abstract

The present study evaluated the daily risk of healthcare-associated infections and sepsis (HAIS) events in pediatric intensive care unit patients with invasive devices. This was a retrospective cohort study. Invasive devices were associated with significant daily risk of HAIS (p < 0.05). Endotracheal tubes posed the greatest risk of HAIS (hazard ratio [HR]: 4.39, confidence interval [CI]: 2.59–7.46). Children with both a central venous catheter (CVC) and urinary catheter (UC) had over 2.5-fold increased daily risk (HR: 2.59, CI: 1.18–5.68), in addition to daily CVC risk (HR: 3.06, CI: 1.38–6.77) and daily UC risk (HR: 8.9, CI: 3.62–21.91). We conclude that a multistate hazard model optimally predicts daily HAIS risk.

Keywords

healthcare-associated infection - sepsis - catheter-associated infections
 

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