Synthesis of Thromboplastin Protein by a Murine Macrophage-Like Cell Line

T Lyberg; Ø Hetland; H Prydz

doi:10.1055/s-0038-1657152

Thrombosis and Haemostasis, Inhaltsverzeichnis

Thromb Haemost 1982; 47(02): 154-156
DOI: 10.1055/s-0038-1657152

Original Article

Schattauer GmbH Stuttgart

Synthesis of Thromboplastin Protein by a Murine Macrophage-Like Cell Line

T Lyberg

The Research Institute for Internal Medicine, University of Oslo, Rikshospitalet, Oslo, Norway

,

Ø Hetland

The Research Institute for Internal Medicine, University of Oslo, Rikshospitalet, Oslo, Norway

,

H Prydz

The Research Institute for Internal Medicine, University of Oslo, Rikshospitalet, Oslo, Norway

› Institutsangaben

Abstract

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Summary

The established murine macrophage cell line J-774.1 responds to endotoxin with synthesis of thromboplastin apoprotein. The response develops in the absence of added lymphocytes and there is no increased responsiveness in cocultures of J-774.1 cells and BALB/c lymphocytes. J-774.1 cells therefore do not depend on lymphocyte cooperation for their response to endotoxin.

Key words

Endotoxin - J-774.1 cells - Lymphocytes - Thromboplastin - TPA

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Referenzen

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