Thromb Haemost 1982; 47(02): 154-156
DOI: 10.1055/s-0038-1657152
Original Article
Schattauer GmbH Stuttgart

Synthesis of Thromboplastin Protein by a Murine Macrophage-Like Cell Line

T Lyberg
The Research Institute for Internal Medicine, University of Oslo, Rikshospitalet, Oslo, Norway
,
Ø Hetland
The Research Institute for Internal Medicine, University of Oslo, Rikshospitalet, Oslo, Norway
,
H Prydz
The Research Institute for Internal Medicine, University of Oslo, Rikshospitalet, Oslo, Norway
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Received 17. November 1981

Accepted 01. März 1982

Publikationsdatum:
13. Juli 2018 (online)

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Summary

The established murine macrophage cell line J-774.1 responds to endotoxin with synthesis of thromboplastin apoprotein. The response develops in the absence of added lymphocytes and there is no increased responsiveness in cocultures of J-774.1 cells and BALB/c lymphocytes. J-774.1 cells therefore do not depend on lymphocyte cooperation for their response to endotoxin.