Lipoprotein Fractions and Antithrombin III Consumption During Clotting

J H Winter; B Bennett; F McTaggart; A S Douglas

doi:10.1055/s-0038-1657176

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1982; 47(03): 236-238
DOI: 10.1055/s-0038-1657176

Original Article

Schattauer GmbH Stuttgart

Lipoprotein Fractions and Antithrombin III Consumption During Clotting

J H Winter

The Department of Medicine, University of Aberdeen, Scotland, U.K.

,

B Bennett

The Department of Medicine, University of Aberdeen, Scotland, U.K.

,

F McTaggart

^*The Imperial Chemical Industries Limited, Pharmaceuticals Division Alderley Park, Cheshire, U.K.

,

A S Douglas

The Department of Medicine, University of Aberdeen, Scotland, U.K.

› Author Affiliations

Abstract

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Summary

Plasma and serum antithrombin levels were measured in functional (initial rate measurement) and immunological assays together with serum lipid levels in normal subjects and patients with coronary artery disease. Specific antithrombin activity in plasma showed a negative correlation with triglyceride levels. The consumption of antithrombin activity during blood clotting was negatively correlated with both serum total triglyceride and heparin precipitable lipoprotein and positively correlated with serum high density lipoprotein cholesterol. Different blood lipoprotein fractions may influence the activity of the antithrombin III molecule.

Key words

Keywords Antithrombin III - Lipoproteins

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References

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