Thromb Haemost 1982; 47(03): 236-238
DOI: 10.1055/s-0038-1657176
Original Article
Schattauer GmbH Stuttgart

Lipoprotein Fractions and Antithrombin III Consumption During Clotting

J H Winter
The Department of Medicine, University of Aberdeen, Scotland, U.K.
,
B Bennett
The Department of Medicine, University of Aberdeen, Scotland, U.K.
,
F McTaggart
*   The Imperial Chemical Industries Limited, Pharmaceuticals Division Alderley Park, Cheshire, U.K.
,
A S Douglas
The Department of Medicine, University of Aberdeen, Scotland, U.K.
› Author Affiliations
Further Information

Publication History

Received 07 December 1981

Accepted 29 March 1982

Publication Date:
13 July 2018 (online)

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Summary

Plasma and serum antithrombin levels were measured in functional (initial rate measurement) and immunological assays together with serum lipid levels in normal subjects and patients with coronary artery disease. Specific antithrombin activity in plasma showed a negative correlation with triglyceride levels. The consumption of antithrombin activity during blood clotting was negatively correlated with both serum total triglyceride and heparin precipitable lipoprotein and positively correlated with serum high density lipoprotein cholesterol. Different blood lipoprotein fractions may influence the activity of the antithrombin III molecule.