Higher Fibrin-Binding and Thrombolytic Properties of Single Polypeptide Chain - High Molecular Weight Urokinase

Thromb Haemost 1982; 47(03): 297
DOI: 10.1055/s-0038-1657192

Letter to the Editor

Schattauer GmbH Stuttgart

H Sumi

¹Department of Physiology, Miyazaki Medical College, Myazaki, 889-16, Japan

,

M Maruyama

¹Department of Physiology, Miyazaki Medical College, Myazaki, 889-16, Japan

,

O Matsuo

¹Department of Physiology, Miyazaki Medical College, Myazaki, 889-16, Japan

,

H Mihara

¹Department of Physiology, Miyazaki Medical College, Myazaki, 889-16, Japan

,

N Toki

²Department of Dermatology, Hiroshima University School of Medicine, Hiroshima 734, Japan

References
1 Sumi H, Robbins KC. The preparation and characterization of a functionally-active urokinase heavy chain prepared from high molecular weight urokinase. In: Progress in Fibrinolysis. Davidson JF, Nilsson IM, Astedt B. (Eds). Churchill Livingstone; Edinburgh: 1981: 36-37
2 Sumi H, Kosugi T, Matsuo O, Mihara H. Some properties of a high molecular form kidney tissue cultured urokinase. Abstract of 3th Congress of Japanese Society on Thrombosis and Haemostasis, Tokyo. 1980: 91
3 Sumi H, Kosugi T, Matsuo O, Mihara H. Physicochemical properties of highly purified kidney cultured plasminogen activator (single chain-urokinase). Acta Haematol Jpn. 1982 45 (No. 1: in press
4 Husain SS, Gurewich V, Lipinski B. Purification of new high MW single chain form of urokinase (UK) from urine. Thromb Haemostas 1981; 46: 11 (Abstr.).
5 Sasaki K, Hatsuoka M, Toki N, Sumi H. Fibrinolytic and coagulation activity level during formation of experimental thrombus in dog’s saphena vein. Life Sci 1980; 27: 1659-1667