Download PDF
Thromb Haemost 1983; 49(03): 187-189
DOI: 10.1055/s-0038-1657358
Original Article
Schattauer GmbH Stuttgart

Hemarthroses and Warfarin: Joint Destruction with Anticoagulation

W Abe Andes
The Departments of Medicine and Orthopaedics, Tulane University School of Medicine, The Veterans Administration Hospital of New Orleans and The Louisiana Comprehensive Hemophilia Care Center, New Orleans, Louisiana, U.S.A.
,
J Ollie Edmunds
The Departments of Medicine and Orthopaedics, Tulane University School of Medicine, The Veterans Administration Hospital of New Orleans and The Louisiana Comprehensive Hemophilia Care Center, New Orleans, Louisiana, U.S.A.
› Author Affiliations
Further Information

Publication History

Received 19 January 1983

Accepted 23 March 1983

Publication Date:
18 July 2018 (online)

Also available at
  PDF Download  Permissions and Reprints

Summary

A 56 year old man was seen because of recurrent right shoulder hemarthroses and a superior vena caval syndrome. Intermittent symptoms had occurred for six years and resulted in marked destructive changes in the right shoulder. Arthroscopy added pathological evidence of this unusual mechanism of arthropathy. Patients on anticoagulants deserve close attention to symptoms of occult bleeding.

Keywords

Warfarin - Hemarthroses - Anticoagulation - Arthropathy
 

  • References

  • 1 Houghton GR, Duthie RB. Orthopedic problems in hemophilia. Clin Orthop 1979; 138: 197-216
    PubMedGoogle Scholar
  • 2 Hasselbacher P, Schimmer BM, Weinberger A. Hemarthroses with sodium warfarin and heparin. Arthritis Rheum 1978; 21: 740
    PubMedGoogle Scholar
  • 3 Jaffer AM, Schmid FR. Hemarthroses associated with sodium warfarin. J Rheumatol 1977; 4: 215-217
    PubMedGoogle Scholar
  • 4 McLauglin GE, McCarty Jr DR, Segal BL. Hemarthrosis complicating anticoagulant therapy. Report of three cases. JAMA 1966; 196: 202-203
    CrossrefPubMedGoogle Scholar
  • 5 Wild JH, Zvaifler NJ. Hemarthrosis associated with sodium warfarin therapy. Arthritis Rheum 1976; 19: 98-102
    CrossrefPubMedGoogle Scholar
  • 6 Katz AL, Alepa FP. Hemarthrosis secondary to heparin therapy. Arthritis Rheum 1976; 19: 966
    PubMedGoogle Scholar
  • 7 Mayer JW. Hemarthrosis in a heparinized patient. Arthritis Rheum 1977; 20: 901
    PubMedGoogle Scholar
  • 8 Hale WB, Moorthy AV, Middleton WS. Hemarthrosis from heparin therapy. JAMA 1980; 244: 30
    PubMedGoogle Scholar
  • 9 Sjamsoedin LJ M, Heijnen L, Mauser-Bunschoten EP, Van GeijlswijkJ L, Van HouwelingenH, Van AstenP, Sixma JJ. The effect of activated prothrombin-complex concentrate (FEIBA) on joint and muscle bleeding in patients with hemophilia A and antibodies to factor Vlll. A double-blind clinical trial. N Engl J Med 1981; 305: 717-721
    CrossrefPubMedGoogle Scholar
  • 10 Lusher JM, Shapiro SS, Palasaak JE, Rao AV, Levine PH, Blatt PM. Efficacy of prothrombin-complex concentrates in hemophiliacs with antibodies for factor VIII. N Engl J Med 1980; 303: 421-425
    CrossrefPubMedGoogle Scholar
  • 11 Biggers JA, Remmers AR, Classford DM, Sarles HE, Lindley JD, Fish JC. The risk of anticoagulation in hemodialysis patients. Nephron 1977; 18: 109-113
    CrossrefPubMedGoogle Scholar
  • 12 Gallop PM, Lian JB, Hauschka PV. Carboxylated calcium-binding proteins and vitamin K. N Engl J med 1980; 302: 1460-1466
    CrossrefPubMedGoogle Scholar