Download PDF
Thromb Haemost 1997; 78(04): 1296
DOI: 10.1055/s-0038-1657732
Letter to the Editor
Schattauer GmbH Stuttgart

Detection of Factor V Leiden Using ASO (Allele Specific Oligonucleotide)

N Hézard
The Laboratoire central d’Hématologie, CHU Robert Debré, Reims, France
,
P Cornillet
The Laboratoire central d’Hématologie, CHU Robert Debré, Reims, France
,
A Vallade
The Laboratoire central d’Hématologie, CHU Robert Debré, Reims, France
,
P Nguyen
The Laboratoire central d’Hématologie, CHU Robert Debré, Reims, France
› Author Affiliations
Further Information

Publication History

Received 27 1997

Accepted after resubmisson 20 June 1997

Publication Date:
30 July 2018 (online)

Also available at
  PDF Download  Permissions and Reprints
 

  • References

  • 1 Bertina RM, Koeleman BPC, Koster T, Rosendaal FR, Dirven RJ, de Ronde H, van der VeldenPA, Reitsma PH. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 1994; 369: 64-67
    CrossrefPubMedSearch in Google Scholar
  • 2 Beauchamp NJ, Daly ME, Hampton KK, Cooper PC, Preston FE, Peake IR. Rapid two-stage PCR for detecting factor V G1691A mutation. Lancet 1994; 344: 694-5
    PubMedSearch in Google Scholar
  • 3 Gandrille S, Alhenc-Gelas M, Aiach M. A rapid screening method for factor Arg 506→Gln mutation. Blood Coag Fibrinol 1995; 6: 245-248
    CrossrefPubMedSearch in Google Scholar
  • 4 Rabès JP, Trossaert M, Conard J, Samama M, Giraudet P, Boileau C. Single point mutation at Arg 506 of factor V associated with APC resistance and venous thromboembolism: improved detection by PCR-mediated site-detected mutagenesis. Thromb Haemost 1995; 74: 1379-1380
    Thieme ConnectPubMedSearch in Google Scholar
  • 5 Gandrille S, Goossens M, Aiach M. Scanning method to establish the molecular basis of protein C deficiencies. Hum Mutat 1994; 4: 23-30
    PubMedSearch in Google Scholar
  • 6 Corral J, Iniesta JA, Gonzalez-Connejero R, Vicente V. Detection of factor Leiden from a drop of blood by PCR-SSCP. Thromb Haemost 1996; 76: 735-737
    Thieme ConnectPubMedSearch in Google Scholar
  • 7 Zotz RB, Marhun-Debowski B, Sharf RE. Mutation in the gene coding for coagulation factor V and resistance to activated protein C: detection of the genetic mutation by oligonucleotide ligation assay using a semi-automated system. Thromb Haemost 1996; 76: 53-55
    PubMedSearch in Google Scholar
  • 8 Engel H, Zwang L, van VlietHHDM, Michiels JJ, Stibbe J, Lindemans J. Phenotyping and genotyping of coagulation factor V Leiden. Thromb Haemost 1996; 75: 267-269
    Thieme ConnectPubMedSearch in Google Scholar
  • 9 Van de LochtLTF, Kuypers AWHM, Verbruggen BW, Linssen PCM, Novakova IRO, Mensink EJBM. Semi-automated detection of the factor V mutation by allele specific amplification and capillary electrophoresis. Thromb Haemost 1995; 74: 1276-1279
    Thieme ConnectPubMedSearch in Google Scholar