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Thromb Haemost 1985; 54(02): 475-479
DOI: 10.1055/s-0038-1657877
Original Article
Schattauer GmbH Stuttgart

Epidemiological Study on Factor VII, Factor VIII and Fibrinogen in an Industrial Population: I. Baseline Data on the Relation to Age, Gender, Body-Weight, Smoking, Alcohol, Pill-Using, and Menopause

L Balleisen
The Institute for Arteriosclerosis Research and Department of Internal Medicine, University of Münster, Münster, West Germany
,
J Bailey
The Institute for Arteriosclerosis Research and Department of Internal Medicine, University of Münster, Münster, West Germany
,
P-H Epping
The Institute for Arteriosclerosis Research and Department of Internal Medicine, University of Münster, Münster, West Germany
,
H Schulte
The Institute for Arteriosclerosis Research and Department of Internal Medicine, University of Münster, Münster, West Germany
,
J van de Loo
The Institute for Arteriosclerosis Research and Department of Internal Medicine, University of Münster, Münster, West Germany
› Author Affiliations
Further Information

Publication History

Received 22 January 1985

Accepted 23 May 1985

Publication Date:
18 July 2018 (online)

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Summary

The Münster Arteriosclerosis Study (MAS) is a prospective, longitudinal epidemiological study on an industrial population in Westfalia aimed to establishing clinical and laboratory data with possible relationship to cardiovascular events. The data presented here describe the baseline measurements of fibrinogen, factor VIIc and factor VIIIc from the recruitment of 2880 male and 1306 female persons and their relationship to age, gender, body-weight, smoking, alcohol, pill-using and menopause. The correlations were made by means of a multiple regression analysis. We found an increase of those coagulation factors with age, a correlation of F VII and fibrinogen with body-weight index and of fibrinogen with cigarette smoking. No correlation was found for alcohol consumption. F VIII and F VII were significantly higher after onset of menopause and F VII and fibrinogen in women using the pill.

Keywords

Factor VII - Factor VIII - Fibrinogen - Epidemiology
 

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