CC BY-NC-ND 4.0 · Thorac Cardiovasc Surg Rep 2018; 07(01): e27-e29
DOI: 10.1055/s-0038-1660806
Case Report: Thoracic
Georg Thieme Verlag KG Stuttgart · New York

Surgical Management of Pulmonary Mucormycosis in Third-Trimester Pregnancy

Joel L. Ramirez
1   Department of Surgery, University of California, San Francisco, San Francisco, California, United States
,
Anatoly Urisman
2   Department of Pathology, University of California, San Francisco, San Francisco, California, United States
,
Jasleen Kukreja
1   Department of Surgery, University of California, San Francisco, San Francisco, California, United States
,
Johannes R. Kratz
1   Department of Surgery, University of California, San Francisco, San Francisco, California, United States
› Author Affiliations
Further Information

Publication History

20 March 2018

02 May 2018

Publication Date:
28 June 2018 (online)

Abstract

Background Pulmonary mucormycosis is a rare fungal infection that carries a high mortality. Given the rarity of this disease, its management has not been well established.

Case Description We report a 36-year-old female presenting with right middle and lower lobe pulmonary mucormycosis during the third trimester of pregnancy. Diagnosis was established using chest computed tomography followed by bronchoalveolar lavage and lung biopsy. Prompt initiation of amphotericin B and right middle and lower lobe lobectomy resulted in maternal survival and fetal viability.

Conclusion This favorable outcome is attributed to extensive communication between treatment teams in addition to comprehensive surgical planning.

 
  • References

  • 1 Petrikkos G, Skiada A, Lortholary O, Roilides E, Walsh TJ, Kontoyiannis DP. Epidemiology and clinical manifestations of mucormycosis. Clin Infect Dis 2012; 54 (Suppl. 01) S23-S34
  • 2 Torres-Narbona M, Guinea J, Martínez-Alarcón J, Muñoz P, Gadea I, Bouza E. ; MYCOMED Zygomycosis Study Group. Impact of zygomycosis on microbiology workload: a survey study in Spain. J Clin Microbiol 2007; 45 (06) 2051-2053
  • 3 Tedder M, Spratt JA, Anstadt MP, Hegde SS, Tedder SD, Lowe JE. Pulmonary mucormycosis: results of medical and surgical therapy. Ann Thorac Surg 1994; 57 (04) 1044-1050
  • 4 Munoz-Suano A, Hamilton AB, Betz AG. Gimme shelter: the immune system during pregnancy. Immunol Rev 2011; 241 (01) 20-38
  • 5 Connor BA, Anderson RJ, Smith JW. Mucor mediastinitis. Chest 1979; 75 (04) 525-526
  • 6 McAdams HP, Rosado de Christenson M, Strollo DC, Patz Jr EF. Pulmonary mucormycosis: radiologic findings in 32 cases. AJR Am J Roentgenol 1997; 168 (06) 1541-1548