Response of Femoral Venous Oxygen Tension to Graduated Pressure Stockings - Possible Relationship to Deep Vein Thrombosis

G C Okoye; J H Evans; J Beattie; G D O Lowe; A R Lorimer; C D Forbes

doi:10.1055/s-0038-1661031

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1984; 51(01): 103-104
DOI: 10.1055/s-0038-1661031

Original Article

Schattauer GmbH Stuttgart

Response of Femoral Venous Oxygen Tension to Graduated Pressure Stockings - Possible Relationship to Deep Vein Thrombosis

G C Okoye

The Bioengineering Unit, University of Strathclyde, Glasgow and the University Departments of Medicine and Medical Cardiology, Royal Infirmary, Glasgow, Great Britain

,

J H Evans

The Bioengineering Unit, University of Strathclyde, Glasgow and the University Departments of Medicine and Medical Cardiology, Royal Infirmary, Glasgow, Great Britain

,

J Beattie

The Bioengineering Unit, University of Strathclyde, Glasgow and the University Departments of Medicine and Medical Cardiology, Royal Infirmary, Glasgow, Great Britain

,

G D O Lowe

The Bioengineering Unit, University of Strathclyde, Glasgow and the University Departments of Medicine and Medical Cardiology, Royal Infirmary, Glasgow, Great Britain

,

A R Lorimer

The Bioengineering Unit, University of Strathclyde, Glasgow and the University Departments of Medicine and Medical Cardiology, Royal Infirmary, Glasgow, Great Britain

,

C D Forbes

The Bioengineering Unit, University of Strathclyde, Glasgow and the University Departments of Medicine and Medical Cardiology, Royal Infirmary, Glasgow, Great Britain

› Author Affiliations

Abstract

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Summary

Venous oxygen tension (pO₂) was measured in discrete samples of blood obtained through the femoral vein of cardiac catheterisation patients before, during and after application of sustained external graduated pressure in the form of compression stockings (T. E. D. Kendall). There was a significant reduction (p <0.05) of pO₂ from the baseline value both 30 sec and one minute after the application of the pressure stockings. Thereafter, the pO₂ rose to baseline values. Two minutes after the stockings were removed there was again a significant reduction (p <0.05) of pO₂ from the baseline value. We suggest that the decrease in ivenous pO₂ on application of external pressure may be a reflection of washing out of stagnant hypoxic blood from the venous valve pockets, which may be related to the formation of deep vein thrombosis (DVT).

Key Words

Oxygen tension - Pressure stockings - Deep vein thrombosis

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References

References
1 Sigel B, Edelstein AL, Savitch L, Hasty JH, Felix WR. Type of compression for reducing venous stasis. Arch Surg 1975; 110: 171-175
2 Wilkins RW, Mixtex Jr G, Stanton JR, Litten J. Elastic stockings in the prevention of pulmonary embolism - a preliminary report. N Engl J Med 1952; 246: 360-364
3 Husni EA, Ximes JO C, Goyette EM. Elastic support of the lower limbs in hospital patients. JAMA 1970; 214: 1456-1462
4 Holford CP, Bliss BP. The effect of graduated static compression on isotopically diagnosed deep vein thrombosis of the leg. Br J Surg 1976; 157
5 Bolton J. The prevention of post-operative deep venous thrombosis by graduated compression stockings. Scott Med J 1977; 23: 315-317
6 Hills NH, Pflug JJ, Jeyasingh K, Boardman L, Calnan JS. Prevention of deep vein thrombosis by intermittent pneumatic compression of the calf. Br J Med 1977; 1: 131-135
7 Allenby F, Boardman L, Pflug JJ, Calnan JS. Effects of external compression on fibrinolysis in man. Lancet 1973; 1: 1412-1414
8 Knight MT N, Dawson R. Reduction of the incidence of deep vein thrombosis (DVT) in the legs by intermittent compression of the arms. Br J Surg 1976; 63: 668
9 Cotton LT, Roberts VC. Prevention of post-operative deep vein thrombosis by intermittent compression of the legs. In: Venous Problems. Bergan JJ, Yao JS T. eds Year Book Medical Publishers Inc; New York: 1978. pp 553-557
10 DeBoer AC, Turpie AG G, Butt R, Genton E. The contribution oi increased fibrinolysis induced by intermittent pneumatic compression of the legs in the prevention of deep vein thrombosis. Thromt Haemostas 1981; 46: 191 (Abstr.)
11 Nicolaides AN, Fernandes H, Pollock AV, Eastcott HH G. Intermittent sequential pneumatic compression of the legs in the prevention of venous stasis and post-operative deep vein thrombosis. In: Non-invasive cardiovascular diagnosis. 2nd edition. Dietrich EB. (ed) Mass PSG Publ Co Inc; Littleton: 1981. pp 299-331
12 Scurr JH, Bucknall TE, Ellis H, Wastell C. Sequential pneumatic compression - an effective method of preventing deep venous thrombosis. Thromb Haemostas 1981; 46: 191 (Abstr.)
13 Hartman JT, Yost RP, Robertson WW, Janssen HF. Evaluation o thigh length sequential leg compression in the prevention of deej venous thrombosis. Thromb Haemostas 1981; 46: 400 (Abstr.)
14 Sabri S, Roberts VC, Cotton LT. Prevention of early post-operative deep vein thrombosis by passive exercise of the leg during surgery. Bi Med J 1971; 3: 82-83
15 Doran FS A, Drury M, Sivyer AL. A simple way to combat the venous stasis which occurs during surgical operations in the lowe: limbs. Br J Surg 1964; 51: 486-492
16 Browse NL, Negus D. Prevention of post-operative leg vein throm bosis by electrical muscle stimulation. An evaluation with¹²⁵I labellee fibrinogen Br Med J 1970; 3: 615-618
17 Roberts VC, Sabri S, Beeley AH, Cotton LT. The effect o intermittently applied pressure on the haemodynamics of the lowe limb in man. Br J Surg 1972; 59: 223-226
18 Sabri S, Roberts VC, Cotton LT. The effects of intermittently appliei external pressure on the haemodynamics of the hind limb in grey hound dogs. Br J Surg 1972; 59: 219-222
19 Hamer JD, Malone PC, Silver IA. The pO₂ in venous valve pockets its possible bearing on thrombogenesis. Br J Surg 1981; 68: 166-170