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Thromb Haemost 1984; 51(03): 376-378
DOI: 10.1055/s-0038-1661105
Original Article
Schattauer GmbH Stuttgart

The Establishment of a Standard for Plasminogen (Glu-Type)

P J Gaffney
National Institute for Biological Standards and Control, London, U.K.
,
A D Curtis
*   The Division of Blood Products and Statistics Section, London, U.K.
› Author Affiliations
Further Information

Publication History

Received 12 March 1984

Accepted 06 April 1984

Publication Date:
19 July 2018 (online)

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Summary

Following an international collaborative study, a preparation of glutamic acid-(glu-)human plasminogen was established as a British Standard. This study compared the activity of the proposed standard following full activation to plasmin with the 2nd International Reference Preparation (IRP) for plasmin using both fibrinolytic and chromogenic assays. There was good agreement between the results of the two assay methods. The activity of the standard was 10 units per ampoule, these units being equivalent to those defined by the 2nd IRP for plasmin.

Keywords

Plasminogen - Collaborative study - British Standard
 

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