Des-Amino-D-Arginine Vasopressin Does Not Increase Circulating Levels of Prostacyclin or Thromboxane A2 During Infusion in Man

Thromb Haemost 1983; 50(02): 622
DOI: 10.1055/s-0038-1665270

Letter to the Editor

Schattauer GmbH Stuttgart

Des-Amino-D-Arginine Vasopressin Does Not Increase Circulating Levels of Prostacyclin or Thromboxane A₂ During Infusion in Man

S E Barrow

Department of Clinical Pharmacology, Royal Postgraduate Medical School, London W12 OHS, U.K.
D J Heavey

Department of Clinical Pharmacology, Royal Postgraduate Medical School, London W12 OHS, U.K.
E Jacqz

Department of Clinical Pharmacology, Royal Postgraduate Medical School, London W12 OHS, U.K.
I A Blair

Department of Clinical Pharmacology, Royal Postgraduate Medical School, London W12 OHS, U.K.
C T Dollery

Department of Clinical Pharmacology, Royal Postgraduate Medical School, London W12 OHS, U.K.

References
1 Greaves M, Preston FE. Plasma 6-keto-prostaglandin F_lα: fact or fiction. Thromb Res 1982; 26: 145-157
2 Belch JJ F, Small M, McKenzie F, Hill PA, Lowe GD O, McIntyre DE, Forbes CD, Prentice CR M. DDAVP stimulates prostacyclin production. Thromb Haemostas 1982; 47: 122-123
3 D’Angelo A, Capitanio A, Smith JB, Valsecchi C, Mannucci PM. Effect of Des-Amino-D-Arginine Vasopressin (DDAVP) on plasma levels of platelet and endothelial cell release products. Thromb Haemostas 1983; 49: 64
4 Belch JJ F, McLaren M, Lowe GD O, McIntyre DE, Forbes CD, Prentice CR M. Effect of Des-Amino-D-Arginine Vasopressin (DDAVP) on plasma levels of platelet and endothelial cell release products - Reply. Thromb Haemostas 1983; 49: 65
5 Blair IA, Barrow SE, Waddell KA, Lewis PJ, Dollery CT. Prostacyclin is not a circulating hormone in man. Prostaglandins 1982; 23: 579-589
6 Ritter JM, Barrow SE, Blair IA, Dollery CT. Release of prostacyclin in vivo and its role in man. Lancet 1983; 1: 317-319
7 Barrow SE, Waddell KA, Ennis M, Dollery CT, Blair IA. Analysis of picomolar concentrations of 6-oxo-prostaglandin Fla in biological fluids. J Chromatogr 1982; 239: 71-80
8 Dollery CT, Barrow SE, Blair IA, Lewis PJ, MacDermot J, Orchard MA, Ritter J, Robinson C, Shepherd GL, Waddell K, Allision DJ. The role of prostacyclin. In Atherosclerosis: Mechanisms and Approaches to Therapy. Miller NE. (Ed) pp 105-123 1983. Raven Press; New York: