Abstract
Background Valve sparing aortic root repair by reimplantation (David procedure) is an established
technique in acute aortic dissection Stanford type A involving the aortic root. In
DeBakey type I dissection, aortic arch replacement using the frozen elephant trunk
(FET) was introduced to promote aortic remodeling of the downstream aorta. The combination
of these two complex procedures represents a challenging surgical strategy and was
considered too risky so far.
Methods All patients with acute aortic dissection DeBakey type I undergoing valve sparing
aortic root repair by reimplantation technique of David combined with extended aortic
repair using the FET at our center between October 2009 and December 2016 were evaluated.
Outcomes are compared with patients who underwent prosthetic aortic root replacement
and FET for aortic dissection in the same timeframe.
Results A total of 28 patients received combined David and FET procedure, while 20 patients
received prosthetic aortic root replacement and FET procedure. Thirty-day mortality
was 10.7% (n = 3) for the David group and 20% (n = 4) for the root replacement group (p = 0.43). Postoperative echocardiographic control revealed an excellent aortic valve
function with regurgitation grade 0° or maximum grade I° and a mean gradient of 4.3 ± 2.1 mm
Hg in all patients in the David group versus 7.2 ± 2.4 mm Hg in the aortic root replacement
group, p = 0.003. Computed tomography angiography scan showed positive aortic remodeling in
all but three patients (91.9%). Mid-term follow-up survival was 82.1% in the David
group and 68.4% in the root replacement group, p = 0.28. There was no need for reintervention at the root or descending aorta.
Conclusion Simultaneous application of the David and FET procedure in patients with acute aortic
dissection is safe and feasible in experienced hands as compared with standard aortic
root replacement plus FET. The mid-term outcomes are encouraging and noninferior to
conventional surgery results.
Keywords
aorta/aortic - Aortic valve and root - outcomes