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DOI: 10.1055/s-0038-1668173
Olfactory Groove Schwannoma—A Case Report and Literature Review
Schwannoma de Goteira Olfatória—Relato de Caso e Revisão de LiteraturaPublication History
01 February 2018
08 June 2018
Publication Date:
20 August 2018 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00028832/201803/lookinside/thumbnails/10-1055-s-0038-1668173_1800013-1.jpg)
Abstract
Olfactory groove schwannomas (OGSs) are rare benign tumors of the anterior skull base region. Considering the lack of Schwann cells in the optic and olfactory nerves, their origin remains enigmatic. Despite the precursor cell, total resection of the lesion is curative, as long as the histopathological features of the tumor are compatible with schwannoma. We report the case of a 32-year-old woman, addicted to crack, who was brought to the hospital presenting with cognitive dysfunction after being physically assaulted, whose neuroimaging revealed a large extra-axial mass in the subfrontal sagittal region. The presentation, immunohistochemical markers and histogenesis are discussed in the present study, along with a literature review.
Resumo
O schwannoma da goteira olfatória (SGO) é um tipo de tumor raro da região anterior da base do crânio. Devido à inexistência de células de Schwann nos nervos óptico e olfatório, a origem desses tumores permanece enigmática. Independentemente da célula precursora, a ressecção total do tumor demonstrou ser curativa, desde que o tumor apresente características histopatológicas condizentes com schwannoma. Relatamos aqui o caso de uma mulher de 32 anos, dependente de crack, que foi trazida ao hospital apresentando disfunção cognitiva após sofrer agressão física. A neuroimagem revelou uma grande massa extra-axial se estendendo desde a goteira olfatória até a região entre os hemisférios frontais. A paciente foi submetida a tratamento cirúrgico, e o tumor foi removido completamente. A apresentação clínica, marcadores imunohistoquímicos e a histopatogênese são discutidos no presente estudo, juntamente com uma revisão da literatura.
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