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Thromb Haemost 2018; 118(12): 2134-2144
DOI: 10.1055/s-0038-1675601
Blood Cells, Inflammation and Infection
Georg Thieme Verlag KG Stuttgart · New York

α1-Antichymotrypsin Present in Therapeutic C1-Inhibitor Products Competes with Selectin–Sialyl LewisX Interaction

Ruchira Engel*
1   Department of Immunopathology, Sanquin Research and Landsteiner Laboratory of the AMC, University of Amsterdam, Amsterdam, The Netherlands
,
Laura Delvasto-Nuñez*
1   Department of Immunopathology, Sanquin Research and Landsteiner Laboratory of the AMC, University of Amsterdam, Amsterdam, The Netherlands
,
Dorina Roem
1   Department of Immunopathology, Sanquin Research and Landsteiner Laboratory of the AMC, University of Amsterdam, Amsterdam, The Netherlands
,
Gerard van Mierlo
1   Department of Immunopathology, Sanquin Research and Landsteiner Laboratory of the AMC, University of Amsterdam, Amsterdam, The Netherlands
,
Stephanie Holst
2   Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands
,
Agnes L. Hipgrave Ederveen
2   Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands
,
Jaap D. van Buul
3   Department of Molecular Cell Biology, Sanquin Research and Landsteiner Laboratory of the AMC, University of Amsterdam, Amsterdam, The Netherlands
,
Manfred Wuhrer
2   Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands
,
Diana Wouters
1   Department of Immunopathology, Sanquin Research and Landsteiner Laboratory of the AMC, University of Amsterdam, Amsterdam, The Netherlands
,
Sacha Zeerleder
1   Department of Immunopathology, Sanquin Research and Landsteiner Laboratory of the AMC, University of Amsterdam, Amsterdam, The Netherlands
4   Department of Hematology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
5   Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
6   Department for BioMedical Research, University of Bern, Bern, Switzerland
› Institutsangaben