RSS-Feed abonnieren
DOI: 10.1055/s-0039-1677742
Could a Titanium Ulnar Shortening Plate Trigger a Metal Allergy? A Case Report
Publikationsverlauf
11. September 2018
21. Dezember 2018
Publikationsdatum:
01. Februar 2019 (online)
Abstract
Background With the growing use of metallic implants, increased research has focused on metal hypersensitivity. The purpose of this case report is to describe a patient with a suspected metal allergy to a titanium plate and to review the literature behind this controversial topic.
Case Description A 45-year-old woman underwent ulnar shortening osteotomy for ulnocarpal abutment. One year later, the patient continued to have chronic pain at the site of the implant, with negative work-up for infection, hardware loosening, or failure. During hardware removal, intraoperative findings revealed titanium particle wear in the surrounding tissues, and subsequent allergy testing revealed a new diagnosis of nickel allergy. Following hardware removal, the patient had complete resolution of her symptoms at 3 months without any recurrence after 12 months from the date of surgery.
Discussion Metals are the most common cause of allergic contact dermatitis. With the increased use of metallic implants, it is no surprise that metal implant allergies have become a cause for concern. While there are multiple tests to try and diagnose a metal implant allergy, there is no gold standard, and results are often difficult to interpret. Physicians need to be cognizant of metal allergies with there often vague symptoms as we continue to search for more reliable and affordable testing.
Clinical Relevance Metal implant allergies can be difficult to diagnose. It is often a diagnosis of exclusion but requires a heightened sense of awareness in the face of a negative work-up with persistent symptoms.
Note
Investigation was performed at the Hand & Upper Extremity Center of Georgia, Atlanta, GA.
-
References
- 1 Basketter DA, Briatico-Vangosa G, Kaestner W, Lally C, Bontinck WJ. Nickel, cobalt and chromium in consumer products: a role in allergic contact dermatitis?. Contact Dermat 1993; 28 (01) 15-25
- 2 Cramers M, Lucht U. Metal sensitivity in patients treated for tibial fractures with plates of stainless steel. Acta Orthop Scand 1977; 48 (03) 245-249
- 3 Gawkrodger DJ. Nickel sensitivity and the implantation of orthopaedic prostheses. Contact Dermat 1993; 28 (05) 257-259
- 4 Merritt K, Rodrigo JJ. Immune response to synthetic materials. Sensitization of patients receiving orthopaedic implants. Clin Orthop Relat Res 1996; (326) 71-79
- 5 Haudrechy P, Foussereau J, Mantout B, Baroux B. Nickel release from nickel-plated metals and stainless steels. Contact Dermat 1994; 31 (04) 249-255
- 6 Kanerva L, Sipiläinen-Malm T, Estlander T, Zitting A, Jolanki R, Tarvainen K. Nickel release from metals, and a case of allergic contact dermatitis from stainless steel. Contact Dermat 1994; 31 (05) 299-303
- 7 Matthew I, Frame JW. Allergic responses to titanium. J Oral Maxillofac Surg 1998; 56 (12) 1466-1467
- 8 Müller K, Valentine-Thon E. Hypersensitivity to titanium: clinical and laboratory evidence. Neuroendocrinol Lett 2006; 27 (Suppl. 01) 31-35
- 9 Sicilia A, Cuesta S, Coma G. , et al. Titanium allergy in dental implant patients: a clinical study on 1500 consecutive patients. Clin Oral Implants Res 2008; 19 (08) 823-835
- 10 Lalor PA, Revell PA, Gray AB, Wright S, Railton GT, Freeman MA. Sensitivity to titanium. A cause of implant failure?. J Bone Joint Surg Br 1991; 73 (01) 25-28
- 11 Harloff T, Hönle W, Holzwarth U, Bader R, Thomas P, Schuh A. Titanium allergy or not? Impurity of titanium implant materials. Health 2010; 2: 306-310
- 12 Hallab N, Merritt K, Jacobs JJ. Metal sensitivity in patients with orthopaedic implants. J Bone Joint Surg Am 2001; 83-A (03) 428-436
- 13 Atanaskova Mesinkovska N, Tellez A, Molina L. , et al. The effect of patch testing on surgical practices and outcomes in orthopedic patients with metal implants. Arch Dermatol 2012; 148 (06) 687-693
- 14 Basko-Plluska JL, Thyssen JP, Schalock PC. Cutaneous and systemic hypersensitivity reactions to metallic implants. Dermatitis 2011; 22 (02) 65-79
- 15 Hallab NJ, Jacobs JJ. Biologic effects of implant debris. Bull NYU Hosp Jt Dis 2009; 67 (02) 182-188
- 16 Mark BJ, Slavin RG. Allergic contact dermatitis. Med Clin North Am 2006; 90 (01) 169-185
- 17 Christensen TJ, Samant SA, Shin AY. Making sense of metal allergy and hypersensitivity to metallic implants in relation to hand surgery. J Hand Surg Am 2017; 42 (09) 737-746
- 18 Nelson JL, Mowad CM. Allergic contact dermatitis: patch testing beyond the TRUE test. J Clin Aesthet Dermatol 2010; 3 (10) 36-41
- 19 Lohmann CH, Hameister R, Singh G. Allergies in orthopaedic and trauma surgery. Orthop Traumatol Surg Res 2017; 103 (1S): S75-S81