Mental Health Disorders Associated with Sinonasal and Skull Base Malignancies: A Large Cohort Study

Ji Hyae Lee; Brad E. Zacharia; Djibril Ba; Douglas Leslie; Guodong Liu; Neerav Goyal

doi:10.1055/s-0039-1679889

Journal of Neurological Surgery Part B: Skull Base, Inhaltsverzeichnis

J Neurol Surg B Skull Base 2020; 81(02): 187-192
DOI: 10.1055/s-0039-1679889

Original Article

Georg Thieme Verlag KG Stuttgart · New York

Mental Health Disorders Associated with Sinonasal and Skull Base Malignancies: A Large Cohort Study

Autoren

Ji Hyae Lee

¹The Pennsylvania State University, College of Medicine, Hershey, Pennsylvania, United States
Brad E. Zacharia

²Department of Neurosurgery, The Pennsylvania State University, College of Medicine, Hershey, Pennsylvania, United States
Djibril Ba

³Department of Public Health Sciences, The Pennsylvania State University, College of Medicine, Hershey, Pennsylvania, United States
Douglas Leslie

³Department of Public Health Sciences, The Pennsylvania State University, College of Medicine, Hershey, Pennsylvania, United States
Guodong Liu

³Department of Public Health Sciences, The Pennsylvania State University, College of Medicine, Hershey, Pennsylvania, United States
Neerav Goyal

⁴Division of Otolaryngology – Head and Neck Surgery, Department of Surgery, The Pennsylvania State University, College of Medicine, Hershey, Pennsylvania, United States

Abstract

Objective The main purpose of this article is to examine the prevalence, incidence, sociodemographic, and clinical characteristics of mental health disorders (MHDs) among patients with skull base malignancies.

Design Retrospective cohort study.

Settings/Participants Six-thousand seven-hundred sixty sinonasal/skull base cancer patients in the MarketScan database between 2005 and 2014.

Main Outcome Measures Frequency of MHDs pre- and post-diagnosis in patients harboring sinonasal/skull base malignancies.

Results A significant increase in MHDs was noted from pre- to post-cancer diagnosis (22 vs 31%, p < 0.0001). Despite an increase in the prevalence rate, the demographic profile of patients with MHDs post-diagnosis remained similar to pre-diagnosis. Those patients harboring MHDs were, however, more likely to be women (62.7 vs 47.4%), and carry a history of smoking (40.9 vs 26.3%) than those without MHDs. These comparisons were statistically significant (p < 0.0001).

Conclusion The prevalence of MHDs increases following a diagnosis of a sinonasal/skull base malignancy. Patients with MHDs were more likely to be women and smokers.

Keywords

sinonasal cancer - skull base cancer - mental health disorders - survivorship

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Referenzen

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