Endoscopy 2019; 51(04): S103
DOI: 10.1055/s-0039-1681474
ESGE Days 2019 oral presentations
Saturday, April 6, 2019 11:00 – 13:00: ESD stomach 2 Club A
Georg Thieme Verlag KG Stuttgart · New York

FEASIBILITY AND LONG-TERM EFFICACY OF ENDOSCOPIC TREATMENT OF GASTROINTESTINAL STROMAL TUMORS IN UPPER GASTROINTESTINAL TRACT

JJ Park
1   Gastroenterology, Korea University Guro Hospital, Seoul, Korea, Republic of
,
JS Koh
1   Gastroenterology, Korea University Guro Hospital, Seoul, Korea, Republic of
,
MK Joo
1   Gastroenterology, Korea University Guro Hospital, Seoul, Korea, Republic of
,
BJ Lee
1   Gastroenterology, Korea University Guro Hospital, Seoul, Korea, Republic of
,
HJ Chun
2   Gastroenterology, Korea University Anam Hospital, Seoul, Korea, Republic of
,
SW Lee
3   Gastroenterology, Korea University Ansan Hospitals, Ansan, Korea, Republic of
,
CH Yang
4   Internal Medicine, Dongguk University Gyeongju Hospital, Gyeongju, Korea, Republic of
,
EY Kim
5   Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea, Republic of
› Author Affiliations
Further Information

Publication History

Publication Date:
18 March 2019 (online)

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Aims:

Endoscopic resection has been introduced for the treatment of subepithelial tumors (SETs) in the upper gastrointestinal tract (UGIT). We aimed in this study to investigate the feasibility and long-term efficacy of endoscopic resection of gastrointestinal stromal tumor (GIST) in UGIT.

Methods:

Between March 2005 and February 2018, 126 cases of GIST in UGIT were resected. We retrospectively analyzed clinicopathologic parameters and recurrence rate.

Results:

Mean age was 57.6 ± 12.4 years, and male: female ratio was 50:76. Fifty-one tumors (40.5%) were located in the 40.5% on body of stomach, followed by 34 (27.0%) on fundus, 24 (19.0%) on cardia, and 16 (12.7%) on antrum. One hundred four cases (82.5%) was resected by endoscopic submucosal dissection, followed by endoscopic mucosal resection in 10 (7.9%), and endoscopic submucosal tunnel dissection in eight (6.3%). Endoscopic full thickness resection was performed in three cases (2.4%). In terms of complication, eight macroperforation (6.3%), eight microperforation (6.3%), and seven major bleeding (5.6%) were noted. According to the National Institutes of Health classification, 64 patients (50.8%) were corresponding to very low risk, followed by low risk 42 (33.3%), intermediate risk 14 (11.1%) and high risk six (4.8%). En bloc resection rate was 72.2% (91/126), and R0 resection rate was 22.2% (28/126). R1 resection rate was 68.3% (86/126) and R2 resection rate was 7.1% (9/126). Among 68 patients who were followed-up longer than 12 months, two patients (2.9%) showed recurrence during 31.7 months of follow-up period.

Conclusions:

Endoscopic resection of GIST appears to be a feasible procedure with relatively low rate of recurrence, even low R0 resection rate.