Endoscopy 2019; 51(04): S159
DOI: 10.1055/s-0039-1681639
ESGE Days 2019 ePoster podium presentations
Friday, April 5, 2019 14:00 – 14:30: Stomach ESD ePoster Podium 8
Georg Thieme Verlag KG Stuttgart · New York

EARLY GASTRIC CANCERS FREQUENTLY RECUR IN PATIENTS WITH LIVER CIRRHOSIS (LC) COMPARED WITH NON-LC PATIENTS

MK Joo
1   Gastroenterology, Korea University Guro Hospital, Seoul, Korea, Republic of
,
CH Yang
2   Internal Medicine, Dongguk University Gyeongju Hospital, Gyeongju, Korea, Republic of
,
JS Koh
1   Gastroenterology, Korea University Guro Hospital, Seoul, Korea, Republic of
,
BJ Lee
1   Gastroenterology, Korea University Guro Hospital, Seoul, Korea, Republic of
,
JJ Park
1   Gastroenterology, Korea University Guro Hospital, Seoul, Korea, Republic of
,
HJ Chun
3   Gastroenterology, Korea University Anam Hospital, Seoul, Korea, Republic of
,
SW Lee
4   Gastroenterology, Korea University Ansan Hospitals, Ansan, Korea, Republic of
› Institutsangaben
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Publikationsverlauf

Publikationsdatum:
18. März 2019 (online)

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Aims:

Aims We investigated clinical efficacy, safety and long-term follow-up outcomes of early gastric cancer (EGC) treated by endoscopic resection in patients with liver cirrhosis (LC), by comparing with non-LC patients.

Methods:

From March 2007 to March 2016, EGC patients who had underlying LC and underwent endoscopic treatment at our institute were enrolled (LC-EGC group). Clinical and histopathologic short-term outcomes and long-term follow-up outcomes were compared with EGC patients without LC (non-LC-EGC group).

Results:

Seventeen EGC lesions in 14 patients LC were resected by endoscopic procedure for the treatment of EGC. Male were 85.7% (12/14), alcohol was the most common cause of LC (10/14, 71.4%), and 10 patients (71.4%) were corresponding to decompensated LC. When we compared LC-EGC group with non-LC-EGC group (665 EGC lesions in 640 patients), baseline characteristics (age, sex, comorbidities), characteristics of tumor (size, groß type, location), short-term outcomes (en bloc resection rate, complete resection rate, curative resection rate) and histopathology (differentiation, submucosal invasion, lymphovascular involvement) were not significantly different in both groups. However, recurrence of entire cancer (30.8% vs. 5.3%, p < 0.001), synchronous cancer (15.4% vs. 2.0%, p = 0.001) and metachronous cancer (15.4% vs. 3.3%, p = 0.019) were significantly higher in LC-EGC group than non-LC-EGC group.

Conclusions:

Endoscopic resection of EGC in LC patient is an effective and safe modality. However, physicians may pay attention to the recurrence of cancer during clinical follow- up.