Endoscopy 2019; 51(04): S161
DOI: 10.1055/s-0039-1681646
ESGE Days 2019 ePoster podium presentations
Friday, April 5, 2019 16:30 – 17:00: Enteroscopy ePoster Podium 3
Georg Thieme Verlag KG Stuttgart · New York

CORRELATION BETWEEN ENDOSCOPIC FEATURES AND HISTOLOGICAL SUBTYPES OF SMALL INTESTINAL LYMPHOMAS

Y Ueno
1   Kobe City Medical Center General Hospital, Gastroenterology, Kobe, Japan
,
M Fukushima
1   Kobe City Medical Center General Hospital, Gastroenterology, Kobe, Japan
,
S Morita
1   Kobe City Medical Center General Hospital, Gastroenterology, Kobe, Japan
,
S Inoue
1   Kobe City Medical Center General Hospital, Gastroenterology, Kobe, Japan
,
T Inokuma
1   Kobe City Medical Center General Hospital, Gastroenterology, Kobe, Japan
› Institutsangaben
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Publikationsverlauf

Publikationsdatum:
18. März 2019 (online)

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Aims:

A small intestine is a common involved site of malignant lymphomas. With the development of double-balloon endoscopy (DBE), we can evaluate features and take biopsy from small intestinal lymphomas (SIL) less invasively. We investigated the correlation between endoscopic features and histological subtypes of SIL.

Methods:

We retrospectively analyzed 43 SIL patients diagnosed by using DBE at our institution from April 2004 to September 2018.

Results:

The median age was 66 years (range 29 – 89 years) and 28 were males. Involved sites included duodenum in 1 patient, jejunum in 18, ileum in 8 and broad small intestine in 16. Histological subtypes were as follows; FL (N = 18), DLBCL (N = 17), MEITL (N = 3), anaplastic large cell lymphoma (N = 2), adult T-cell leukemia-lymphoma (N = 1), extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue type (N = 1), mantle cell lymphoma (N = 1). In Lugano classification, 18 patients were at stage I, 6 at stage II1, 4 at stage II2, 5 at stage IIE, 10 at stage IV.

As regards endoscopic features, FL presented as mainly multiple lymphomatous polyposis type (N = 16), DLBCL as ulcer type (N = 11), MEITL mixed type (N = 3).

*follicular lymphoma (FL), diffuse large B-cell lymphoma (DLBCL), monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL).

Conclusions:

There is a tendency between endoscopic features and histological subtypes. Pathological grounds are needed for each definitive diagnosis, but we can predict a subtype of malignant lymphoma based on endoscopic features. DBE is useful for diagnosis with malignant lymphoma in terms of observation of morphologic features and pathological and histological findings by biopsy.