Clinical Strategies to Prevent Acute Respiratory Distress Syndrome

Yewande E. Odeyemi; Svetlana Herasevich; Michelle N. Gong; Ognjen O. Gajic

doi:10.1055/s-0039-1683997

Seminars in Respiratory and Critical Care Medicine, Table of Contents

Semin Respir Crit Care Med 2019; 40(01): 129-136
DOI: 10.1055/s-0039-1683997

Review Article

Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Clinical Strategies to Prevent Acute Respiratory Distress Syndrome

Authors

Yewande E. Odeyemi

¹Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota
Svetlana Herasevich

¹Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota
Michelle N. Gong

²Division of Critical Care Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York
Ognjen O. Gajic

¹Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota

Abstract

Acute respiratory distress syndrome (ARDS) remains an important clinical entity in the intensive care unit with a significant impact on morbidity and mortality. Effective therapeutic interventions are limited; thus current research focus has shifted from treatment to the prevention of this pulmonary syndrome. In recent decades, a decrease in the incidence of ARDS has been observed and this reduction is largely due to preventive strategies including safe lung ventilation practices, avoidance of iatrogenic exposures, and improvement in care of predisposing conditions such as sepsis and pneumonia. Early identification of at-risk patients, prompt treatment of predisposing conditions, and adoption of evidence-based best practice including restrictive transfusion strategies, conservative fluid management, avoidance of large tidal volume ventilation, and aspiration precaution practices are key preventive strategies with demonstrated benefits. There are currently no effective pharmacological preventive strategies for ARDS.

Keywords

acute respiratory distress syndrome - acute lung injury - prevention

Full Text

References

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