CC BY-NC-ND 4.0 · Indian J Plast Surg 2019; 52(01): 045-054
DOI: 10.1055/s-0039-1688097
Review Article
Association of Plastic Surgeons of India

Management of Post-Traumatic Composite Bone and Soft Tissue Defect of Leg

Ravi K. Mahajan
1   Department of Plastic and Reconstructive Surgery, Amandeep Hospital and Clinics, Amritsar, Punjab, India
,
Krishnan Srinivasan
1   Department of Plastic and Reconstructive Surgery, Amandeep Hospital and Clinics, Amritsar, Punjab, India
,
Mahipal Singh
1   Department of Plastic and Reconstructive Surgery, Amandeep Hospital and Clinics, Amritsar, Punjab, India
,
Adish Jain
1   Department of Plastic and Reconstructive Surgery, Amandeep Hospital and Clinics, Amritsar, Punjab, India
,
Taha Kapadia
1   Department of Plastic and Reconstructive Surgery, Amandeep Hospital and Clinics, Amritsar, Punjab, India
,
Ankush Tambotra
1   Department of Plastic and Reconstructive Surgery, Amandeep Hospital and Clinics, Amritsar, Punjab, India
› Author Affiliations
Further Information

Publication History

Publication Date:
08 May 2019 (online)

Abstract

Management of composite defects of leg following trauma requires a planned ortho-plastic approach right from the outset. Timely, planned intervention results in reduced amputation rates and improved limb salvage and function. Right from the time of presentation of the patient to the emergency with such injury, the process of decision making in terms of salvage or amputation, local flap cover/free flap cover, bone reconstruction first or soft tissue or both combined, come into play. Guidelines on management are unclear for such defects, a literature search yielding various methods being used by different authors.

This article is a review of current literature on management of composite leg defects.

A summary of the literature search in terms of various management options given by various authors including the rationale, advantages and disadvantages of each strategy has been provided in this article. The management protocol and method followed by the author in his institute for management of such composite defects have been described in detail. The article seeks to provide readers with an understanding of the management strategies so that appropriate method could be chosen to provide best result.

 
  • References

  • 1 World Health Organization. Global Status Report on Road Safety: Time for Action. Geneva, Switzerland: WHO; 2009
  • 2 Ameratunga S, Hijar M, Norton R. Road-traffic injuries: confronting disparities to address a global-health problem. Lancet 2006; 367 9521 1533-1540
  • 3 Townley WA, Urbanska C, Dunn RL, Khan U. Costs and coding–free-flap reconstruction in lower-limb trauma. Injury 2011; 42 (04) 381-384
  • 4 Pollak AN, Jones AL, Castillo RC, Bosse MJ, MacKenzie EJ. LEAP Study Group. The relationship between time to surgical debridement and incidence of infection after open high-energy lower extremity trauma. J Bone Joint Surg Am 2010; 92 (01) 7-15
  • 5 Kim PH, Leopold SS. In brief: Gustilo-Anderson classification. [corrected]. Clin Orthop Relat Res 2012; 470 (11) 3270-3274
  • 6 Swartz WM, Mears DC. The role of free-tissue transfers in lower-extremity reconstruction. Plast Reconstr Surg 1985; 76 (03) 364-373
  • 7 Prasarn ML, Helfet DL, Kloen P. Management of the mangled extremity. Strateg Trauma Limb Reconstr 2012; 7 (02) 57-66
  • 8 Akula M, Gella S, Shaw CJ, McShane P, Mohsen AM. A meta-analysis of amputation versus limb salvage in mangled lower limb injuries–the patient perspective. Injury 2011; 42 (11) 1194-1197
  • 9 Soltanian H, Garcia RM, Hollenbeck ST. Current concepts in lower extremity reconstruction. Plast Reconstr Surg 2015; 136 (06) 815e-829e
  • 10 Lange RH. Limb reconstruction versus amputation decision making in massive lower extremity trauma. Clin Orthop Relat Res 1989; (243) 92-99
  • 11 Bosse MJ, McCarthy ML, Jones AL. et al; Lower Extremity Assessment Project (LEAP) Study Group. The insensate foot following severe lower extremity trauma: an indication for amputation?. J Bone Joint Surg Am 2005; 87 (12) 2601-2608
  • 12 Bonanni F, Rhodes M, Lucke JF. The futility of predictive scoring of mangled lower extremities. J Trauma 1993; 34 (01) 99-104
  • 13 Oliver AS, Ian DC. The New injury severity score vs the injury severity score in predicting patient outcome. A comparative evaluation on trauma service patients of Auckland hospital. Annu Proc Assoc Adv Automot Med 1999; 43: 1-15
  • 14 Rajasekaran S. Ganga Hospital Open Injury Severity Score-a score to prognosticate limb salvage and outcome measures in type IIIb open tibial fractures. Indian J Orthop 2005; 39 (01) 4-13
  • 15 Bosse MJ, MacKenzie EJ, Kellam JF. et al. A prospective evaluation of the clinical utility of the lower-extremity injury-severity scores. J Bone Joint Surg Am 2001; 83-A (01) 3-14
  • 16 Godina M. Early microsurgical reconstruction of complex trauma of the extremities. Plast Reconstr Surg 1986; 78 (03) 285-292
  • 17 Khouri RK, Shaw WW. Reconstruction of the lower extremity with microvascular free flaps: a 10-year experience with 304 consecutive cases. J Trauma 1989; 29 (08) 1086-1094
  • 18 Herter F, Ninkovic M, Ninkovic M. Rational flap selection and timing for coverage of complex upper extremity trauma. J Plast Reconstr Aesthet Surg 2007; 60 (07) 760-768
  • 19 Sabapathy SR. Debridement-preparing the wound bed for cover. In: Sarabahi S, Tiwari VK. eds. Principles and Practice of Wound Care. 1st ed.. New Delhi: Jaypee Brothers and VK; 2012: 71
  • 20 Granick MS, Tenenhaus M, Knox KR, Ulm JP. Comparison of wound irrigation and tangential hydrodissection in bacterial clearance of contaminated wounds: results of a randomized, controlled clinical study. Ostomy Wound Manage 2007; 53 (04) 64-66 68–70, 72
  • 21 Granick M, Boykin J, Gamelli R, Schultz G, Tenenhaus M. Toward a common language: surgical wound bed preparation and debridement. Wound Repair Regen 2006; 14 (Suppl. 01) S1-S10
  • 22 Zierenberg GarcíaC, Beaton ComuladaD, Pérez LópezJC. et al. Acute shortening and re-lengthening in the management of open tibia fractures with severe bone of 14 CMS or more and extensive soft tissue loss. Bol Asoc Med P R 2016; 108 (01) 91-94
  • 23 Kevin T, Cengiz S, John HE. et al. Bone transport versus acute shortening for the management of infected tibial non-unions with bone defects. Injury 10.1016/j.injury.2017.07.018
  • 24 Yazar S, Lin CH, Wei FC. One-stage reconstruction of composite bone and soft-tissue defects in traumatic lower extremities. Plast Reconstr Surg 2004; 114 (06) 1457-1466
  • 25 Knobloch K, Herold C, Vogt PM. [Free latissimus dorsi flap transfer for reconstruction of soft tissue defects of the lower extremity]. Oper Orthop Traumatol 2012; 24 (02) 122-130
  • 26 Heller L, Levin LS. Lower extremity microsurgical reconstruction. Plast Reconstr Surg 2001; 108 (04) 1029-1041 quiz 1042
  • 27 Dendrinos GK, Kontos S, Katsenis D, Dalas A. Treatment of high-energy tibial plateau fractures by the Ilizarov circular fixator. J Bone Joint Surg Br 1996; 78 (05) 710-717
  • 28 Gulsen M, Ozkan C. Angular shortening and delayed gradual distraction for the treatment of asymmetrical bone and soft tissue defects of tibia: a case series. J Trauma 2009; 66 (05) E61-E66
  • 29 Yokoyama K, Itoman M, Nakamura K, Uchino M, Tsukamoto T, Suzuki T. Primary shortening with secondary limb lengthening for Gustilo IIIB open tibial fractures: a report of six cases. J Trauma 2006; 61 (01) 172-180
  • 30 Sen C, Kocaoglu M, Eralp L, Gulsen M, Cinar M. Bifocal compression-distraction in the acute treatment of grade III open tibia fractures with bone and soft-tissue loss: a report of 24 cases. J Orthop Trauma 2004; 18 (03) 150-157
  • 31 El-Rosasy MA. Acute shortening and re-lengthening in the management of bone and soft-tissue loss in complicated fractures of the tibia. J Bone Joint Surg Br 2007; 89 (01) 80-88
  • 32 Magadum MP, Basavaraj YadavCM, Phaneesha MS, Ramesh LJ. Acute compression and lengthening by the Ilizarov technique for infected nonunion of the tibia with large bone defects. J Orthop Surg (Hong Kong) 2006; 14: 273-279
  • 33 Yaremchuk MJ. Acute management of severe soft-tissue damage accompanying open fractures of the lower extremity. Clin Plast Surg 1986; 13 (04) 621-632
  • 34 Francel TJ, Vander KolkCA, Hoopes JE, Manson PN, Yaremchuk MJ. Microvascular soft-tissue transplantation for reconstruction of acute open tibial fractures: timing of coverage and long-term functional results. Plast Reconstr Surg 1992; 89 (03) 478-487 discussion 488–489
  • 35 Rodriguez ED, Bluebond-Langner R, Copeland C, Grim TN, Singh NK, Scalea T. Functional outcomes of posttraumatic lower limb salvage: a pilot study of anterolateral thigh perforator flaps versus muscle flaps. J Trauma 2009; 66 (05) 1311-1314
  • 36 Cho EH, Shammas RL, Carney MJ. et al. Muscle versus fasciocutaneous free flaps in lower extremity traumatic reconstruction: a multicenter outcomes analysis. Plast Reconstr Surg 2018; 141 (01) 191-199
  • 37 Wong CH, Ong YS, Wei FC. The anterolateral thigh–vastus lateralis conjoint flap for complex defects of the lower limb. J Plast Reconstr Aesthet Surg 2012; 65 (02) 235-239
  • 38 Gustilo RB, Anderson JT. Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones: retrospective and prospective analyses. J Bone Joint Surg Am 1976; 58 (04) 453-458
  • 39 Raju A, Ooi A, Ong YS, Tan BK. Traumatic lower limb injury and microsurgical free flap reconstruction with the use of negative pressure wound therapy: is timing crucial?. J Reconstr Microsurg 2014; 30 (06) 427-430
  • 40 Starnes-Roubaud MJ, Peric M, Chowdry F. et al. Microsurgical lower extremity reconstruction in the subacute period: a safe alternative. Plast Reconstr Surg Glob Open 2015; 3 (07) e449
  • 41 Tetsworth K, Paley D. Basic science of distraction histogenesis. Curr Opin Orthop 1995; 6: 61-68
  • 42 Ilizarov GA. The tension-stress effect on the genesis and growth of tissues. Part I. The influence of stability of fixation and soft-tissue preservation. Clin Orthop Relat Res 1989; 238: 240-248
  • 43 Mohammad R, Dipak S, Bigyan B, Prem S. Docking site augmentation followed by Ilizarov's distraction osteogenesis. J Orthopaedics Traumatology Rehabilitation 2013; 6 (01) 87-91
  • 44 Paley D, Catagni MA, Argnani F, Villa A, Benedetti GB, Cattaneo R. Ilizarov treatment of tibial nonunions with bone loss. Clin Orthop Relat Res 1989; (241) 146-165
  • 45 Vandenbroucke JP, von Elm E, Altman DG. et al; STROBE Initiative. Strengthening the reporting of observational studies in epidemiology (STROBE): explanation and elaboration. Int J Surg 2014; 12 (12) 1500-1524
  • 46 Hollenbeck ST, Woo S, Ong S, Fitch RD, Erdmann D, Levin LS. The combined use of the Ilizarov method and microsurgical techniques for limb salvage. Ann Plast Surg 2009; 62 (05) 486-491
  • 47 Ilizarov GA. The tension-stress effect on the genesis and growth of tissues. Part I. The influence of stability of fixation and soft-tissue preservation. Clin Orthop Relat Res 1989; (238) 249-281
  • 48 Ong YS, Levin LS. Lower limb salvage in trauma. Plast Reconstr Surg 2010; 125 (02) 582-588
  • 49 Seenappa HK, Shukla MK, Narasimhaiah M. Management of complex long bone nonunions using limb reconstruction system. Indian J Orthop 2013; 47 (06) 602-607
  • 50 Keating JF, Simpson AH, Robinson CM. The management of fractures with bone loss. J Bone Joint Surg Br 2005; 87 (02) 142-150
  • 51 Rohilla R, Wadhwani J, Devgan A, Singh R, Khanna M. Prospective randomised comparison of ring versus rail fixator in infected gap nonunion of tibia treated with distraction osteogenesis. Bone Joint J 2016; 98-B (10) 1399-1405
  • 52 Burghardt RD, Manzotti A, Bhave A, Paley D, Herzenberg JE. Tibial lengthening over intramedullary nails: a matched case comparison with Ilizarov tibial lengthening. Bone Joint Res 2016; 5 (01) 1-10
  • 53 Dickson K, Katzman S, Delgado E, Contreras D. Delayed unions and nonunions of open tibial fractures. Correlation with arteriography results. Clin Orthop Relat Res 1994; (302) 189-193
  • 54 Khatod M, Botte MJ, Hoyt DB, Meyer RS, Smith JM, Akeson WH. Outcomes in open tibia fractures: relationship between delay in treatment and infection. J Trauma 2003; 55 (05) 949-954
  • 55 Gorman PW, Barnes CL, Fischer TJ, McAndrew MP, Moore MM. Soft-tissue reconstruction in severe lower extremity trauma. A review. Clin Orthop Relat Res 1989; (243) 57-64
  • 56 Mahajan RK, Srinivasan K, Bhamre A, Singh M, Kumar P, Tambotra A. A retrospective analysis of latissimus dorsiserratus anterior chimeric flap reconstruction in 47 patients with extensive lower extremity trauma. Indian J Plast Surg 2018; 51 (01) 24-32
  • 57 Jupiter JB, Kour AK, Palumbo MD, Yaremchuk MJ. Limb reconstruction by free-tissue transfer combined with the Ilizarov method. Plast Reconstr Surg 1991; 88 (06) 943-951 discussion 952–954
  • 58 Repo JP, Barner-Rasmussen I, Roine RP, Sintonen H, Tukiainen EJ. Treatment of compound tibia fracture with microvascular latissimus dorsi flap and the Ilizarov technique: a cross-sectional study of long-term outcomes. J Plast Reconstr Aesthet Surg 2016; 69 (04) 524-532
  • 59 Razek AA, Semaya AE. Ilizarov bone transport versus vascularized fibular graft in reconstruction of post-traumatic tibial bone defects. Egypt Orthop J 2013; 48 (01) 5-11
  • 60 Yokoyama K, Itoman M, Nakamura K, Tsukamoto T, Saita Y, Aoki S. Free vascularized fibular graft vs. Ilizarov method for post-traumatic tibial bone defect. J Reconstr Microsurg 2001; 17 (01) 17-25
  • 61 Song HR, Kale A, Park HB. et al. Comparison of internal bone transport and vascularized fibular grafting for femoral bone defects. J Orthop Trauma 2003; 17 (03) 203-211
  • 62 Lin CH, Wei FC, Levin LS. et al. Free composite serratus anterior and rib flaps for tibial composite bone and soft-tissue defect. Plast Reconstr Surg 1997; 99 (06) 1656-1665
  • 63 Babovic S, Johnson CH, Finical SJ. Free fibula donor-site morbidity: the Mayo experience with 100 consecutive harvests. J Reconstr Microsurg 2000; 16 (02) 107-110
  • 64 Beris AE, Lykissas MG, Korompilias AV. et al. Vascularized fibula transfer for lower limb reconstruction. Microsurgery 2011; 31 (03) 205-211
  • 65 Mathoulin C, Gilbert A, Azze RG. Congenital pseudarthrosis of the forear treatment of six cases with vascularized fibular graft and a review of the literature. Microsurgery 1993; 14 (04) 252-259
  • 66 Doi K, Kawakami F, Hiura Y, Oda T, Sakai K, Kawai S. One-stage treatment of infected bone defects of the tibia with skin loss by free vascularized osteocutaneous grafts. Microsurgery 1995; 16 (10) 704-712
  • 67 Malizos KN, Nunley JA, Goldner RD, Urbaniak JR, Harrelson JM. Free vascularized fibula in traumatic long bone defects and in limb salvaging following tumor resection: comparative study. Microsurgery 1993; 14 (06) 368-374
  • 68 de Boer HH, Wood MB. Bone changes in the vascularised fibular graft. J Bone Joint Surg Br 1989; 71 (03) 374-378
  • 69 Lin CH, Wei FC, Chen HC, Chuang DC. Outcome comparison in traumatic lower-extremity reconstruction by using various composite vascularized bone transplantation. Plast Reconstr Surg 1999; 104 (04) 984-992
  • 70 Moran CG, Wood MB. Vascularized bone autografts. Orthop Rev 1993; 22 (02) 187-197
  • 71 Taylor GI, Watson N. One-stage repair of compound leg defects with free, revascularized flaps of groin skin and iliac bone. Plast Reconstr Surg 1978; 61 (04) 494-506
  • 72 Minami A, Ogino T, Itoga H. Vascularized iliac osteocutaneous flap based on the deep circumflex iliac vessels: experience in 13 cases. Microsurgery 1989; 10 (02) 99-102
  • 73 Haddock NT, Wapner K, Levin LS. Vascular bone transfer options in the foot and ankle: a retrospective review and update on strategies. Plast Reconstr Surg 2013; 132 (03) 685-693
  • 74 Bieber EJ, Wood MB. Bone reconstruction. Clin Plast Surg 1986; 13 (04) 645-655
  • 75 Kuokkanen H, Tukiainen E. Soft-tissue and bone reconstruction in compound fractures of the lower leg. Scand J Surg 2003; 92 (04) 265-268
  • 76 Myeroff C, Archdeacon M. Autogenous bone graft: donor sites and techniques. J Bone Joint Surg Am 2011; 93 (23) 2227-2236
  • 77 Mattar JúniorJ, Azze RJ, Ferreira MC, Starck R, Canedo AC. Vascularized fibular graft for management of severe osteomyelitis of the upper extremity. Microsurgery 1994; 15 (01) 22-27
  • 78 Büchler U, Hastings II H. Combined injuries. In: Green DP, Hotchkiss RN, Pederson EC. eds. Green's Operative Hand Surgery. 4th ed.. New York: Churchill Livingstone; 1999: 1631-1650