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Synthesis 2020; 52(03): 337-352
DOI: 10.1055/s-0039-1690733
DOI: 10.1055/s-0039-1690733
short review
Azaheterocyclic Derivatives of ortho-Carborane: Synthetic Strategies and Application Opportunities
The study was supported by the Ministry of Education and Science of the Russian Federation (State contract 4.6351.2017/8.9) and Russian Science Foundation (Project 18-13-00365).Further Information
Publication History
Received: 25 August 2019
Accepted after revision: 03 October 2019
Publication Date:
28 October 2019 (online)
Abstract
Azaheterocyclic derivatives of 1,2-dicarba-closo-dodecaborane (ortho-carborane) are known to be of particular interest due to numerous plausible applications, particularly, in medicine, materials science, and advanced technologies. Three principal synthetic strategies resulting in azaheterocyclic carboranes, in which boron-enriched and azaheterocyclic fragments are linked to each other, either directly by means of the C–C bonds or through a short spacer (CH2, CH2S, CH2O, etc.), have been outlined. These synthetic approaches are of general character and can be used both individually and in combination to afford promising organoboron clusters of diverse architectures.
1 Introduction
2 C–C Cross-Coupling Strategies in the Synthesis of Azaheterocyclic Carboranes
3 Carboryne-Based Transformation Strategies
4 Condensation Strategies: Reactions of Decaborane B10H14 with Substituted Acetylenes
5 Conclusion and Outlook
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