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Synlett 2020; 31(03): 261-266
DOI: 10.1055/s-0039-1691537
DOI: 10.1055/s-0039-1691537
letter
Visible-Light-Induced Arene C(sp2)–H Lactonization Promoted by DDQ and tert-Butyl Nitrite
This project was supported by the National Natural Science Foundation of China (21776260, 21773211 and 21773210) and the Natural Science Foundation of Zhejiang Province (LY17B060007).Weitere Informationen
Publikationsverlauf
Received: 01. November 2019
Accepted after revision: 27. November 2019
Publikationsdatum:
16. Dezember 2019 (online)
Abstract
A visible-light photocatalytic aerobic oxidative lactonization of arene C(sp2)–H bonds proceeds in the presence of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) and tert-butyl nitrite (TBN). Under the optimized conditions, a range of 2-arylbenzoic acids is converted into the corresponding benzocoumarin derivatives in moderate to excellent yields. This method is characterized by its atom economy, mild reaction conditions, the use of a green oxidant and metal-free catalysis.
Key words
photocatalysis - lactonization - 2-arylbenzoic acids - 2,3-dichloro-5,6-dicyano-1,4-benzoquinone - oxygenSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0039-1691537.
- Supporting Information
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