N-Methyl-D-Aspartate Receptor Encephalitis with Psychiatric Symptoms and an Ovarian Teratoma Detected by MRI in a 17-Year-Old Girl

A. Barth; I. Nassenstein; R.B. Tröbs; A. Tannapfel; H. Dercks; K. Rostásy; A. Wegener-Panzer

doi:10.1055/s-0039-1692417

Neuropediatrics, Table of Contents

Neuropediatrics 2019; 50(04): 253-256
DOI: 10.1055/s-0039-1692417

Short Communication

Georg Thieme Verlag KG Stuttgart · New York

N-Methyl-D-Aspartate Receptor Encephalitis with Psychiatric Symptoms and an Ovarian Teratoma Detected by MRI in a 17-Year-Old Girl

A. Barth

¹Department of Pediatric Neurology, Children's Hospital Datteln, University Witten/Herdecke, Germany

,

I. Nassenstein

²Department of Radiology, Children's Hospital Datteln, University Witten/Herdecke, Germany

,

R.B. Tröbs

³Department of Pediatric Surgery, Marien Hospital Herne, Ruhr-University Bochum, Germany

,

A. Tannapfel

⁴Institute of Pathology, Ruhr-University Bochum, Bochum, Germany

,

H. Dercks

⁵Department of Pediatric Child Psychiatry, Children's Hospital Datteln, University Witten/Herdecke, Germany

,

K. Rostásy

¹Department of Pediatric Neurology, Children's Hospital Datteln, University Witten/Herdecke, Germany

,

A. Wegener-Panzer

²Department of Radiology, Children's Hospital Datteln, University Witten/Herdecke, Germany

› Author Affiliations

Abstract

N-methyl-D-aspartate receptor (NMDAR) encephalitis is a rare antibody-mediated autoimmune encephalitis often associated with an ovarian teratoma in adolescent females. Here we present a 17-year-old girl with only and unusual psychiatric symptoms as part of her NMDAR encephalitis in combination with a very small ovarian teratoma suspected by magnetic resonance (MR) imaging and finally histologically confirmed. We further review the literature of NMDAR encephalitis in combination with an ovarian teratoma and discuss the recommended radiological workup in children with a suspected ovarian tumor.

Keywords

NMDA receptor encephalitis - ovarian teratoma - MRI - psychiatric symptoms - laparoscopy - child

Full Text

References

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