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DOI: 10.1055/s-0039-1692448
Current Controversies in Large-Vessel Inflammatory Vasculitis and Thoracic Aortic Aneurysm Disease
Publikationsverlauf
Publikationsdatum:
28. Juni 2019 (online)
![](https://www.thieme-connect.de/media/ija/201904/lookinside/thumbnails/10-1055-s-0039-1692448_190010-1.jpg)
Abstract
Large-vessel vasculitis encompasses the spectrum of vasculitides, which pathologically cause chronic granulomatous inflammatory changes, primarily in the aorta and its major branches. These patients are at risk of developing life-threatening aortic lesions that, without recognition and prompt treatment, can cause detrimental effects. Many provocative issues surrounding large-vessel vasculitis and its surgical treatment still remain, spanning from recognition to management. In this review, we discuss the main large-vessel vasculitides, Takayasu's arteritis and giant cell arteritis. We include the key points and current controversies surrounding diagnostic imaging, timing of interventions, and patient outcomes.
Disclosures
None.
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References
- 1 Mason JC. Takayasu arteritis—advances in diagnosis and management. Nat Rev Rheumatol 2010; 6 (07) 406-415
- 2 Takayasu M. A case with peculiar changes of the retinal central vessels. Acta Soc Ophthal Jpn. 1908; 12: 554-555
- 3 Shimizu K, Sano K. Pulseless disease. J Neuropathol Clin Neurol 1951; 1 (01) 37-47
- 4 Numano F, Kakuta T. Takayasu arteritis—five doctors in the history of Takayasu arteritis. Int J Cardiol 1996; 54 (Suppl): S1-S10
- 5 Mason JC. Takayasu arteritis: surgical interventions. Curr Opin Rheumatol 2015; 27 (01) 45-52
- 6 Ueno A, Awane Y, Wakabayashi A, Shimizu K. Successfully operated obliterative brachiocephalic arteritis (Takayasu) associated with the elongated coarctation. Jpn Heart J 1967; 8 (05) 538-544
- 7 Hellman DB. Giant cell arteritis, polymyalgia rheumatica, and Takayasu's arteritis. In: Firestein GS, Budd RC. , eds. Kelley's Textbook of Rheumatology, 9th ed. Philadelphia, PA: Elsevier Saunders; 2013: 1461-1480
- 8 Sano K, Saito I. Pulseless disease. Summary of our experiences and studies. Schweiz Arch Neurol Neurochir Psychiatr 1972; 111 (02) 417-433
- 9 Ross RS, McKUSICK VA. Aortic arch syndromes; diminished or absent pulses in arteries arising from arch of aorta. AMA Arch Intern Med 1953; 92 (05) 701-740
- 10 Salvarani C, Cantini F, Boiardi L, Hunder GG. Polymyalgia rheumatica and giant-cell arteritis. N Engl J Med 2002; 347 (04) 261-271
- 11 Weyand CM, Goronzy JJ. Giant-cell arteritis and polymyalgia rheumatica. Ann Intern Med 2003; 139 (06) 505-515
- 12 Rahman W, Rahman FZ. Giant cell (temporal) arteritis: an overview and update. Surv Ophthalmol 2005; 50 (05) 415-428
- 13 Koide K. Takayasu arteritis in Japan. Heart Vessels Suppl 1992; 7: 48-54
- 14 Watts R, Al-Taiar A, Mooney J, Scott D, Macgregor A. The epidemiology of Takayasu arteritis in the UK. Rheumatology (Oxford) 2009; 48 (08) 1008-1011
- 15 Waern AU, Andersson P, Hemmingsson A. Takayasu's arteritis: a hospital-region based study on occurrence, treatment and prognosis. Angiology 1983; 34 (05) 311-320
- 16 Reinhold-Keller E, Herlyn K, Wagner-Bastmeyer R, Gross WL. Stable incidence of primary systemic vasculitides over five years: results from the German vasculitis register. Arthritis Rheum 2005; 53 (01) 93-99
- 17 Hall S, Barr W, Lie JT, Stanson AW, Kazmier FJ, Hunder GG. Takayasu arteritis. A study of 32 North American patients. Medicine (Baltimore) 1985; 64 (02) 89-99
- 18 Koide K. Takayasu arteritis in Japan. Heart Vessels Suppl 1992; 7 (Suppl.): 48-54
- 19 Kerr GS, Hallahan CW, Giordano J. , et al. Takayasu arteritis. Ann Intern Med 1994; 120 (11) 919-929
- 20 Gulati A, Bagga A. Large vessel vasculitis. Pediatr Nephrol 2010; 25 (06) 1037-1048
- 21 Hutchinson J. Diseases of the arteries. On a peculiar form of thrombotic arteritis of the aged which is sometimes productive of gangrene. Arch Surg 1890; 1: 323-329
- 22 Goodwin JS. Progress in gerontology: polymyalgia rheumatica and temporal arteritis. J Am Geriatr Soc 1992; 40 (05) 515-525
- 23 Kobayashi S, Fujimoto S. Epidemiology of vasculitides: differences between Japan, Europe and North America. Clin Exp Nephrol 2013; 17 (05) 611-614
- 24 Nordborg E, Nordborg C. Giant cell arteritis: epidemiological clues to its pathogenesis and an update on its treatment. Rheumatology (Oxford) 2003; 42 (03) 413-421
- 25 Liu NH, Labree LD, Feldon SE. , et al. The epidemiology of giant cell arteritis: a 12-year retrospective study. Ophthalmology 2001; 108 (06) 1145-1149
- 26 Evans JM, O'Fallon WM, Hunder GG. Increased incidence of aortic aneurysm and dissection in giant cell (temporal) arteritis. A population-based study. Ann Intern Med 1995; 122 (07) 502-507
- 27 Scheurer RA, Harrison AR, Lee MS. Treatment of vision loss in giant cell arteritis. Curr Treat Options Neurol 2012; 14 (01) 84-92
- 28 Harky A, Fok M, Balmforth D, Bashir M. Pathogenesis of large vessel vasculitis: Implications for disease classification and future therapies. Vasc Med 2019; 24 (01) 79-88
- 29 Weyand CM, Goronzy JJ. Medium- and large-vessel vasculitis. N Engl J Med 2003; 349 (02) 160-169
- 30 Nordborg E, Bengtsson BA, Nordborg C. Temporal artery morphology and morphometry in giant cell arteritis. APMIS 1991; 99 (11) 1013-1023
- 31 Weyand CM, Tetzlaff N, Björnsson J, Brack A, Younge B, Goronzy JJ. Disease patterns and tissue cytokine profiles in giant cell arteritis. Arthritis Rheum 1997; 40 (01) 19-26
- 32 Goronzy JJ, Weyand CM. Cytokines in giant-cell arteritis. Cleve Clin J Med 2002; 69 (Suppl. 02) SII91-SII94
- 33 O'Neill L, Molloy ES. The role of toll like receptors in giant cell arteritis. Rheum 2016; 55 (11) 1921-1931
- 34 Sharma BK, Jain S, Suri S, Numano F. Diagnostic criteria for Takayasu arteritis. Int J Cardiol 1996; 54 (Suppl): S141-S147
- 35 Ishikawa K, Maetani S. Long-term outcome for 120 Japanese patients with Takayasu's disease. Clinical and statistical analyses of related prognostic factors. Circulation 1994; 90 (04) 1855-1860
- 36 González-Gay MA, Blanco R, Rodríguez-Valverde V. , et al. Permanent visual loss and cerebrovascular accidents in giant cell arteritis: predictors and response to treatment. Arthritis Rheum 1998; 41 (08) 1497-1504
- 37 Danesh-Meyer H, Savino PJ, Gamble GG. Poor prognosis of visual outcome after visual loss from giant cell arteritis. Ophthalmology 2005; 112 (06) 1098-1103
- 38 de Franciscis S, Roscitano G, Serra R. , et al. Combined medical, surgical and endovascular treatment of a giant cell arteritis case manifesting as upper limbs acute ischemia. Int J Surg Case Rep 2011; 2 (05) 71-73 . Doi: 10.1016/j.ijscr.2011.02.003
- 39 Selvaraj A, Francis N, Harky A. , et al. Imaging modalities in the management of aortitis. Indian J Thorac Cardiovasc Surg 2018 . DOI: https://doi.org/10.1007/s12055-018-0710-7
- 40 Meller J, Grabbe E, Becker W, Vosshenrich R. Value of F-18 FDG hybrid camera PET and MRI in early takayasu aortitis. Eur Radiol 2003; 13 (02) 400-405
- 41 Hara M, Goodman PC, Leder RA. FDG-PET finding in early-phase Takayasu arteritis. J Comput Assist Tomogr 1999; 23 (01) 16-18
- 42 Webb M, Chambers A, AL-Nahhas A. , et al. The role of 18F-FDG PET in characterising disease activity in Takayasu arteritis. Eur J Nucl Med Mol Imaging 2004; 31 (05) 627-634
- 43 Mukhtyar C, Guillevin L, Cid MC. , et al; European Vasculitis Study Group. EULAR recommendations for the management of large vessel vasculitis. Ann Rheum Dis 2009; 68 (03) 318-323
- 44 Park JH, Chung JW, Lee KW, Park YB, Han MC. CT angiography of Takayasu arteritis: comparison with conventional angiography. J Vasc Interv Radiol 1997; 8 (03) 393-400
- 45 Numano F. Pulmonary changes in Takayasu's arteritis. Junkanki Naika 1979; 6: 97-108
- 46 Akazawa H, Ikeda U, Yamamoto K, Kuroda T, Shimada K. Hypercoagulable state in patients with Takayasu's arteritis. Thromb Haemost 1996; 75 (05) 712-716
- 47 Dasgupta B. ; Giant Cell Arteritis Guideline Development Group. Concise guidance: diagnosis and management of giant cell arteritis. Clin Med (Lond) 2010; 10 (04) 381-386
- 48 Kermani TA, Warrington KJ, Crowson CS. , et al. Large-vessel involvement in giant cell arteritis: a population-based cohort study of the incidence-trends and prognosis. Ann Rheum Dis 2013; 72 (12) 1989-1994
- 49 Weyand CM, Goronzy JJ. Clinical practice. Giant-cell arteritis and polymyalgia rheumatica. N Engl J Med 2014; 371 (01) 50-57
- 50 Hiratzka LF, Bakris GL, Beckman JA. , et al; American College of Cardiology Foundation; American Heart Association Task Force on Practice Guidelines; American Association for Thoracic Surgery; American College of Radiology; American Stroke Association; Society of Cardiovascular Anesthesiologists; Society for Cardiovascular Angiography and Interventions; Society of Interventional Radiology; Society of Thoracic Surgeons; Society for Vascular Medicine. 2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM guidelines for the diagnosis and management of patients with thoracic aortic disease: executive summary—a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines, American Association for Thoracic Surgery, American College of Radiology. Catheter Cardiovasc Interv 2010; 76 (02) E43-E86
- 51 Mackie SL, Hensor EM, Morgan AW, Pease CT. Should I send my patient with previous giant cell arteritis for imaging of the thoracic aorta? A systematic literature review and meta-analysis. Ann Rheum Dis 2014; 73 (01) 143-148
- 52 Shah PJ, Estrera AL, Miller III CC. , et al. Analysis of ascending and transverse aortic arch repair in octogenarians. Ann Thorac Surg 2008; 86 (03) 774-779
- 53 Tso E, Flamm SD, White RD, Schvartzman PR, Mascha E, Hoffman GS. Takayasu arteritis: utility and limitations of magnetic resonance imaging in diagnosis and treatment. Arthritis Rheum 2002; 46 (06) 1634-1642
- 54 Yamada I, Nakagawa T, Himeno Y, Kobayashi Y, Numano F, Shibuya H. Takayasu arteritis: diagnosis with breath-hold contrast-enhanced three-dimensional MR angiography. J Magn Reson Imaging 2000; 11 (05) 481-487
- 55 Sharma BK, Jain S, Suri S, Numano F. Diagnostic criteria for Takayasu arteritis. Int J Cardiol 1996; 54 (Suppl): S141-S147
- 56 Lin L, Tsai C, Chen M. , et al. PET in vascular diseases : applications of FDG PET/CT in vasculitis and therapeutic response. Ann Nucl Med Sci 2006; 19: 91-98
- 57 Tezuka D, Haraguchi G, Ishihara T. , et al. Role of FDG PET-CT in Takayasu arteritis: sensitive detection of recurrences. JACC Cardiovasc Imaging 2012; 5 (04) 422-429
- 58 Blockmans D, Maes A, Stroobants S. , et al. New arguments for a vasculitic nature of polymyalgia rheumatica using positron emission tomography. Rheumatology (Oxford) 1999; 38 (05) 444-447
- 59 Hautzel H, Sander O, Heinzel A, Schneider M, Müller H-W. Assessment of large-vessel involvement in giant cell arteritis with 18F-FDG PET: introducing an ROC-analysis-based cutoff ratio. J Nucl Med 2008; 49 (07) 1107-1113
- 60 Papathanasiou ND, Du Y, Menezes LJ. , et al. 18F-Fludeoxyglucose PET/CT in the evaluation of large-vessel vasculitis: diagnostic performance and correlation with clinical and laboratory parameters. Br J Radiol 2012; 85 (1014): e188-e194
- 61 Turlakow A, Yeung HW, Pui J. , et al. Fludeoxyglucose positron emission tomography in the diagnosis of giant cell arteritis. Arch Intern Med 2001; 161 (07) 1003-1007
- 62 Walter MA, Melzer RA, Graf M, Tyndall A, Müller-Brand J, Nitzsche EU. [18F]FDG-PET of giant-cell aortitis. Rheumatology (Oxford) 2005; 44 (05) 690-691 [Oxford]
- 63 Schäfer VS, Warrington KJ, Williamson EE, Kermani TA. Delayed diagnosis of biopsy-negative giant cell arteritis presenting as fever of unknown origin. J Gen Intern Med 2009; 24 (04) 532-536
- 64 Yamashita H, Kubota K, Takahashi Y. , et al. Whole-body fluorodeoxyglucose positron emission tomography/computed tomography in patients with active polymyalgia rheumatica: evidence for distinctive bursitis and large-vessel vasculitis. Mod Rheumatol 2012; 22 (05) 705-711
- 65 Prabhavalkar S, Bogusz P, Merard R, Grormley M. An Unusual Presentation of Giant Cell Arteritis. Case Rep Med 2012; 2012: 1-3
- 66 Erdogan A, Gilgil E, Oz N, Türk T, Demircan A. PTFE patching to prevent anastomotic aneurysm formation in Takayasu's arteritis. Eur J Vasc Endovasc Surg 2003; 25 (05) 478-480
- 67 Balmforth D, Harky A, Adams B, Yap J, Shipolini A, Roberts N, Uppal R, Bashir M. Is there a role for biomarkers in thoracic aortic aneurysm disease?. Gen Thorac Cardiovasc Surg 2019; 67 (01) 12-19
- 68 Min PK, Park S, Jung JH. , et al. Endovascular therapy combined with immunosuppressive treatment for occlusive arterial disease in patients with Takayasu's arteritis. J Endovasc Ther 2005; 12 (01) 28-34
- 69 Qureshi MA, Martin Z, Greenberg RK. Endovascular management of patients with Takayasu arteritis: stents versus stent grafts. Semin Vasc Surg 2011; 24 (01) 44-52
- 70 Fields CE, Bower TC, Cooper LT. , et al. Takayasu's arteritis: operative results and influence of disease activity. J Vasc Surg 2006; 43 (01) 64-71
- 71 Maksimowicz-McKinnon K, Clark TM, Hoffman GS. Limitations of therapy and a guarded prognosis in an American cohort of Takayasu arteritis patients. Arthritis Rheum 2007; 56 (03) 1000-1009
- 72 Lie JT. Aortic and extracranial large vessel giant cell arteritis: a review of 72 cases with histopathologic documentation. Semin Arthritis Rheum 1995; 24 (06) 422-431
- 73 Uchida K, Masamune A, Shimosegawa T, Okazaki K. Prevalence of IgG4-related disease in Japan based on nationwide survey in 2009. Int J Rheumatol 2012; 2012: 358371
- 74 Kasashima S, Zen Y, Kawashima A. , et al. A clinicopathologic study of immunoglobulin G4-related sclerosing disease of the thoracic aorta. J Vasc Surg 2010; 52 (06) 1587-1595
- 75 Agaimy A, Weyand M, Strecker T. Inflammatory thoracic aortic aneurysm (lymphoplasmacytic thoracic aortitis): a 13-year-experience at a German Heart Center with emphasis on possible role of IgG4. Int J Clin Exp Pathol 2013; 6 (09) 1713-1722
- 76 Pieringer H, Parzer I, Wöhrer A, Reis P, Oppl B, Zwerina J. IgG4- related disease: an orphan disease with many faces. Orphanet J Rare Dis 2014; 9: 110
- 77 Trimarchi S, Nienaber CA, Rampoldi V. , et al; IRAD Investigators. Role and results of surgery in acute type B aortic dissection: insights from the International Registry of Acute Aortic Dissection (IRAD). Circulation 2006; 114 (1, Suppl) I357-I364