Download PDF
CC BY-NC-ND 4.0 · Rev Bras Ortop (Sao Paulo) 2019; 54(03): 347-352
DOI: 10.1055/s-0039-1692450
Relato de Caso | Case Report
Sociedade Brasileira de Ortopedia e Traumatologia. Published by Thieme Revnter Publicações Ltda Rio de Janeiro, Brazil

Inoperable Sacral Giant Cell Tumor: Therapeutic Options and Pain Control[*]

Article in several languages: português | English
Eneida de Mattos Brito Oliveira Viana
1   Rede Sarah de Hospitais de Reabilitação, Brasília, DF, Brasil
,
Katia Torres Batista 
1   Rede Sarah de Hospitais de Reabilitação, Brasília, DF, Brasil
,
José Leite Carneiro Junior
1   Rede Sarah de Hospitais de Reabilitação, Brasília, DF, Brasil
› Author Affiliations
Further Information

Publication History

04 January 2018

07 May 2018

Publication Date:
27 June 2019 (online)

Also available at
   Permissions and Reprints

Abstract

Sacral giant cell tumor (GCT) is a rare condition. Its treatment is complex, since surgical removal is difficult and the response to other therapeutic options is low. The control of its growth and pain is an additional challenge. The present paper reports a case of inoperable sacral GCT, with embolization and radiotherapy for pain control as therapeutic options. The patient, a 39-year-old male, presented pain in the sacral region with lower limb irradiation due to an inoperable sacral giant cell tumor. The patient was submitted to embolization, radiotherapy, pain management with opioids and other drugs, and a rehabilitation program. Despite the difficulty in tumor growth and pain control during the follow-up, the outcome is stable after 9 years.

Keywords

giant cell tumors - orthopedics - chronic pain

* Work performed at Rede Sarah de Hospitais de Reabilitação, Brasília, DF, Brazil, and presented at the Instituto de Ensino e Pesquisa from the Hospital Sírio Libanês to obtain the certification as a specialist in the care of patients with pain.


 

  • Referências

  • 1 Camargo OP, Croci AT, Oliveira CR, Baptista AM, Caiero MT, Giannotti MA. Tumor de células gigantes: evolução histórica do seu diagnóstico e tratamento junto ao Instituto de Ortopedia e Traumatologia da FMUSP. Acta Ortop Bras 2001; 9 (04) 46-52
    CrossrefSearch in Google Scholar
  • 2 Catalan J, Fonte AC, Lusa JRB, Oliveira AD, Melo ES, Justino Júnior RO. , et al. Tumor de células gigantes ósseo: aspectos clínicos e radiográficos de 115 casos. Radiol Bras, São Paulo 2006; 39 (02) 119-122
    Search in Google Scholar
  • 3 Ciftdemir M, Kaya M, Selcuk E, Yalniz E. Tumors of the spine. World J Orthop 2016; 7 (02) 109-116
    CrossrefPubMedSearch in Google Scholar
  • 4 King T, Porreca F. Opioids in cancer pain: new considerations. Pain Clin Updates IASP. 2010; 18 (01) 1-5
    Search in Google Scholar
  • 5 Yasko AW. Interferon therapy for giant cell tumor of bone. Curr Opin Orthop 2006; 17: 568-572
    CrossrefSearch in Google Scholar
  • 6 Formenti SC, Demaria S. Systemic effects of local radiotherapy. Lancet Oncol 2009; 10 (07) 718-726
    CrossrefPubMedSearch in Google Scholar
  • 7 Branstetter DG, Nelson SD, Manivel JC, Blay JY, Chawla S, Thomas DM. , et al. Denosumab induces tumor reduction and bone formation in patients with giant-cell tumor of bone. Clin Cancer Res 2012; 18 (16) 4415-4424
    CrossrefPubMedSearch in Google Scholar
  • 8 Ferreira KAS, Kimura M, Teixeira MJ, Nobrega JC. Preditores de controle inadequado da dor entre pacientes com dor oncológica. In: 7° Congresso Brasileiro de Dor, Gramado, RS; 2006
    PubMedSearch in Google Scholar
  • 9 Junming M, Cheng Y, Dong C, Jianru X, Xinghai Y, Quan H. , et al. Giant cell tumor of the cervical spine: a series of 22 cases and outcomes. Spine 2008; 33 (03) 280-288
    CrossrefPubMedSearch in Google Scholar