Subscribe to RSS
DOI: 10.1055/s-0039-1694785
Contrast-Enhanced Ultrasound in Hepatobiliary Interventions
Publication History
19 February 2019
24 June 2019
Publication Date:
20 August 2019 (online)

Abstract
Contrast-enhanced ultrasound (CEUS) has been widely accepted as a diagnostic tool for the detection and evaluation of benign and malignant liver lesions and has been implemented into the clinical routine as a tool for percutaneous interventional real-time image guidance. CEUS can be combined with computed tomography (CT) and magnetic resonance imaging (MRI) datasets using real-time image fusion to additionally surveil proper interventional treatment and assess treatment success. This review describes the state-of-the-art use of CEUS for the surveillance and monitoring of interventional procedures of the liver and for the evaluation of postinterventional success.
-
References
- 1 Sidhu PS, Cantisani V, Dietrich CF. , et al. The EFSUMB guidelines and recommendations for the clinical practice of contrast-enhanced ultrasound (CEUS) in non-hepatic applications: update 2017 (short version). Ultraschall Med 2018; 39 (02) 154-180
- 2 Rübenthaler J, Negrão de Figueiredo G, Mueller-Peltzer K, Clevert DA. Evaluation of renal lesions using contrast-enhanced ultrasound (CEUS); a 10-year retrospective European single-centre analysis. Eur Radiol 2018; 28 (11) 4542-4549
- 3 Clevert DA, D'Anastasi M, Jung EM. Contrast-enhanced ultrasound and microcirculation: efficiency through dynamics&—current developments. Clin Hemorheol Microcirc 2013; 53 (1-2): 171-186
- 4 Greis C. Technology overview: SonoVue (Bracco, Milan). Eur Radiol 2004; 14 (Suppl. 08) 11-15
- 5 Mueller-Peltzer K, Negrao de Figueiredo G, Graf T, Rübenthaler J, Clevert DA. Papillary renal cell carcinoma in contrast-enhanced ultrasound (CEUS) - a diagnostic performance study. Clin Hemorheol Microcirc 2019; 71 (02) 159-164
- 6 Rübenthaler J, Paprottka KJ, Hameister E. , et al. Diagnostic accuracy of contrast-enhanced ultrasound (CEUS) in monitoring vascular complications in patients after liver transplantation - diagnostic performance compared with histopathological results. Clin Hemorheol Microcirc 2017; 66 (04) 311-316
- 7 Müller-Peltzer K, Rübenthaler J, Negrao de Figueiredo G, Clevert DA. CEUS-diagnosis of benign liver lesions [in German]. Radiologe 2018; 58 (06) 521-527
- 8 Rübenthaler J, Reiser M, Clevert DA. The added value of contemporary ultrasound technologies in the diagnosis of malignant tumours of the gastrointestinal system - a case report. Med Ultrason 2018; 1 (01) 105-107
- 9 Negrão de Figueiredo G, Müller-Peltzer K, Rübenthaler J, Clevert DA. CEUS-Diagnostic of malignant liver lesions [in German]. Radiologe 2018; 58 (06) 528-537
- 10 Strobel D, Bernatik T, Blank W. , et al. Diagnostic accuracy of CEUS in the differential diagnosis of small (≤20 mm) and subcentimetric (≤10 mm) focal liver lesions in comparison with histology. Results of the DEGUM multicenter trial. Ultraschall Med 2011; 32 (06) 593-597
- 11 Negrao de Figueiredo G, Rübenthaler J, Müller-Peltzer K, Clevert DA. Detection and monitoring of postinterventional success and complications of the liver using contrast-enhanced ultrasound (CEUS) - a case report after interventional treatment of a giant hemangioma. Med Ultrason 2018; 20 (04) 536-538
- 12 Schwarze V, Marschner C, Negrão de Figueiredo G. , et al. SonoVue® does not appear to cross the placenta as observed during an examination aimed at confirming a diagnosis of liver echinococcosis in a pregnant woman. Ultraschall Med 2019 (pub ahead of print). doi:10.1055/a-0837-0791
- 13 Sidhu PS, Cantisani V, Deganello A. , et al. Role of contrast-enhanced ultrasound (CEUS) in paediatric practice: an EFSUMB Position Statement. Ultraschall Med 2017; 38 (01) 33-43
- 14 Clevert DA, Jung EM. Interventional sonography of the liver and kidneys [in German]. Radiologe 2013; 53 (11) 962-973
- 15 Rübenthaler J, Wilson S, Clevert DA. Multislice computed tomography/contrast-enhanced ultrasound image fusion as a tool for evaluating unclear renal cysts. Ultrasonography 2019; 38 (02) 181-187
- 16 European Society of Radiology (ESR) Abdominal applications of ultrasound fusion imaging technique: liver, kidney, and pancreas. Insights Imaging 2019; 10 (01) 6
- 17 Jung EM, Clevert DA. Contrast-enhanced ultrasound (CEUS) and image fusion for procedures of liver interventions [in German]. Radiologe 2018; 58 (06) 538-544
- 18 Minami T, Minami Y, Chishina H. , et al. Combination guidance of contrast-enhanced US and fusion imaging in radiofrequency ablation for hepatocellular carcinoma with poor conspicuity on contrast-enhanced US/fusion imaging. Oncology 2014; 87 (Suppl. 01) 55-62
- 19 Mohr A, Jung EM, Stroszczynski C, Schacherer D, Klebl F. New economic training model for installing ultrasound-guided drainages. Z Gastroenterol 2014; 52 (11) 1257-1262
- 20 Ewertsen C, Săftoiu A, Gruionu LG, Karstrup S, Nielsen MB. Real-time image fusion involving diagnostic ultrasound. AJR Am J Roentgenol 2013; 200 (03) W249-55
- 21 Armbruster M, Rübenthaler J, Clevert DA. Diagnostic value of contrast-enhanced ultrasound in a 12-year-old girl with suspected malposition of a bladder catheter and ambiguous findings on B-mode ultrasound - a case report. Ultraschall Med 2018; 39 (05) 559-561
- 22 da Silva NPB, Beyer LP, Hottenrott MC. , et al. Efficiency of contrast enhanced ultrasound for immediate assessment of ablation status after intraoperative radiofrequency ablation of hepatic malignancies. Clin Hemorheol Microcirc 2017; 66 (04) 357-368
- 23 Meloni MF, Andreano A, Laeseke PF. , et al. Contrast-enhanced ultrasonographic findings in a brucellar hepatic abscess. J Ultrasound Med 2008; 27 (10) 1511-1515
- 24 Kishina M, Koda M, Tokunaga S. , et al. Usefulness of contrast-enhanced ultrasound with Sonazoid for evaluating liver abscess in comparison with conventional B-mode ultrasound. Hepatol Res 2015; 45 (03) 337-342
- 25 Wiesinger I, Beyer LP, Zausig N. , et al. Evaluation of integrated color-coded perfusion analysis for contrast-enhanced ultrasound (CEUS) after percutaneous interventions for malignant liver lesions: first results. Clin Hemorheol Microcirc 2018; 69 (1-2): 59-67
- 26 Pregler B, Beyer LP, Wiesinger I. , et al. Microwave ablation of large HCC lesions: added value of CEUS examinations for ablation success control. Clin Hemorheol Microcirc 2016; 64 (03) 483-490
- 27 Wiesinger I, Wiggermann P, Zausig N. , et al. Percutaneous treatment of malignant liver lesions: evaluation of success using contrast- enhanced ultrasound (CEUS) and perfusion software. Ultraschall Med 2018; 39 (04) 440-447