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CC BY-NC-ND 4.0 · Int Arch Otorhinolaryngol 2020; 24(04): e413-e422
DOI: 10.1055/s-0039-1697006
Original Research

Long-term Effects of Unilateral and Bilateral Otitis Media and Myringotomy on Long-Latency Verbal and Non-Verbal Auditory-Evoked Potentials

Milaine Dominici Sanfins 
1   Human Development Department, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, Brazil
,
Caroline Donadon
1   Human Development Department, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, Brazil
,
Letícia Reis Borges
1   Human Development Department, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, Brazil
,
Piotr H. Skarzynski
2   Department of Teleaudiology and Hearing Screening, World Hearing Center, Institute of Physiology and Pathology of Hearing, Warsaw/Kajetany, Poland
3   Department of Heart Failure and Cardiac Rehabilitation, Warsaw, Poland
4   Department of Science and Development, Institute of Sensory Organs, Warsaw, Poland
,
Maria Francisca Colella-Santos
1   Human Development Department, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, Brazil
› Author Affiliations
Funding This work was supported by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) (01-P-4346/2015) and Fundação de Apoio à Pesquisa do Estado de São Paulo (FAPESP) (889074). The funders had no role in the study design, data collection and analysis, the decision to publish, or the preparation of the manuscript.
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Abstract

Introduction Otitis media (OM) is considered one of the most common reasons patients seek medical care in childhood. The fluctuating nature of hearing loss in cases of OM leads to irregular sound stimulation of the central auditory nervous system.

Objectives To analyze the long-latency auditory-evoked potential (LLAEP) by verbal and nonverbal sounds in children with a history of OM in the first six years of life.

Methods A total of 106 schoolchildren participated in the study, 55 females and 51 males, aged between 8 and 16 years, who were divided into 3 groups: the control group (CG), the bilateral experimental group (BEG), and the unilateral experimental group (UEG). All children underwent a complete audiological evaluation (audiometry, logoaudiometry and immitance testing) and an electrophysiological evaluation (LLAEP with toneburst stimulus – LLAEP-TB, and LLAEP with speech stimulus – LLAEP-S).

Results Both study groups (BEG and UEG) presented a statistically lower performance (p < 0.005) when compared with the CG regarding all of the electrophysiological tests with the prolongation of the latency values and decrease in the amplitude values: LLAEP-TB (BEG: latency - N1, P2, N2 [females] and P300, amplitude - N1 and P2), LLAEP-S (BEG: latency - P2 and N2 [females], amplitude - P2 /UEG: latency - P2 and P300, amplitude: N1 and P2).

Conclusion Children who had suffered secretory OM in the first six years of life and who had undergone myringotomy for the placement of a ventilation tube, either unilaterally or bilaterally, presented worse performance in their electrophysiological responses to verbal and nonverbal LLAEPs.

Keywords

hearing - otitis media - electrophysiology - long-latency auditory-evoked potential - children


Publication History

Received: 14 February 2019

Accepted: 08 July 2019

Article published online:
09 January 2020

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