Unusual Synchronous Presentation of Maxillary Sinus Fibrosarcoma and Gemistocytic Astrocytoma with a Complication Called Leukocytoclastic Vasculitis: A Case Report

Bilge Cadir; Nermin Karahan; Serdar Nasir; M. Asim Aydin; S.Suha Turkaslan

doi:10.1055/s-0039-1697438

European Journal of Dentistry, Table of Contents

CC BY-NC-ND 4.0 · Eur J Dent 2009; 03(03): 233-239
DOI: 10.1055/s-0039-1697438

Original Article

Unusual Synchronous Presentation of Maxillary Sinus Fibrosarcoma and Gemistocytic Astrocytoma with a Complication Called Leukocytoclastic Vasculitis: A Case Report

Bilge Cadir

¹Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Suleyman Demirel University, Isparta, Turkey.

,

Nermin Karahan

²Department of Pathology, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey.

,

Serdar Nasir

³Department of Plastic and Reconstructive Surgery, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey.

,

M. Asim Aydin

³Department of Plastic and Reconstructive Surgery, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey.

,

S.Suha Turkaslan

⁴Department of Prosthetics, Faculty of Dentistry, Suleyman Demirel University, Isparta, Turkey.

› Author Affiliations

Abstract

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ABSTRACT

Fibrosarcoma of the paranasal sinuses is extremely rare pathology and there is limited report in the literature. We report synchronous presentation of maxillary sinus fibrosarcoma and gemistocytic astrocytoma which is, to our knowledge, unique in the literature. Both tumors metastases to other organ rarely and the metastatic spread of gemistocytic astrocytoma to fibrosarcoma or vice versa have also not been reported in the literature yet. This report discusses the clinical course of the disease, outcome of the treatment approach and survival as well as an unusual occurrence of leukocytoclastic vasculitis during the course of radiotherapy in such unusual presentation. (Eur J Dent 2009;3:233-239)

Key words:

Fibrosarcoma - Gemistocytic astrocytoma - Synchronous cancer - Maxillary sinus - Leukocytoclastic vasculitis - Radiotherapy

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References

REFERENCES
1 Osguthorpe JD, Richardson M. Frontal sinus malignancies. Otolaryngol Clin North Am 2001;34:269-281.
2 Wanebo HJ, Kones RJ, MacFarlane JK, Eilber FR, Byers RM, Elias EG, et al. Head and neck sarcoma: report of the Head and Neck Sarcoma Registry Society of Head and Neck Surgeons Committee on Research. Head Neck 1992;14:1-7.
3 Figueiredo MT, Marques LA, Campos-Filho N. Soft-tissue sarcomas of the head and neck in adults and children: experience at a single institution with a review of literature. Review. Int J Cancer 1988;15:198-200.
4 Gorsky M, Epstein JB. Head and neck and intra-oral soft tissue sarcomas. Oral Oncol 1998;34:292-296.
5 Krouwer HG, Davis RL, Silver P, Prados M. Gemistocytic astrocytomas: a reappraisal. J Neurosurg 1991;74:399-406.
6 Kleihues P, Davis RL, Ohgaki H, Burger PC, Westphal MM, Cvenee WK. Diffuse astrocytoma. In: Kleihues P, Cavenee WK, editors. Pathology and genetics of tumors of the nervous system. Lyon: IARC Press 2000;22-26.
7 Okamoto Y, Di Patre PL, Burkhard C, Horstmann S, Jourde B, Fahey M, et al. Population-based study on incidence, survival rates, and genetic alterations of low-grade diffuse astrocytomas and oligodendrogliomas. Acta Neuropathol 2004;108:49-56.
8 Sanroman JF, Hoyo JRA, Diaz FJ, Gil-Diez L, Monje F, Naval L, Alamillos FJ, Rubio ADP. Sarcomas of the head and neck. Br J Oral Maxillofac Surg 1992;30:115�118.
9 Nagler RM, Malkin L, Ben-Arieh Y, Laufer D. Sarcoma of the maxillofacial region, follow-up of 25 cases. Anticancer Res 2000;20:3735�3742.
10 Pandey M, Thomas G, Mathew A, Abraham EK, Somanathan T, Ramadas K, type EM, Ahamed IM, Sebastain P, Nair MK. Sarcoma of the oral and maxillofacial soft tissue in adults. Eur J Surg Oncol 2000;26:145�148.
11 Yamaguchi S, Nagasawa H, Suzuki T, Fujii E, Iwaki H, Takagi M, et al. Sarcomas of the oral and maxillofacial region: a review of 32 cases in 25 years. Clin Oral Investig 2004;8:52-55.
12 Katzenmeyer K, Pou A. Neoplasms of the Nose and Paranasal Sinus. In: Dr.Quinn�s Online Textbook of Otolaryngology. June 7, 2000.
13 Le QT, Fu KK, Kaplan M, Terris DJ, Fee WE, Goffinet DR. Treatment of maxillary sinus carcinoma: a comparison of the 1997 and 1977 American Joint Committee on cancer staging systems. Cancer 1999;86:1700-1711.
14 Ou SM. Soft tissue sarcoma in the head and neck�analysis of 87 patients. Zhonghua Zhong Li Za Zhi 1988;10:289-292.
15 Hayashi T, Nonaka S, Bandoh N, Kobayashi Y, Imada M, Harabuchi Y. Treatment outcome of maxillary sinus squamous cell carcinoma. Cancer 2001;92:1495-1503.
16 Eeles RA, Fisher C, A� Hern RP, Robinson M, Rhys-Evans P, Henk JM, Archer D, Harmer CL. Head and neck sarcomas, prognostic factors and implications for treatment. Br J Cancer 1993;68:201�207.
17 Greer JM, Longley S, Edwards NL, Elfenbein GJ, Panush RS. Vasculitis associated with malignancy. Experience with 13 patients and literature review. Review. Medicine (Baltimore) 1988; 67: 220-230.
18 Hutson TE, Hoffman GS. Temporal concurrence of vasculitis and cancer: a report of 12 cases. Arthritis Care Res 2000;13:417-423.