Profile of Laryngeal Microsurgeries in Patients Over 60 Years Old

Abstract

Introduction The increase in life expectancy is an incentive to the development of researches with the elderly population aiming at actions that may ensure healthy and active aging.

Objective To analyze the profile of laryngeal microsurgery performed in patients > 60 years old.

Methods A retrospective observational study, with a cross-sectional design. A retrospective analysis of the medical records of elderly patients submitted to laryngeal microsurgery was performed at a private hospital in Curitiba, state of Paraná, Brazil, between January 2004 and December 2016. Were included all of the patients > 60 years old that underwent laryngeal microsurgery during this period.

Results During the studied period, 213 laryngeal microsurgeries were performed in 181 patients > 60 years old. There was a preponderance of male patients. The mean age was 67.6 years old. Squamous cell carcinoma (SCC) was the most prevalent disorder (26%), followed by Reinke edema (20%), papillomatosis (14%), polyps (11%), leukoplakia (8%), minor structural alterations (8%), associated lesions (9%), and others (4%). Men presented a higher probability of SCC diagnosis, regardless of the age group, while Reinke edema was more frequently observed in women. A directly proportional relation between the frequency of laryngeal cancer and age increase was also observed. No significant differences were observed in professional voice users.

Conclusion Further researches are required to properly comprehend the factors associated with laryngeal lesions and determine prevention and treatment approaches.

Keywords

Microsurgery - larynx - elderly - squamous cell carcinoma - reinke edema

• References

• 1 UNFPA and HelpAge International. Ageing in the Twenty-First Century: A Celebration and A Challenge. New York: United Nations Population Fund; 2012
• 2 Matos DL, Giatti L, Lima-Costa MF. Fatores sócio-demográficos associados ao uso de serviços odontológicos entre idosos brasileiros: um estudo baseado na Pesquisa Nacional por Amostra de Domicílios. Cad Saude Publica 2004; 20 (05) 1290-1297
• 3 Roy N, Kim J, Courey M, Cohen SM. Voice disorders in the elderly: A national database study. Laryngoscope 2016; 126 (02) 421-428
• 4 Zhukhovitskaya A, Battaglia D, Khosla SM, Murry T, Sulica L. Gender and age in benign vocal fold lesions. Laryngoscope 2015; 125 (01) 191-196
• 5 Slavit DH. Phonosurgery in the elderly: a review. Ear Nose Throat J 1999; 78 (07) 505-509 , 512
• 6 Roy N, Merrill RM, Gray SD, Smith EM. Voice disorders in the general population: prevalence, risk factors, and occupational impact. Laryngoscope 2005; 115 (11) 1988-1995
• 7 Woo SH, Kim RB, Choi SH, Lee SW, Won SJ. Prevalence of laryngeal disease in South Korea: data from the Korea National Health and Nutrition Examination Survey from 2008 to 2011. Yonsei Med J 2014; 55 (02) 499-507
• 8 Melo ECM, Brito LL, Brasil OCO, Behlau M, Melo DM. Incidência de lesões laríngeas não neoplásicas em pacientes com queixas vocais. Rev Bras Otorrinolaringol 2001; 67 (06) 788-794
• 9 Döbrossy L. Epidemiology of head and neck cancer: magnitude of the problem. Cancer Metastasis Rev 2005; 24 (01) 9-17
• 10 Brouha XD, Tromp DM, de Leeuw JR, Hordijk GJ, Winnubst JA. Laryngeal cancer patients: analysis of patient delay at different tumor stages. Head Neck 2005; 27 (04) 289-295
• 11 Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin 2005; 55 (02) 74-108
• 12 Moreno AB, Lopes CS. Avaliação da qualidade de vida em pacientes laringectomizados: uma revisão sistemática. Cad Saude Publica 2002; 18 (01) 81-92
• 13 Hortense FTP, Carmagnani MIS, Brêtas ACP. O significado do tabagismo no câncer de laringe. Rev Bras Enferm Brasília 2008; 61 (01) 24-30
• 14 Ruiz MT, Pavarino-Bertelli É, Maniglia JV, Ruback MJC, Goloni-Bertollo EM. Epidemiologia e biomarcadores em câncer de cabeça e pescoço. Arq Ciênc Saúde 2006; 13 (01) 34-38
• 15 Bradley PJ, Raghavan U. Cancers presenting in the head and neck during pregnancy. Curr Opin Otolaryngol Head Neck Surg 2004; 12 (02) 76-81
• 16 Martins RHG, Domingues MA, Fabro AT, Dias NH, Santana MF. Edema de Reinke: estudo da imunoexpressão da fibronectina, da laminina e do colágeno IV em 60 casos por meio de técnicas imunoistoquímicas. Rev Bras Otorrinolaringol (Engl Ed) 2009; 75 (06) 821-825
• 17 García Alvarez CD, Campos Bañales ME, López Campos D, Rivero J, Pérez Piñero B, López Aguado D. [Polyps, nodules, and Reinke edema. . An epidemiological and histopathological study]. Acta Otorrinolaringol Esp 1999; 50 (06) 443-447
• 18 Franco RA, Andrus JG. Common diagnoses and treatments in professional voice users. Otolaryngol Clin North Am 2007; 40 (05) 1025-1061 , vii
• 19 Catani GSA. Estudo da percepção vocal e análise acústica pré e pós-operatória em pacientes profissionais da voz submetidos à microcirurgia de laringe. Curitiba, Tese: Universidade Federal do Paraná; 2015
• 20 Aaltonen LM, Rihkanen H, Vaheri A. Human papillomavirus in larynx. Laryngoscope 2002; 112 (04) 700-707
• 21 Silva AMTC, Cruz AD, Silva CC, Borges FR, Curado MP. Genotipagem de Papiloma Vírus Humano em paciente com papilomatose laríngea recorrente. Rev Bras Cancerol 2003; 49 (03) 167-174