Indian Journal of Plastic Surgery, Inhaltsverzeichnis CC BY-NC-ND 4.0 · Indian J Plast Surg 2006; 39(02): 182-184DOI: 10.1055/s-0039-1699155 Case Report Association of Plastic Surgeons of India Mucormycosis at pectoralis major myocutaneous flap donor site A Saraiya Hemant Sushrut Plastic Surgery Research Center, Ahmedabad, , A Tankshali Rajen Gujarat Cancer and Research Institute, Apollo Hospital, › Institutsangaben Artikel empfehlen Abstract als PDF herunterladen ABSTRACT Background: Advanced carcinomas involving the head and neck present a major therapeutic challenge because of their poor prognosis particularly in old age irrespective of the treatment modality used. Materials and Methods: A 71-year-old patient presented with right-sided buccal mucosal carcinoma involving the mandible. Composite resection with removal of mandible and radical neck dissection was done. Pectoralis major myocutaneous flap (PMMC) with deltopectoral flap was done to cover the defect. On the 14th day mucormycosis was noted on pectoralis major myocutaneous flap donor site. Radical debridement and appropriate antibiotic and antifungal treatment was started. The patient was put on life support system. Results:Despite aggressive treatment the patient died. Conclusion:This case reaffirms the views that radical surgical procedure should be carried out with caution in old patients with preexisting diseases as the chances of life-threatening complications are very high in these patients. Mucormycosis at pectoralis major myocutaneous flap (PMMC) donor site is probably being reported for the first time KEY WORDS KEY WORDSBuccal cell carcinoma - mucormycosis - pectoralis major myocutaneous flap PDF (582 kb) Referenzen 1 Greenberg RN, Scott LJ, Vaughn HH, Ribes JA. Zygomycosis (mucormycosis): Emerging clinical importance and new treatments. Curr Opin Infect Dis 2004; 17: 517-25 2 Lin CS, Jen YM, Cheng MF, Lin YS, Su WF, Hwang JM. et al. Squamous cell carcinoma of the buccal mucosa: An aggressive cancer requiring multimodality treatment. Head Neck 2006; 28: 150-7 3 Sonis ST, Fey EG. Oral complications of cancer therapy. Oncology (Williston Park) 2002; 16: 680-68 4 Vissink A, Jansma J, Spijkervet FK, Burlage FR, Coppes RP. Oral sequelae of head and neck radiotherapy. Crit Rev Oral Biol Med 2003; 14: 199-212 5 Taylor 4th SG, Murthy AK, Vannetzel JM, Colin P, Dray M, Caldarelli DD. et al. Randomized comparision of neoadjuvant cisplatin and fluorouracil infusion followed by radiation versus concomitant treatment in advanced head and neck cancer. J Clin Oncol 1994; 12: 385-95 6 Nagy B, Molnar J, Rovo L, Paczona R, Thurzo L. Radiotherapy in combination with low-dose chemotherapy in locally advanced head and neck cancer Magy Onkol. 2004; 48: 145-9 7 Shah J, Patel SG. Principles of radiation oncology in Head and neck surgery and oncology. 3rd ed. Mosby; New York: 2003: p. 643-62 8 Blair EA, Callender DL. Head and neck cancer: The problem. Clinics in plastic surgery - Head and neck reconstruction. WB Saunders; Philadelphia: 1994: p. 1-7
